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exercise-induced bronchoconstriction Diagnostics:Impact of a Repeated exercise Challenge Test

Open Journal of Respiratory Diseases 2014年第2期4卷 55-63页

作者： Maj R.Angell Liv Berit Augestad Thorbjorn S.Haugen Anne Frostad Thor Arne Gronnerod Trine Stensrud Department of Human Movement Science Faculty of Social Sciences and Technology ManagementNorwegian University of Science and Technology(NTNU)TrondheimNorway Clinic for Allergy and Airway Diseases OsloNorway Department of Sports Medicine Norwegian School of Sport SciencesOsloNorway

exercise-induced bronchoconstriction (EIB) is related to increased ventilation (VE) during exercise and describes the transient airway narrowing following exercise. A reliable diagnosis is essential for optimal treatment. The impact of a repeated exercise challenge test (ECT) in a clinical setting is not well established and conducting a repeated ECT with the possibility to adjust the exercise intensity on an individual basis may give more information. The aim of the study was to evaluate the test-retest reliability of an ECT for EIB and its association with exercise intensity. Methods: After examination by a pulmonologist, 20 referred subjects with symptoms strong indications of exercise-induced bronchoconstriction performed two consecutive exercise challenge tests on a treadmill. The exercise intensity of the repeated test was adjusted. Forced expiratory volume in 1 second (FEV1) was measured before and 1, 3, 6, 10, and 15 minutes after exercise. EIB was defined as a reduction of ≥ 10% in FEV1. Ventilation and heart rate were measured during exercise. Results: Five subjects tested positive in both tests, and ten subjects tested negative in both tests. Three subjects tested positive in the first test only, while two subjects tested positive in the second test only. The exercise intensity was not significantly different between the two tests for any of the subjects. Conclusion: There were 25% divergences in the diagnostic results of two consecutive exercise challenge tests. The difference in the test results was not explained by a difference in the exercise intensity.

关键词： exercise-induced bronchoconstriction exercise Challenge Test Forced Expiratory Volume in 1 Second exercise Intensity

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