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A preliminary study of a new high-resolution detector matrix applied to three-dimensional dose verification in intensity-modulated radiotherapy

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Radiation Medicine and Protection 2021年第3期2卷 121-127页

作者： Renchuan Zheng Along Chen Jinhan Zhu Lixin Chen Shengxiu Jiao Detao Xiao College of Nuclear Science and Technology University of South ChinaHengyangHunan421001China State Key Laboratory of Oncology in South China Sun Yat-sen University Cancer CenterGuangzhouGuangdong510060China School of Physics and Engineering Technology Sun Yat-sen UniversityGuangzhouGuangdong510275China

Objective:To test the basic dosimetry characteristics of a new high-resolution matrix and to perform a preliminary study on the three-dimensional(3D)dose verification of intensity-modulated treatment(IMRT).Methods:The dosimetry characteristics of the new matrix were investigated,including repeatability,dose-rate response,and dose *** cases of nasopharyngeal carcinoma(NPC)and 20 cases with lung cancer were randomly selected for IMRT plans,and the novel matrix was employed for 3D dose *** measured results were evaluated using the gamma passing rate(GPR)and dose volume histogram(DVH).The action limit(AL)and tolerance limit(TL)of the target volume and each organ at risk(OAR)were calculated with reference to the American Association of Physicists in Medicine(AAPM)TG218 ***:The matrix performed well for all dosimetry characteristic tests,with a deviation ofvolumes and OARs,the average GPRs were>90%under the relatively strict standard of 2%/2 *** DVH showed that the measurement results of D_(98) and D_(95) for the target volumes were slightly lower and D_(2) were higher than those of treatment planning system(TPS)(Pvolumes and OARs,especially small-volume OARs such as the chiasma and optic ***:The new matrix showed good dosimetry characteristics and can be effectively applied to the treatment planning dose verification of the head-neck and lung *** research is needed to establish how to analyze the GPR and DVH of the target volume and

关键词： Three-dimensional dose verification Gamma passing rate dose volume histogram Action limit Tolerance limit

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