检索结果-南通市图书馆

epidemiological investigation of clonorchiasis in Guangdong Shunde from 2014 to 2015

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Epidemiological investigation of clonorchiasis in Guangdong ...

Application of big data and artificial intelligence in epidemic surveillance and containment

中国动物学会寄生虫学专业委员会第十届全国寄生虫学青年工...

作者： Yihai Yu Yanluan Li Shuang Zhao Kun Wu Key Laboratory of Prevention and Control for Emerging Infectious Diseases of Guangdong Higher I nstitutes Department of Pathogen Biology School of Public Health Southern Medical University

Objective: This project has investigated the popular trends and characteristics, population infection, the correlated knowledge of the public towards liver fluke infection, the changing to eating habits, the diagnosis and treatments of local medical institutions for the disease, infection of the intermediate host in Shunde of Guangdong province. Provide some meaningful insights and suggestions for the prevention and treatment of the disease. Method: The data of the eggs in feces of Shunde residents over the years were analyzed to understand the situation and development trend of the liver fluke infection. The data of the questionnaire survey were analyzed which was related knowledge for the disease, living habits, medical treatment and so on in Shunde to understand their knowledge level about liver fluke and behaviors. Analyzing the previous sampling survey data in Shunde, and understanding the situation of freshwater fish infected liver fluke metacercariae. Detection methods of local medical institutions were investigated to understand the influence factors on detection rate. Result: In this survey, 1536 residents accepted the fecal examination, of which 651 people are infected, and the infection rate is 42.38%;Standardized infection rate is 39.98%. Among the infected people, there were more male than female, and the difference is significant(λ2=54.793,p<0.001). And there are significant differences among different age groups(λ2 =272.500, p<0.001) and the infection rate increases with age. 52.64% of men and 33.78% of women had ever been eating raw freshwater fish and shrimp. Both have significant difference(p < 0.001). There is a declining trend on the infection rate and infectiosity of freshwater fish that farmed or sold in Shunde comparing with previous the literatures survey in recent years. The physiological saline direct smear method and the modified Kato s thick smear method detected liver fluke infection with significant difference(P < 0.01) and increasing the number of fecal samples can significantly imp

关键词： Clonorchis sinensis Modified Kato’s method Questionnaire survey Freshwater fish epidemiological investigation

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Intelligent Medicine 2023年第1期3卷 36-43页

作者： Zengtao Jiao Hanran Ji Jun Yan Xiaopeng Qi AI lab Yidu Cloud(Beijing)Technology Co.Ltd.Beijing 100083China Center for Global Public Health Chinese Center for Disease Control and PreventionBeijing 102206China

Faced with the current time-sensitive COVID-19 pandemic,the overburdened healthcare systems have resulted in a strong demand to develop newer methods to control the spread of the pandemic.Big data and artificial intelligence(AI)have been leveraged amid the COVID-19 pandemic;however,little is known about their use for supporting public health efforts.In epidemic surveillance and containment,efforts are needed to treat critical patients,track and manage the health status of residents,isolate suspected cases,and develop vaccines and antiviral drugs.The applications of emerging practices of artificial intelligence and big data have become powerful"weapons"to fight against the pandemic and provide strong support in pandemic prevention and control,such as early warning,analysis and judgment,interruption and intervention of epidemic,to achieve goals of early detection,early report,early diagnosis,early isolation and early treatment.These are the decisive factors to control the spread of the epidemic and reduce the mortality.This paper systematically summarized the application of big data and AI in epidemic,and describes practical cases and challenges with emphasis on epidemic prevention and control.The included studies showed that big data and AI have the potential strength to fight against COVID-19.However,many of the proposed methods are not yet widely accepted.Thus,the most rewarding research would be on methods that promise value beyond COVID-19.More efforts are needed for developing standardized reporting protocols or guidelines for practice.

关键词： Epidemic prevention and control epidemiological investigation Artificial intelligence Big data Early

An agent-based model with antibody dynamics information in COVID-19 epidemic simulation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Infectious Disease Modelling 2023年第4期8卷 1151-1168页

作者： Zhaobin Xu Jian Song Weidong Liu Dongqing Wei Department of Life Science Dezhou UniversityShandong253023China Department of Physical Education Dezhou UniversityShandong253023China School of Life Sciences and Biotechnology Shanghai Jiao Tong UniversityShanghai200030China

Accurate prediction of the temporal and spatial characteristics of COVID-19 infection is of paramount importance for effective epidemic prevention and control.In order to accomplish this objective,we incorporated individual antibody dynamics into an agent-based model and devised a methodology that encompasses the dynamic behaviors of each individual,thereby explicitly capturing the count and spatial distribution of infected individuals with varying symptoms at distinct time points.Our model also permits the evaluation of diverse prevention and control measures.Based on our findings,the widespread employment of nucleic acid testing and the implementation of quarantine measures for positive cases and their close contacts in China have yielded remarkable outcomes in curtailing a less transmissible yet more virulent strain;however,they may prove inadequate against highly transmissible and less virulent variants.Additionally,our model excels in its ability to trace back to the initial infected case(patient zero)through early epidemic patterns.Ultimately,our model extends the frontiers of traditional epidemiological simulation methodologies and offers an alternative approach to epidemic modeling.

关键词： COVID-19 Agent-based method Antibody dynamics Epidemic prediction Targeted epidemic-control measures epidemiological investigation

Accelerated Evolution of H7N9 Subtype Influenza Virus under Vaccination Pressure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Virologica Sinica 2021年第5期36卷 1124-1132页

作者： Yifan Wu Jingkai Hu Xuanjiang Jin Xiao Li Jinfeng Wang Mengmeng Zhang Jianglin Chen Shumin Xie Wenbao Qi Ming Liao Weixin Jia National Avian Influenza Para-Reference Laboratory(Guangzhou) College of Veterinary MedicineSouth China Agricultural UniversityGuangzhou 510642China Key Laboratory of Zoonosis Key Laboratory of Animal Vaccine DevelopmentMinistry of Agriculture and Rural AffairsGuangzhou 510642China Guangdong Laboratory for Lingnan Modern Agriculture Guangzhou 510642China National and Regional Joint Engineering Laboratory for Medicament of Zoonosis Prevention and Control Guangzhou 510642China Key Laboratory of Zoonoses Prevention and Control of Guangdong Province Guangzhou 510642China

No avian H7 N9 outbreaks have occurred since the introduction of H7 N9 inactivated vaccine in the fall of 2017.However,H7 N9 is still prevalent in poultry.To surveil the prevalence,genetic characteristics,and antigenic changes of H7 N9,over7000 oropharyngeal and cloaca swab specimens were collected from live poultry markets and farms in 15 provinces of China from 2017 to 2019.A total of 85 influenza virus subtype H7 N9 strains were isolated and 20 representative strains were selected for genetic analysis and antigenicity evaluation.Results indicated the decreased prevalence of low-pathogenic H7 N9 strains while highly-pathogenic H7 N9 strains became dominated since the introduction of vaccine.Phylogenetic analysis showed that strains from 2019 formed an independent small branch and were genetically distant to strains isolated in 2013–2018.Analysis of key amino acid sites showed that the virus strains may adapt to the host environment evolutionally through mutation.Our analysis predicted additional potential glycosylation sites for HA and NA genes in the 2019 strains.Sequence analysis of HA gene in strains isolated from 2018 to 2019 showed that there were an increased nucleotide substitution rate and an increased mutation rate in the first and second nucleotides of coding codons within the open reading frame.The hemagglutination inhibition(HI)assay showed that H7-Re1 and H7-Re2 exhibited a lower HI titer for isolates from 2019,while H7-Re3 and r LN79 showed a high HI titer.The protective effect of the vaccine decreased after15 months of use.Overall,under vaccination pressure,the evolution of influenza virus subtype H7 N9 has accelerated.

关键词： H7N9 Genetic evolution epidemiological investigation Hemagglutination inhibition assay Vaccination pressure

A large outbreak of acute gastroenteritis caused by the human norovirus GII.17 strain at a university in Henan Province,China

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Infectious Diseases of Poverty 2017年第1期6卷 42-50页

作者： Xue-Yong Huang Jia Su Qian-Chao Lu Shi-Zheng Li Jia-Yong Zhao Meng-Lei Li Yi Li Xiao-Jing Shen Bai-Fan Zhang Hai-Feng Wang Yu-Jiao Mu Shu-Yu Wu Yan-Hua Du Li-Cheng Liu Wei-Jun Chen John David Klena Bian-Li Xu Henan Center for Disease Control and Prevention ZhengzhouChina Henan Key Laboratory of Pathogenic Microorganisms ZhengzhouChina Nanyang City Center for Disease Control and Prevention NanyangChina Program of Global Disease Detection US Centers for Disease Control and PreventionBeijingChina State Key Laboratory of Pathogens and Biosecurity Institute of Microbiology and EpidemiologyAcademy of Military Medical SciencesBeijingChina Key Laboratory of Genome Sciences and Information Beijing Institute of GenomicsChinese Academy of SciencesBeijingChina Division of Global Health Protection Center for Global HealthCenters for Disease Control and PreventionAtlantaUSA

Background:Human noroviruses are a major cause of viral gastroenteritis and are the main etiological agents of acute gastroenteritis outbreaks.An increasing number of outbreaks and sporadic cases of norovirus have been reported in China in recent years.There was a large acute gastroenteritis outbreak at a university in Henan Province,China in the past five years.We want to identify the source,transmission routes of the outbreak by epidemiological investigation and laboratory testing in order to provide the effective control measures.Methods:The clinical cases were investigated,and analysed by descriptive epidemiological methods according to factors such as time,department,grade and so on.Samples were collected from clinical cases,healthy persons,the environment,water,and food at the university.These samples were tested for potential bacteria and viruses.The samples that tested positive for norovirus were selected for whole genome sequencing and the sequences were then analysed.Results:From 4 March to 3 April 2015,a total of 753 acute diarrhoea cases were reported at the university;the attack rate was 3.29%.The epidemic curve showed two peaks,with the main peak occurring between 10 and 20 March,accounting for 85.26%of reported cases.The rates of norovirus detection in samples from confirmed cases,people without symptoms,and environmental samples were 32.72%,17.39%,and 9.17%,respectively.The phylogenetic analysis showed that the norovirus belonged to the genotype GII.17.Conclusions:This is the largest and most severe outbreak caused by genotype GII.17 norovirus in recent years in China.The GII.17 viruses displayed high epidemic activity and have become a dominant strain in China since the winter of 2014,having replaced the previously dominant GII.4 Sydney 2012 strain.

关键词： Human norovirus Acute gastroenteritis outbreak epidemiological investigation Phylogenetic analysis Henan Province China

Risk of group aggregative behavior during COVID-19 outbreak: A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2021年第1期9卷 170-174页

作者： Hui Zuo Zhi-Bing Hu Feng Zhu Infection Control and Administration Guangzhou Twelfth People’s HospitalGuangzhou 510620Guangdong ProvinceChina Molecular Epidemiology Research Group Guangzhou Twelfth People’s HospitalGuangzhou 510620Guangdong ProvinceChina Central Laboratory Guangzhou Occupation Disease Preventive and Treatment CentreGuangzhou 510620Guangdong ProvinceChina

BACKGROUND At the end of 2019,a new epidemic of viral pneumonia emerged in China and was determined to be caused by a novel coronavirus,which was named coronavirus disease 2019(COVID-19)by the World Health Organization.The epidemic quickly spread,causing a worldwide pandemic.Scientists and clinicians across the globe have shifted their research efforts towards understanding the virus itself and its epidemiology.CASE SUMMARY In mid-January 2020,a Chinese family made a visit to a local city,and within the next 2 wk one after another fell ill with COVID-19.At the beginning of their first illness onset,the family had eaten in a restaurant,which led to the subsequent illness onset in another two families.All cases were diagnosed as COVID-19 by real-time fluorescent reverse transcription-polymerase chain reaction.epidemiological investigation showed that the transmission chain was complete.CONCLUSION This chain of social exposure highlights the danger of group aggregative behavior for spread of COVID-19.

关键词： COVID-19 epidemiological investigation Group aggregative behavior Novel coronavirus Pandemic Social exposure Case report

Prevalence of severe fever with thrombocytopenia syndrome virus in animals in Henan Province, China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Infectious Diseases of Poverty 2019年第3期8卷 82-87页

作者： Xue-Yong Huang Yan-Hua Du Hai-Feng Wang Ai-Guo You Yi Li Jia Su Yi-Fei Nie Hong-Xia Ma Bian-Li Xu Henan Center for Disease Control and Prevention ZhengzhouChina Henan Key Laboratory of Pathogenic Microorganisms ZhengzhouChina

Severe fever with thrombocytopenia syndrome(SFTS)is an emerging infectious disease caused by severe fever with thrombocytopenia syndrome virus(SFTSV).SFTSV has been found in humans,ticks and animals,and SFTS has high mortality and increasing prevalence in East Asia.In the study,the samples(heart,liver,lung,kidney,spleen,brain tissue and serum)were collected from 374 domestic animals and 241 wild animals in Pingqiao District and Xinxian County of Xinyang in Henan Province,China.275(44.72%,275/615)animals were positive for anti-SFTSV antibodies,the anti-SFTSV antibodies positive ratios of domestic and wild animals were 43.58%(163/374)and 46.47%(112/241),respectively.There was no significant difference in domestic and wild animals,but significant differences were detected among different species of animals(x^2=112.59,P<0.0001).Among 615 animals,105(17.07%,105/615)animals were positive for SFTSV RNA,and only one SFTSV strain was isolated from heart tissue of a yellow weasel.The phylogenetic analysis shows that the sequence from animals belonged to the same group with viral sequences obtained from humans.The animals maybe play a reservoir host in maintaining the life cycle of SFTSV in nature.

关键词： Severe fever with thrombocytopenia syndrome virus epidemiological investigation Animal Reservoir host

Diagnosis and treatment of an elderly patient with 2019-nCoV pneumonia and acute exacerbation of chronic obstructive pulmonary disease in Gansu Province:A case report

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2020年第17期8卷 3903-3910页

作者： Tian-Peng He Dong-Liang Wang Jing Zhao Xiao-Ying Jiang Jin He Jian-Ke Feng Yuan Yuan First Department of Critical Care Medicine Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina Department of Medical Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina Department of Medical Infectious Diseases of Gansu Provincial HospitalTianshui 741024Gansu ProvinceChina

BACKGROUND In December 2019,the first patient with 2019-novel coronavirus(2019-nCoV)was reported in Wuhan,China,and the disease spread rapidly across the country and surrounding countries within 2 mo.As of February 29,2020,a total of 91 confirmed cases had been reported in Gansu Province.This case report of the diagnosis and treatment of an elderly patient with 2019-nCoV pneumonia complicated by acute exacerbation of chronic obstructive pulmonary disease in Gansu Province aims to provide a better reference for the treatment of patients in the future.CASE SUMMARY The patient,a 94-year-old female,lived in Maiji District of Tianshui,Gansu Province,China.On January 30,2020,she was admitted to the Fourth People’s Hospital of Tianshui after 9 d of close contact with a patient with 2019-nCoV pneumonia.She was subsequently admitted to Gansu Provincial Hospital of Traditional Chinese Medicine for isolation and transferred to Tianshui Gansu Provincial Hospital of Infectious Diseases on February 3,2020 for treatment.Upon initial examination,her body temperature was 36.7°C,pulse was 80,breathing was 20,and blood pressure was 130/80 mmHg.She was conscious with normal development and normal nutrition.The pharynx was not red,and bilateral tonsils were not red and swollen.The lungs sounded slightly coarse with no dry or wet rales.The first symptoms were cough and fatigue on 2 February.The patient was hospitalized for 12 d.After active treatment,she was discharged on February 14 with a good prognosis.CONCLUSION A history of exposure to the affected area or patient is a major cause of 2019-nCoV infection,and population clustering is a high risk factor for transmission.Patients may not necessarily have respiratory system symptoms as the only clinical manifestation but may also have concomitant or first onset digestive symptoms.Attention should be paid to the prevention and treatment of multiple organ dysfunction syndrome.Nucleic acid testing is extremely important and needs to be repeated several times.Laboratory and auxiliary exam

关键词： 2019-nCoV pneumonia Acute exacerbation of chronic obstructive pulmonary disease epidemiological investigation Clinical manifestations Integrated Chinese and Western medicine treatment

Ocular biometry in the adult population in rural central China: a population-based, cross-sectional study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2015年第4期8卷 812-817页

作者： Ting Fu Yin-Wei Song Zhi-Qi Chen Jun-Wen He Kun Qiao Xu-Fang Sun Hong Zhang Jun-Ming Wang Department of Ophthalmology Tongji Hospital Tongji Medical College Huazhong University of Science and Technology

·AIM: To describe the distribution and determinants of ocular biometric parameters and to ascertain the relative importance of these determinants in a large population of adults in rural central China.·METHODS: A population-based, cross-sectional study performed in rural central China included 1721 participants aged 40 or more years. Ocular biometrical parameters including axial length(AL), anterior chamber depth(ACD), radius of corneal curvature(K) and horizontal corneal diameter [white-to-white(WTW)distance] were measured using non-contact partial coherence interferometry [intraocular lens(IOL)-Master].·RESULTS: Ocular biometric data on 1721 participants with a average age of 57.0 ±8.7y were analyzed at last.The general mean AL, ACD, mean corneal curvature radius(MCR), WTW were 22.80±1.12, 2.96±0.36, 7.56±0.26 and 11.75 ±0.40 mm, respectively. The mean values of each parameter in 40 to 49, 50 to 59, 60 to 69, and 70 to91 years age groups were as follows: AL, 22.77 ±0.87,22.76 ±1.06, 22.89 ±1.41, 22.92 ±0.80 mm; ACD, 3.10 ±0.32,2.98 ±0.34, 2.86 ±0.36, 2.77 ±0.35 mm; MCR, 7.58 ±0.25,7.54 ±0.26, 7.55 ±0.26, 7.49 ±0.28 mm; WTW, 11.79 ±0.38,11.75 ±0.40, 11.72 ±0.41, 11.67 ±0.41 mm. The AL, ACD,MCR and WTW were correlated with age and the AL was correlated with height and weight.·CONCLUSION: Our findings can serve as an important normative reference for multiple purposes and may help to improve the quality of rural eye care.

关键词： epidemiological investigation axial length anterior chamber depth Chinese population