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cancer: An unknown territory;rethinking before going ahead

Genes & Diseases 2021年第5期8卷 655-661页

作者： Arun Upadhyay Department of Biochemistry Central University of RajasthanRajasthan305817India

cancer is a disease of altered signaling and metabolism,causing uncontrolled divi-sion and survival of transformed cells.A host of molecules,factors,and conditions have been designated as underlying causes for the inception and progression of the *** enormous amount of data is available,system-wide interaction networks of the genes and proteins are generated over the years and have now reached up to a level of saturation,where we need to shift our focus to the more advanced and comprehensive methods and approaches of data analysis and *** with the availability of enormous literature on this one of the most pressing pathological conditions,a successful cure of the disease seems to be *** treatment plans,like immunotherapy and precision medicine,are being employed for different ***,their actual benefits to the patients would be known only after the evaluation of clinical data over the next few ***,we need to look at few fundamental challenges that should be addressed in more depth before we could devise bet-ter,rigorous,and comprehensive treatment plans and may successfully reach a possible cure of the *** article aims at bringing attention towards some fundamental gaps in our approach towards the disease that leads to failure in devising successful therapeutics.

关键词： Bottom-up approach evolution of cancer Genetic diversity Immunotherapy Multimodal treatment

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