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检索条件"主题词=Dual targeting"
9 条 记 录,以下是1-10 订阅
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dual-targeting prodrug nanotheranostics for NIR-Ⅱfluorescence imaging-guided photo-immunotherapy of glioblastoma
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Acta Pharmaceutica Sinica B 2022年 第9期12卷 3486-3497页
作者: Fenglin Li Yi Lai Jiayi Ye Madiha Saeed Yijing Dang Zhifeng Zou Fangmin Chen Wen Zhang Zhiai Xu School of Chemistry and Molecular Engineering East China Normal UniversityShanghai 200241China State Key Laboratory of Drug Research&Center of Pharmaceutics Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China
Glioblastoma(GBM) therapy is severely impaired by the blood-brain barrier(BBB) and invasive tumor growth in the central nervous system.To improve GBM therapy,we herein presented a dual-targeting nanotheranostic for se... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Both metaxin and Tom20 together with two mitochondria-specific motifs support mitochondrial targeting of dual-targeting AtSufE1
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Journal of Integrative Plant Biology 2022年 第8期64卷 1596-1613页
作者: Seungjin Woo Byeongho Moon Inhwan Hwang Department of Life Sciences Pohang University of Science and TechnologyPohang 790‐784Korea
Plant cells have two endosymbiotic organelles,chloroplasts,and mitochondria.These organelles perform specific functions that depend on organelle-specific proteins.The majority of chloroplast and mitochondrial proteins... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Engineering a folic acid-decorated ultrasmall gemcitabine nanocarrier for breast cancer therapy: dual targeting of tumor cells and tumor-associated macrophages
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Acta Pharmaceutica Sinica B 2022年 第3期12卷 1148-1162页
作者: Pearl Moharil Zhuoya Wan Apurva Pardeshi Jiang Li Haozhe Huang Zhangyi Luo Sanjay Rathod Ziqian Zhang Yuang Chen Bei Zhang Christian A.Fernandez Jingjing Sun Song Li Center for Pharmacogenetics Department of Pharmaceutical ScienceSchool of PharmacyUniversity of PittsburghPA 15261USA
Combination of passive targeting with active targeting is a promising approach to improve the therapeutic efficacy of nanotherapy.However,most reported polymeric systems have sizes above100 nm,which limits effective e... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
dual targeting of a Mitochondrial Protein: The Case Study of Cytochrome C1
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Molecular Plant 2011年 第4期4卷 679-687页
作者: Anja Rodiger Bianca Baudisch Uwe Langner Ralf Bernd Klosgen Institute of Biology--Plant Physiology Martin Luther University Halle-Wittenberg Weinbergweg 10 06120 Halle/Saale Germany
As a result of the endosymbiotic gene transfer, the majority of proteins of mitochondria and chloroplasts is encoded in the nucleus and synthesized in the cytosol as precursor molecules carrying N-terminal transit pep... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
dual targeting to Mitochondria and Chloroplasts: Characterization of Thr-tRNA Synthetase targeting Peptide
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Molecular Plant 2009年 第6期2卷 1298-1309页
作者: Anna-Karin Berglund Erika Spanning Henrik Biverstahl Gianluca Maddalo Christian Tellgren-Roth Lena Maler Elzbieta Glaser Department of Biochemistry and Biophysics Arrhenius Laboratories for Natural Science Stockholm University SF-10691 Stockholm Sweden Department of Genetics and Pathology Rudbecklaboratoriet Uppsala University SE-751 85 Uppsala Sweden
There is a group of proteins that are encoded by a single gene, expressed as a single precursor protein and dually targeted to both mitochondria and chloroplasts using an ambiguous targeting peptide. Sequence analysis... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
dual targeting of a Processing Peptidase into Both Endosymbiotic Organelles Mediated by a Transport Signal of Unusual Architecture
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Molecular Plant 2012年 第2期5卷 494-503页
作者: Bianca Baudisch Ralf Bernd Klosgen Institute of Biology-Plant Physiology Martin Luther University Halle-Wittenberg Weinbergweg 10 06120 Halle/Saale Germany
As a result of the endosymbiotic gene transfer, the majority of proteins of mitochondria and chloroplasts are encoded in the nucleus and synthesized in the cytosol as precursor proteins carrying N-terminal transport s... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Import Determinants of Organelle-Specific and dual targeting Peptides of Mitochondria and Chloroplasts in Arabidopsis thaliana
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Molecular Plant 2014年 第1期7卷 121-136页
作者: Changrong Ge Erika Spanning Elzbieta Glaser Ake Wieslander Department of Biochemistry and Biophysics Center for Biomembrane Research Stockholm University SE-106 91 Stockholm Sweden Medical Inflammation Research Department of Medical Biochemistry and Biophysics Karolinska Institute SE-171 77 Stockholm Sweden
Most of the mitochondrial and chloroplastic proteins are synthesized in the cytosol as precursor proteins carrying an N-terminal targeting peptide (TP) directing them specifically to a correct organelle. However, th... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Temperature-sensitive polypeptide brushes-coated mesoporous silica nanoparticles for dual-responsive drug release
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Chinese Chemical Letters 2019年 第12期30卷 2291-2294页
作者: Yahan Cui Rong Deng Xiangshuai Li Xinghuo Wang Qiong Jia Emilie Bertrand Kamel Meguellati Ying-Wei Yang International Joint Research Laboratory of Nano-Micro Architecture Chemistry(NMAC) College of ChemistryJilin UniversityChangchun 130012China Key Laboratory of Polymer Ecomaterials Changchun Institute of Applied ChemistryChinese Academy of ScienceChangchun 130022China
A biopolymer-inorganic hybrid system(MSN@PBLGF) is designed and fabricated from mesoporous silica nanoparticles(MSNs) and folic acid(FA)-terminated temperature-sensitive synthetic polypeptide,i.e.,poly(γ-benzyl-L-glu... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
The Arabidopsis Protein CGLD11 Is Required for Chloroplast ATP Synthase Accumulation
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Molecular Plant 2016年 第6期9卷 885-899页
作者: Sabine Grahl Bennet Reiter Irene Luise Gugel Evgenia Vamvaka Chiara Gandini Peter Jahns Jurgen Soil Dario Leister Thilo Ruhle Lehrstuhl fur Biochemie und Physiologie der Pflanzen (Botanik) Department Biologie I Ludwig-Maximilians-Universitat Munchen 82152 Planegg-MartinsriedGermany Lehrstuhl for Molekularbiologie der Pflanzen (Botanik) Department Biologie I Ludwig-MaximHians-Universitat MQnchen 82152 Planegg-Martinsried Germany Plant Biochemistry Heinrich-Heine-University DLisseldorf Universittsstrasse 1 40225 Desseldorf Germany Munich Centre for Integrated Protein Science CiPSM Ludwig-Maximilians Universitat Menchen Butenandtstr. 5 - 13 81377 Munich Germany These authors contributed equally to this article.
ATP synthases in chloroplasts (cpATPase) and mitochondria (mtATPase) are responsible for ATP production during photosynthesis and oxidative phosphorylation, respectively. Both enzymes consist of two multi- subunit... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论