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Annular pancreas associated with duodenal carcinoma

World Journal of Gastroenterology 2010年第25期16卷 3206-3210页

作者： Enrico Bronnimann Silke Potthast Tatjana Vlajnic Daniel Oertli Oleg Heizmann Depart-ment of Surgery University of Basel CH-4031 Basel Switzerland Institute of Diagnostic Radiology University Hospital Basel CH-4031 Basel Switzerland Institute of Pathology University of Basel CH-4031 Basel Switzerland

Annular pancreas (AP) is a rare congenital anomaly. Coexisting malignancy has been reported only in a few cases. We report what is, to the best of our knowledge, the first case in the English literature of duodenal adenocarcinoma in a patient with AP. In a 55-year old woman with duodenal outlet stenosis magnetic resonance cholangiopancreatography showed an aberrant pancreatic duct encircling the duodenum. Duodenojejunostomy was performed. Eight weeks later she presented with painless jaundice. Duodenopancreatectomy revealed a duodenal adenocarcinoma, surrounded by an incomplete AP. Thus, co-existent malignancy with AP can be present without obstructive jaundice and without being visible through preoperative diagnostics.

关键词： duodenal carcinoma Annular pancreas Duodenopancreatectomy Whipples operation

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Helical tomotherapy for duodenal adenocarcinoma in an elderly patient: A case report

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World Journal of Gastrointestinal Oncology 2017年第2期9卷 94-97页

作者： Valentina Lancellotta Giuseppe Russo Marco Lupattelli Martina Iacco Elisabetta Perrucci Claudio Zucchetti Lorenzo Falcinelli Cynthia Aristei Radiation Oncology Section Department of Surgical and Biomedical Sciences University of Perugia Perugia General Hospital Gastroenterology Division Perugia General Hospital Radiation Oncology Division Perugia General Hospital Medical Physics Unit Perugia General Hospital

To evaluate the efficacy and feasibility of external beam radiotherapy(EBRT) for duodenal adenocarcinoma in an 84-year-old female who underwent EBRT(2.2 Gy/d for a total dose of 46.2 Gy) using helical tomotherapy(HT). Toxicity was evaluated on the National Cancer Institute's common toxicity criteria(CTCAE 3.0). The patient completed the treatment without G3-G4 toxicity. After 22-mo follow-up, she is alive and well, in complete remission with no late side effects. HT seems to be feasible and effective for duodenal adenocarcinoma in old to very old patients.

关键词： The elderly duodenal carcinoma Helical tomotherapy Toxicity

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Adenocarcinoma of the third duodenal portion:Case report and review of literature

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World Journal of Gastrointestinal Surgery 2012年第1期4卷 23-26页

作者： Federico Sista Giuseppe De Santis Antonio Giuliani Emanuela Marina Cecilia Federica Piccione Laura Lancione Sergio Leardi Gianfranco Amicucci General Surgery Department of SurgeryUniversity of L’Aquila

We focus on the diagnostic and therapeutic problems of duodenal adenocarcinoma, reporting a case and reviewing the literature. A 65-year old man with adenocarcinoma in the third duodenal portion was successfully treated with a segmental resection of the third part of the duodenum, avoiding a duodeno-cephalo-pancreatectomy. This tumor is very rare and frequently affects the III and IV duodenal portion. A precocious diagnosis and the exact localization of this neoplasia are crucial factors in order to decide the surgical strategy. Given a non-specificity of symptoms, endoscopy with biopsy is the diagnostic gold standard. Duodeno-cephalo-pancreatectomy (DCP) and segmental resection of the duodenum (SRD) are the two surgical options, with overlapping morbidity (27% vs 18%) and post operative mortality (3% vs 1%). The average incidence of postoperative long-term survival is 100%, 73.3% and 31.6% of cases after 1, 3 and 5 years from surgery, respectively. Long-term survival is made worse by two factors: the presence of metastatic lymph nodes and tumor localization in the proximal duodenum. The two surgical options are radical: DCP should be used only for proximal localizations while SRD should be chosen for distal localizations.

关键词： duodenal carcinoma Duodeno-cephalo-pancreatectomy Segmental resection Survival III duodenal portion duodenal embryological development

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