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Efficacy of different antibiotics in treatment of children with respiratory mycoplasma infection

World Journal of Clinical Cases 2021年第23期9卷 6717-6724页

作者： Mei-Ying Zhang Yan Zhao Jin-Feng Liu Guo-Ping Liu Rui-Yun Zhang Li-Min Wang Department of Pediatrics Qingdao Municipal HospitalQingdao 266011Shandong ProvinceChina Department of ICU Jinan City People’s HospitalJinan 271199Shandong ProvinceChina Department of Interventional Radiology Affiliated Hospital of Qingdao UniversityQingdao 266003Shandong ProvinceChina

BACKGROUND Respiratory infections in children are common pediatric diseases caused by pathogens that invade the respiratory *** are considerably susceptible to Mycoplasma pneumoniae *** has been widespread clinical attention on treatment strategies for this *** To analyze the clinical efficacy of different antibiotics in treating pediatric respiratory mycoplasma *** We included 106 children with a confirmed diagnosis of respiratory mycoplasma infection who were admitted to our hospital from April 2017 to July 2019 and grouped them using a random number *** them,53 children each received clarithromycin or *** clinical efficacy of both drugs was evaluated and *** performed the multiplex polymerase chain reaction(MP-PCR)test and determined the MP-PCR negative rate in children after the end of the treatment *** compared the incidence of toxic and side effects,including nausea,diarrhea,and abdominal pain;further,we recorded the length of hospitalization,antipyretic time,and drug ***,we evaluated and compared the compliance of the children during *** The erythromycin group showed a significantly higher total effective rate of clinical treatment than the clarithromycin ***-PCR test results showed that the clarithromycin group had a significantly higher MP-PCR negative rate than the erythromycin ***,children in the clarithromycin group had shorter fever time,shorter hospital stays,and lower drug costs than those in the erythromycin *** clarithromycin group had a significantly higher overall drug adherence rate than the erythromycin *** incidence of toxic and side effects was significantly lower in the clarithromycin group than in the erythromycin group(P<0.05).CONCLUSION Our findings indicate that clarithromycin has various advantages over erythromycin,including higher application safety,stronger mycoplasma clearance,and higher medicatio

关键词： Clarithromycin Erythromycin Mycoplasma respiratory infection Children Clinical efficacy drug compliance Toxic side effects

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The effects of information platform-based nursing on preventing venous thromboembolism in patients with hip fractures

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Chinese Journal of Traumatology 2022年第6期25卷 367-374页

作者： Yuan Gao Xiao-Jie Fu Ming-Xing Lei Peng-Bin Yin Yu-Tong Meng Qing-Mei Wang Hong-Ying Pi Nursing Department The First Medical Center of Chinese PLA GeneralBeijing100853China Department of Orthopedics The First Medical Center of Chinese PLA General HospitalBeijing100853China Department of Orthopedics Beijing ChaoYang HospitalCapital Medical UniversityBeijing100020China Health Service Training Center of PLA General Hospital Beijing100853China

Purpose:Venous thromboembolism(VTE)is a major health issue among hip fracture *** study aimed to develop an information platform based on a mobile application and then evaluate whether information platform-based nursing could improve patient’’s drug compliance and reduce the incidence of VTE in hip fracture ***:This study retrospectively analyzed hip fracture patients who were treated with conventional prevention and intervention methods for VTE(control group)between January 2008 and November 2012,and prospectively analyzed hip fracture patients who were treated with nursing intervention based on the information platform(study group)between January 2016 and September *** the patients included in the both groups were hip fracture patients who had an age over 50 years,treated with surgery,and hospitalized≥48 *** were excluded if they admitted to hospital due to old fractures,had a severe bleeding after 72 h of admission,diagnosed with any type of VTE,or refused to participate in the *** information platform was divided into medical,nursing,and patient *** on the information platform,medical practitioners and nurses could perform risk assessments,monitoring management and early warnings,preventions and treatments,health educations,follow-up,and other aspects of nursing interventions for *** study compared essential characteristics,drug compliance,VTE occurrence,and mean length of hospitalization between the two ***,a subgroup analysis was performed in the study group according to different drug *** 18.0 software(IBM Corp.,NY,and USA)was used for statistical ***:Altogether 1177 patients were included in the control group,and 491 patients in the study *** baseline data,patients in the study group had more morbidities than those in the control group(pdrug compliance between the two groups was statistically significant(p<0.001):761(64.7%)

关键词： Venous thromboembolism Hip fractures Information platform-based nursing drug compliance Risk assessment and management

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