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Endoscopic ultrasound evaluation in the surgical treatment of duodenal and peri-ampullary adenomas

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World Journal of Gastroenterology 2013年第4期19卷 511-515页

作者： Lilian C Azih Brett L Broussard Milind A Phadnis Martin J Heslin Mohamad A Eloubeidi Shayam Varadarajulu Juan Pablo Arnoletti Department of General Surgery University of Alabama BirminghamBirminghamAL 35233United States Department of Biostatistics Kansas University Medical CenterKansas CityKS 66160United States Department of Surgical Oncology University of Alabama BirminghamBirminghamAL 35233United States Department of Gastroenterology American University of BeirutBeirut 1107 2020Lebanon Department of Gastroenterology the Center for Specialized Surgery at Florida HospitalOrlandoFL 32804United States Department of Surgical Oncology The Center for Specialized Surgery at Florida HospitalOrlandoFL 32804United States

AIM:To investigate endoscopic ultrasound(EUS) for predicting depth of mucosal invasion and to analyze outcomes following endoscopic and transduodenal ***:Records of 111 patients seen at our institution from November 1999 to July 2011 with the postoperative pathological diagnosis of benign ampullary and duodenal adenomas were *** of patients who underwent preoperative EUS for diagnostic purposes were *** accuracy of EUS in predicting the absence of muscular invasion was assessed by comparing EUS reports to the final surgical pathological *** addition,the incidence of the post-operative complications over a period of 30 d and the subsequent long-term outcome(recurrence) over a period of 30 mo associated with endoscopic and transduodenal surgical resection was recorded,compared and ***:Among 111 patients with benign ampullary and duodenal adenomas,47 underwent preoperative EUS for 29 peri-ampullary lesions and 18 duodenal *** addition,computed tomography was performed in 18 patients,endoscopic retrograde cholangio-pancreatography in 10 patients and esophagogastroduodenoscopy in 22 *** were 43 patients with sporadic adenomas and 4 patients with familial adenomatous polyposis(FAP)/other polyposis *** 38(81%,P duodenal ampullectomy with sphincteroplasty in 10 cases and pancreaticoduodenectomy in 6 *** main post-operative final pathological results included villous adenoma(n = 5),adenoma(n =

关键词： Endoscopic ultrasound duodenal periampullary adenoma Esophagogastroduodenoscopy Cholangio-pancreatography

To be or not to be:The host genetic factor and beyond in Helicobacter pylori mediated gastro-duodenal diseases

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World Journal of Gastroenterology 2015年第10期21卷 2883-2895页

作者： Dipanjana Datta De Susanta Roychoudhury R and D Division (Genetics) School of Human Genetics and Population Health Cancer Biology and Inflammatory Disease Division Indian Institute of Chemical Biology

Helicobacter pylori(***)have long been associated with a spectrum of disease outcomes in the gastroduodenal *** in bacterial virulence factors or strains is not enough to explain the divergent disease phenotypes manifested by the *** review focuses on host genetic factors that are involved during infection and eventually are thought to influence the disease *** have summarizedthe different host genes that have been investigated for association studies in *** mediated duodenal ulcer or gastric *** discuss that as the bacteria co-evolved with the host;these host gene also show much variation across different ethnic *** illustrate the allelic distribution of interleukin-1B,across different population which is one of the most popular candidate gene studied with respect to *** ***,we highlight that several polymorphisms in the pathway gene can by itself or collectively affect the acid secretion pathway axis(gastrin:somatostatin)thereby resulting in a spectrum of disease

关键词： Helicobacter pylori Gastric cancer duodenal ulcer

Endoscopic fibrin sealant closure of duodenal perforation after endoscopic retrograde cholangiopancreatography

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World Journal of Gastroenterology 2015年第45期21卷 12976-12980页

作者： Hsin-Yeh Yang Jui-Hao Chen Division of Gastroenterology Department of Internal Medicine Shin Kong Wu Ho-Su Memorial Hospital Faculty of Medicine Taipei Medical University

Traditionally, perivaterian duodenal perforation can be managed conservatively or surgically. If a large volume of leakage results in fluid collection in the retroperitoneum, surgery may be necessary. Our case met the surgical indication for perivaterian duodenal perforation after endoscopic retrograde cholangiopancreatography(ERCP) with sphincterotomy and endoscopic papillary balloon dilatation. The patient developed a retroperitoneal abscess after the procedures, and a perivaterian perforation was suggested on computed tomography(CT). CT-guided abscess drainage was performed immediately. We unsuccessfully attempted to close the perforation with hemoclips initially. Subsequently, we used fibrin sealant(Tisseel) injection to occlude the perforation. Fibrin sealant injections have been previously used during endoscopy for wound closure and fistula repair. Based on our report, fibrin sealant injection can be considered as an alternative method for the treatment of ERCPrelated type Ⅱ perforations.

关键词： Perivaterian duodenal perforation Endoscopic retro

Successful treatment of life-threatening bleeding from a duodenal posterior bulb peptic ulcer by an over-the-scope-clip

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World Journal of Gastroenterology 2015年第5期21卷 1666-1669页

作者： Thorsten Brechmann Wolff Schmiegel Department of Gastroenterology and Hepatology Berufsgenossenschaftliches Universit?tsklinikum Bergmannsheil Gmb HRuhr-University Bochum44789 BochumGermany

Bleeding of peptic ulcer at the posterior duodenal bulb still is a particular endoscopic challenge with increased risk of treatment failure and worse *** this article,we report successful treatment of an actively bleeding peptic ulcer located at the posterior duodenal wall,using an over-the-scope-clip in the case of a 54-year-old male patient with hemorrhagic *** primary hemostasis was achieved and no adverse events occurred during a follow-up of 60 d.

关键词： Over-the-scope-clip duodenal ulcer Upper gastroint

Successful balloon-occluded retrograde transvenous obliteration for bleeding duodenal varices using cyanoacrylate

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World Journal of Gastroenterology 2013年第6期19卷 951-954页

作者： Rintaro Hashimoto Keitaro Sofue Yoshito Takeuchi Kentaro Shibamoto Yasuaki Arai Department of Diagnostic Radiology National Cancer Center Central Hospital

A 76-year-old woman with hepatitis C cirrhosis presented with tarry stools and *** endoscopy demonstrated bleeding duodenal varices in the second portion of the ***-enhanced computed tomography revealed markedly tortuous varices around the wall in the *** afferent veins appeared to have developed,and the right ovarian vein draining into the inferior vena cava was detected as an efferent ***-occluded retrograde transvenous obliteration (BRTO) of the varices using cyanoacrylate was successfully performed in combination with the temporary occlusion of the portal *** no previous publications have used cyanoacrylate as an embolic agent for BRTO to control bleeding duodenal varices,this strategy can be considered as an alternative procedure to conventional BRTO using ethanolamine oleate when numerous afferent vessels that cannot be embolized are present.

关键词： Bleeding duodenal varices Balloon-occluded retrograde transvenous obliteration Cyanoacrylate Combination therapy Temporary portal vein occlusion

Endoscopic drainage for duodenal hematoma following endoscopic retrograde cholangiopancreatography: A case report

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World Journal of Gastroenterology 2013年第13期19卷 2118-2121页

作者： Ya-Min Pan Tian-Tian Wang Jun Wu Bing Hu Department of Endoscopy Eastern Hepatobiliary HospitalSecond Military Medical University

Intramural duodenal hematoma (IDH) is a rare complication following endoscopic retrograde cholangiopancreatography (ERCP). Blunt damage caused by the endoscope or an accessory has been suggested as the main reason for IDH. Surgical treatment of isolated duodenal hematoma after blunt trauma is traditionally reserved for rare cases of perforation or persistent symptoms despite conservative management. Typical clinical symptoms of IDH include abdominal pain and vomiting. Diagnosis of IDH can be confirmed by imaging techniques, such as magnetic resonance imaging or computed tomography and upper gastrointestinal endoscopy. duodenal hematoma is mainly treated by drainage, which includes open surgery drainage and percutaneous transhepatic cholangial drainage, both causing great trauma. Here we present a case of massive IDH following ERCP, which was successfully managed by minimally invasive management: intranasal hematoma aspiration combined with needle knife opening under a duodenoscope.

关键词： duodenal hematoma duodenal obstruction Endoscopic retrograde cholangiopancreatography Non-operative method

Mechanisms involved in Helicobacter pylori induced duodenal ulcer disease:an overview

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World Journal of Gastroenterology 2000年第5期6卷 619-623页

作者： Lars Olbe Lars Fndriks Annika Hamlet Ann-Mari Svennerholm Ann-Catrin Thoreson Centre for Gastroenterological Research University of GteborgSweden

duodenal ulcer (DU) can be developed viaseveral different *** ofgastric acid is,however,a common *** hypersecretion of acid can by itself evoke aDU,*** the Zollinger-Ellison *** of the mechanism behind thedevelopment ... 详细信息

关键词： Helicobacter pylori Helicobacter infection gastric acid gastric mucosa duodenal ulcer bicarbonates gastric metaplasia

Short-and long-term outcomes of endoscopically treated superficial non-ampullary duodenal epithelial tumors

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World Journal of Gastroenterology 2019年第6期25卷 707-718页

作者： Yuko Hara Kenichi Goda Akira Dobashi Tomohiko Richard Ohya Masayuki Kato Kazuki Sumiyama Takehiro Mitsuishi Shinichi Hirooka Masahiro Ikegami Hisao Tajiri Department of Endoscopy The Jikei University School of Medicine Department of Gastroenterology Dokkyo Medical University Department of Endoscopy The Jikei University Katsushika Medical Center Department of Pathology The Jikei University School of Medicine Department of Innovative Interventional Endoscopy Research The Jikei University School of Medicine

BACKGROUND It is widely recognized that endoscopic resection(ER) of superficial nonampullary duodenal epithelial tumors(SNADETs) is technically challenging and may carry high risks of intraoperative and delayed bleeding and *** adverse events could be more critical than those occurring in other levels of the gastrointestinal tract. Because of the low prevalence of the disease and the high risks of severe adverse events, the curability including short-and long-term outcomes have not been standardized *** To investigate the curability including short-and long-term outcomes of ER for SNADETs in a large case *** This retrospective study included cases that underwent ER for SNADETs at our university hospital between March 2004 and July 2017. Short-term outcomes of ER were measured based on en bloc and R0 resection rates as well as adverse events. Long-term outcomes included local recurrence detected on endoscopic surveillance and disease-specific mortality in patients followed up for ≥ 12 mo after *** In the study, 131 patients with 147 SNADETs were analyzed. The 147 ERs consisted of 136 endoscopic mucosal resections(EMRs)(93%) and 11 endoscopic submucosal dissections(ESDs)(7%). The median tumor diameter was 10 *** pathology diagnosis was adenocarcinoma(56/147, 38%), high-grade intraepithelial neoplasia(44/147, 30%), or low-grade intraepithelial neoplasia(47/147, 32%). The R0 resection rate was 68%(93/136) in the EMR group and73%(8/11) in the ESD group, respectively. Cap-assisted EMR(known as EMR-C)showed a higher rate of R0 resection compared to the conventional method of EMR using a snare(78% vs 62%, P = 0.06). No adverse event was observed in the EMR group, whereas delayed bleeding, intraoperative perforation, and delayed perforation in 3, 3, and 5 patients occurred in the ESD group, respectively. One patient with perforation required emergency surgery. In the 43 mo median follow-up period, local recurrence was found in four EMR

关键词： duodenal adenoma duodenal cancer Endoscopic resection Endoscopic submucosal dissection Long-term outcome

Success and safety of endoscopic treatments for concomitant biliary and duodenal malignant stenosis: A review of the literature

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World Journal of Gastrointestinal Surgery 2019年第2期11卷 53-61页

作者： Benedetto Mangiavillano Mouen A Khashab Ilaria Tarantino Silvia Carrara Rossella Semeraro Francesco Auriemma Mario Bianchetti Leonardo Henry Eusebi Chen Yen-I Luca De Luca Mario Traina Alessandro Repici Gastrointestinal Endoscopy Unit Humanitas-Mater Domini Humanitas Huniversity Division of Gastroenterology and Hepatology Johns Hopkins Hospital Gastroenterology and Endoscopy Unit Mediterranean Institute for Transplantation and Advanced Specialized Therapies (IsMeTT) Digestive Endoscopy Unit Division of Gastroenterology Humanitas Clinical and Research Center IRCCS Digestive Endoscopy Unit Istituto Clinico Humanitas Research Hospital Unit of Gastroenterology Department of Medical and Surgical Sciences S. Orsola-Malpighi Hospital University of Bologna Gastroenterology and Digestive Endoscopy Unit Ospedali Riuniti Marche Nord Digestive Endoscopy Unit Division of Gastroenterology Humanitas Research Hospital

Synchronous biliary and duodenal malignant obstruction is a challenging endoscopic scenario in patients affected with ampullary, peri-ampullary, and pancreatic head neoplasia. Surgical bypass is no longer the gold-standard therapy for these patients, as simultaneous endoscopic biliary and duodenal stenting is currently a feasible and widely used technique, with a high technical success in expert hands. In recent years, endoscopic ultrasonography(EUS) has evolved from a diagnostic to a therapeutic procedure, and is now increasingly used to guide biliary drainage, especially in cases of failed endoscopic retrograde cholangiopancreatography(ERCP). The advent of lumen-apposing metal stents(LAMS) has expanded EUS therapeutic options, and changed the management of synchronous bilioduodenal stenosis. The most recent literature regarding endoscopic treatments for synchronous biliary and duodenal malignant stenosis has been reviewed to determine the best endoscopic approach, also considering the advent of an interventional EUS approach using LAMS.

关键词： Malignant biliary strictures Malignant duodenal stenosis Bilio-duodenal stenosis Biliary self-expandable metal stent duodenal self-expandable metal stent Lumen-apposing metal stents Gastro-jejunostomy