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Seldom-segment versus multi-segment intramedullary spinal cord gliomas: a comparative clinical study

Science China(Life Sciences) 2019年第6期62卷 862-864页

作者： Jianjun Sun Zhenyu Wang Zhendong Li Haibo Wu Mei Zheng Qing Chang Yunfeng Han Zhihui Cui Hung I Liao Tao Wang Xiaodong Chen Xuan Yang Jun Yang Department of Neurosurgery Peking University Third Hospital Beijing 100191 China Department of Neuroradiology Peking University Third Hospital Peking University Beijing 100191 China Department of Neurology Peking University Third Hospital Peking University Beijing 100191 China Department of Pathology Peking University Third Hospital Peking University Beijing 100191 China Institute of Laboratory Medicine Fuzhou General Hospital of Nanjing Military Command Fuzhou 350025 China Department of Internal Medicine Wyckoff Heights Medical Center Brooklyn NY 11237 USA Eye Center Beijing Tongren Hospital Capital Medical University Beijing 100730 China

Dear Editor,Glial tumors (80%), astrocytomas, and ependymomas are the most frequent histological types of intramedullary spinal cord tumors (Bansal et al., 2013). Intramedullary tumors spanning three or more vertebral body levels are considered multi-segment intramedullary spinal cord tumors and have a much lower incidence than less involved tumors (Wang et al., 2012). We prospectively studied 81 consecutive patients who underwent resection of intramedullary spinal cord gliomas at a single medical center (The Neurosurgery Department of Peking University Third Hospital) between January 2010 and December 2015 to compare the neurological function and prognosis of patients with seldom-segment and multiple-segment intramedullary spinal cord gliomas.

关键词： Glial tumors ependymomas intramedullary spinal

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MISME Syndrome:A Case Report Of Neurofibromatosis Type-2

MISME Syndrome:A Case Report Of Neurofibromatosis Type-2

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中国中西医结合学会神经外科专业委员会第一届学术大会暨神经外科专业委员会成立大会

作者： Jin Xin He Junhua Vang Dingkun Zhang Xinwen Wu Ye Liu Hanjiang Wu Zhangyi Jin Jun Luo Neurosurgery Department Zhejiang Provincial Tongde Hospital Department of Neurology Temple University School of Medicine

Mnemonic MISME syndrome is a rare neurofibromatosis type-2(NF2) for multiple inherited schwannomas,meningiomas,and *** is an autosomal dominantly inherited disorder due to mutations of a tumor-suppressor gene on the chromosome *** it is characterized by multiple benign tumors arising in both the central and the peripheral nervous system,particularly from the bilateral vestibulocochlear nerve in more than 90%of the patients with NF2 and more than two thirds of them develop spinal tumors,which are often devastating and difficult to *** occurrence of triple tumors in an NF2 patient is ***,simultaneous occurrence of the triple tumors in a shared common location is even *** reported here a young woman with MISME syndrome with triple tumors affecting the cervical spinal cord in whom staging microsurgical resection intervention produced a clinically favorable *** reports with immunochemical staining showed the presence of schwannomas,meningiomas,and *** claimed that surgical debulking on those symptomatic craniospinal tumors is the option of treatment of the *** microsurgical techniques may reduce adverse outcomes.

关键词： MISME syndrome Neurofibromatosis type 2 craniospinal tumors staging operation microsurgery schwannomas meningiomas ependymomas

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Microsurgery of intramedullary cervical cord tumor

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中华医学杂志(英文版) 1996年第10期109卷 761-761页

作者： Xu Qiwu Bao Weimin Mao Renling Department of Neurosurgery Institute of Neurology Shanghai Medical University Shanghai 200040

OBJECTIVE To evaluate whether intramedullary tumor of the cervical spinal cord is amenable to aggressive surgery and to clarify surgical timing and important points for tumor *** AND METHODS Fifty-eight patients with intramedullary tumor of the cervical spinal cord were examined by magnetic resonance imaging and treated by microsurgery in Huashan Hospital between May 1988 and December 1994. The results were analysed by F or Chi square *** Tumors were totally resected in 50 cases (86.2%), subtotally resected in 7 and partially resected in 1. Forty-five (77.6%) patients had their neurological status improved postoperatively. Most patients with moderate neurological deficit can recover remarkably after total tumor removal. Laser surgery is especially helpful for treating *** Intramedullary tumor of the cervical spinal cord is amenable to total tumor removal. Operation is suitable when a patient presents moderate neurological deficit. Proficient surgical technique and standards for total tumor resection are essential for goodRESULTS . Preoperative radiotherapy contributes to difficult surgery and poor prognosis, and is not recommended.

关键词： SPINAL-CORD ependymomas CHILDREN

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