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Safety and effectiveness of butorphanol in epidural labor analgesia:A protocol for a systematic review and meta-analysis

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World Journal of Clinical Cases 2024年第8期12卷 1416-1421页

作者： Guan-Cheng Tang Man He Zhen-Zhao Huang Yan Cheng Department of Anesthesiology Yongkang Hospital of Traditional Chinese MedicineJinhua 321301Zhejiang ProvinceChina Department of Gynecology and Obstetrics Yongkang Hospital of Traditional Chinese MedicineJinhua 321301Zhejiang ProvinceChina Department of Anesthesiology Hangzhou United Liger Sixth Medical Beauty HospitalHangzhou 311215Zhejiang ProvinceChina Department of Ultrasound Hangzhou Women’s HospitalHangzhou 310008Zhejiang ProvinceChina

BACKGROUND epidural analgesia is the most effective analgesic method during *** administered epidurally has been shown to be a successful analgesic method during ***,no comprehensive study has examined the safety and efficacy of using butorphanol as an epidural analgesic during *** To assess butorphanol's safety and efficacy for epidural labor *** The PubMed,Cochrane Library,EMBASE,Web of Science,China National Knowledge Infrastructure,and Google Scholar databases will be searched from *** types of literature,such as conference abstracts and references to pertinent reviews,will also be *** will include randomized controlled trials comparing butorphanol with other opioids combined with local anesthetics for epidural analgesia during *** will be no language *** primary outcomes will include the visual analog scale score for the first stage of labor,fetal effects,and Apgar *** independent reviewers will evaluate the full texts,extract data,and assess the risk of *** bias will be evaluated using Egger's or Begg's tests as well as visual analysis of a funnel plot,and heterogeneity will be evaluated using the Cochran Q test,P values,and I2 ***-analysis,subgroup analysis,and sensitivity analysis will be performed using RevMan software version *** protocol was developed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)Protocols statement,and the PRISMA statement will be used for the systematic *** This study provides reliable information regarding the safety and efficacy of using butorphanol as an epidural analgesic during *** To support clinical practice and development,this study provides evidence-based findings regarding the safety and efficacy of using butorphanol as an epidural analgesic during labor.

关键词： epidural analgesia during labor Butorphanol Safety Protocol Meta-analysis

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