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检索条件"主题词=Epigenetic interplay"
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Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
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Acta Pharmaceutica Sinica B 2023年 第6期13卷 2601-2612页
作者: Xiaomin Wang Jun Xu Yiming Sun Siyuwei Cao Hanlin Zeng Nan Jin Matthew Shou Shuai Tang Yi Chen Min Huang Cancer Research Center State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China University of Chinese Academy of Sciences Beijing 100049China School of Pharmaceutical Science and Technology Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China Division of Diabetes Endocrinology and MetabolismDepartment of Molecular Physiology and BiophysicsVanderbilt University Medical CenterNashvilleTN 37232USA
epigenetic therapies that cause genome-wide epigenetic alterations,could trigger local interplay between different histone marks,leading to a switch of transcriptional outcome and therapeutic responses of epigenetic *... 详细信息
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