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Neglected tropical diseases in Brazilian children and adolescents:data analysis from 2009 to 2013

Infectious diseases of Poverty 2017年第1期6卷 1369-1378页

作者： Eduardo Brandao Sebastian Romero Maria Almerice Lopes da Silva Fred Luciano Neves Santos National Reference Service for Filariasis Aggeu Magalhães Institute(Fiocruz-PE)RecifePernambucoBrazil Faculty of Medical Sciences National University of RosarioRosarioSanta FeArgentina Laboratory of Communicable diseases Parasitology DepartmentAggeu Magalhaes Institute(Fiocruz-PE)RecifePernambucoBrazil Laboratory of Pathology and Bio-Intervention Goncalo Moniz Institute(Fiocruz-BA)SalvadorBahiaBrazil

Background:Neglected tropical diseases(NTDs)prevail in conditions of poverty and contribute to the maintenance of social inequality.Out of the NTDs prioritized by the Brazilian Ministry of Health,four parasitic infections require mandatory notification:acute Chagas disease,leishmaniasis,malaria,and schistosomiasis.Data on the behaviour of these NTDs in the young population are currently limited.This study seeks to analyse the epidemiological aspects of these parasitic infections in children and adolescents in Brazil.Methods:A retrospective exploratory ecological study was conducted.A spatial analysis of the cases reported between 2009 and 2013 in individuals aged between 0 and 19 years that were notified through the Health notification Aggravation Information System(SINAN)was performed.Results:In total,64,567 cases of cutaneous and visceral leishmaniasis,malaria,schistosomiasis,and acute Chagas disease were recorded in the SINAN database,representing a rate of 20.15 cases per 100,000 inhabitants.The average age of the cases was 12.2 years and 62.32%were male.Four hundred and three deaths related to these obligatorily reported parasites were recorded,indicating a case fatality rate of 0.62%.Visceral leishmaniasis and acute Chagas disease had the highest rates of lethality.A heterogeneous spatial distribution of the studied parasites was observed.Conclusions:The number of cases and the lethality rate described in this study show that these diseases still represent a serious problem for public health in Brazil.This points to the need to encourage new research and the reformulation of social,economic,and public health policies aimed at ensuring better health and living conditions for all individuals,especially those among the populations considered vulnerable,as is the case of the young.

关键词： Parasites Visceral leishmaniasis Malaria Schistosomiasis Chagas disease disease notification Residence characteristics Brazil

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Brazilian Spotted Fever Mortality Profile: 2018 to 2022

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Advances in Infectious diseases 2023年第3期13卷 498-507页

作者： Danielle Satie Kassada Paula Cristina Pereira da Costa Gabriel Borba de Castro Isabela Cristina Nogueira Henrique Ceretta Oliveira Dalvani Marques Department of Public Health School of Nursing University of Campinas Sao Paulo Brazil Undergraduate Student at the School of Nursing University of Campinas Sao Paulo Brazil Master’s Student at the School of Nursing University of Campinas Sao Paulo Brazil Statistician at the School of Nursing University of Campinas Sao Paulo Brazil

Background: Spotted Fever (SF) is an acute febrile zoonosis of variable severity that typically occurs in an endemic manner with worldwide distribution. Considering that SF is a disease of significant public health importance, this study aims to identify the mortality profile due to SF in Brazil from 2018 to 2022. Methods: Quantitative and descriptive cross-sectional approach. Data were collected from Brazilian Spotted Fever (BSF) cases registered in the Notifiable diseases Information System (SINAN-DATASUS) across all regions of Brazil. The data collected includes information on the following variables: year of symptom, evolution, sex, race, environment of infection, region of notification, and age group. Subsequently, the data was entered into Microsoft Excel to create tables and graphs. The chi-square test was then applied to statistically analyze the associations between qualitative variables. A modified Poisson regression model with robust variance was constructed to analyze the age group data and determine which categories had different probabilities of death. The results show the estimates obtained for prevalence ratios, as well as their respective confidence intervals and p-values. The statistical software SAS version 9.4 was used to perform the analysis and a significance level of 5% was considered. Results: From 2018 to 2022, a total of 1126 cases of BSF were reported. Out of these cases, 59.3% (668) were cured, 32.4% (364) resulted in death, 1.1% (13) died from other causes and 7.2% (81) had no recorded outcome. Regarding the region with the highest death rate, the Southeast region led with 99.45% (362) of cases, followed by the Northeast region with 0.45% (2). As for the age group, the majority (63.7%) fell between the ages of 20 and 59 years old. In terms of race/color, 52.7% of the population identified as white. Regarding the contamination environment, 39.3% were in leisure areas. The outcome of death by BSF showed statistically significant associations with sex (p-value = 0.03) and age group (p-va

关键词： Brazilian Spotted Fever Mortality Communicable diseases disease notification

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