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Basal Cell Carcinoma Excision Guided by dermoscopy:A Retrospective Study in Macao

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International Journal of Dermatology and Venereology 2023年第3期6卷 147-149页

作者： Ricardo Coelho Si Leong Cheong Department of Dermatology Centro Hospitalar Conde de São JanuárioMacao SAR 999078China

Objective:Dermoscopic evaluation of tumor margins may help to accurately detect lateral borders before surgical excision.The purpose of this study was to comprehensively evaluate the usefulness of dermoscopically detecting basal cell carcinoma tumor margins before surgical excision.Methods:The authors retrospectively analyzed the outcomes of 60 basal cell carcinomas that were excised after undergoing dermoscopic evaluation of the margins from 2016 to 2018 in a single center in Macao SAR,China.Descriptive statistical analysis was carried out by using frequencies and percentages.Results:All treated tumors were completely excised,although five had safety margins ofdermoscopy-assisted versus conventional excision are needed to better evaluate the value of this technique.

关键词： basal cell carcinoma dermoscopy surgery

dermoscopy in China: current status and future prospective

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Chinese Medical Journal 2019年第17期132卷 2096-2104页

作者： Xue Shen Rui-Xing Yu Chang-Bing Shen Cheng-Xu Li Yan Jing Ya-Jie Zheng Zi-Yi Wang Ke Xue Feng Xu Jian-Bin Yu Ru-Song Meng Yong Cui Department of Dermatology Chengdu Second People’s Hospital Chengdu Sichuan 610017 China Department of Dermatology China-Japan Friendship Hospital Beijing 100029 China Graduate School Peking Union Medical College and Chinese Academy of Medical Sciences Beijing 100730 China Department of Dermatology The First Affiliated Hospital of Anhui Medical University Hefei Anhui 230032 China Department of Dermatology Affiliated Chaohu Hospital of Anhui Medical University Hefei Anhui 238001 China Shanghai Wheat Color Intelligent Technology Company LTD Shanghai 200051 China Department of Dermatology The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan 450052 China Department of Dermatology Specialty Medical Center of the Air Force Chinese People’s Liberation Army Beijing 100142 China

Objective: dermoscopy is a useful technique for improving the diagnostic accuracy of various types of skin disorders. In China, dermoscopy has been widely accepted, and domestic researchers have made tremendous progress in the field of dermoscopy. The main purpose of this review is to summarize the current status of dermoscopy in China and identify its future directions. Data sources: Articles included in this review were obtained by searching the following databases: Wanfang, China National Knowledge Infrastructure, PubMed, and the Web of Science. We focused on research published before 2019 with keywords including dermoscopy, dermoscopic, dermoscope and trichoscopy. Study selection: A total of 50 studies were selected. Of these studies, 20 studies were in Chinese and 30 in English, research samples of all the studies were collected from Chinese populations. Results: Since 2000, more than 380 articles about dermoscopy have been published in domestic or foreign journals. dermoscopy can improve the diagnostic accuracy of neoplastic diseases, evaluating the therapeutic effect of treatment, and determining the treatment endpoint, and it can also assist in the differential diagnosis of inflammatory diseases and in the assessment of the severity of the disease. In addition, researches about the applications of dermoscopy during surgical treatment have been published. Training courses aiming to improve the diagnostic ability of dermatologists, either face-to-face or online, have been offered. The Chinese Skin Image Database, launched in 2017 as a work platform for dermatologists, has promoted the development of dermoscopy in China. Computer-aided diagnostic systems based on the Chinese population are ready for use. In the future, cooperation, resource sharing, talent development, image management, and computer-aided diagnosis will be important directions for the development of dermoscopy in China. Conclusion: dermoscopy has been widely used and developed in China, however, it still needs to address more challenges in t

关键词： dermoscopy China Current status Future

dermoscopy Features of Trichofolliculoma: A Case Report

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International Journal of Dermatology and Venereology 2020年第3期3卷 179-181页

作者： Lu Gan Hao Chen Wei Zhang Jian-Fang Sun Department of Pathology Hospital for Skin Diseases(Institute of Dermatology)Chinese Academy of Medical Sciences and Peking Union Medical CollegeNanjingJiangsu 210042China

Introduction:Trichofolliculoma characterized clinically by the presence of acentral dilated pore with tufted hairs and corresponds histologically to a central primary follicle and many secondary vellus hair follicles originating from it.Thus far,dermoscopy dascription of trichofolliculoma has been lacking.Here,we describe a typical case of trichofolliculoma,particularly the special manifestation under the dermoscopy.Case presentation:A 29-year-old man complained a five-year history of a nodule containing a central whitish hair plug on his left tempus.Dermoscopic examination revealed a well-defined,yellow macule with a central whitish hair plug surrounded by dilated capillaries,and histopathological analysis was consistent with trichofolliculoma.Discussion:The findings of dermoscopy were also vary,which may be affected by the origin of the disease,various phases of the hair cycle,depth of the lesion,and even external stimulus.Conclusion:Diagnosis of trichofolliculoma is sometimes difficult because the presence of the central crater and visible hairs is low,and dermoscopy examination may be a potentially useful diagnostic tool.

关键词： trichofolliculoma dermoscopy case report

Scabies Evaluated by dermoscopy and Fluorescence Microscopy: A Case Report

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International Journal of Dermatology and Venereology 2021年第4期4卷 260-262页

作者： Li-Wen Zhang Wen-Ju Wang Xue-Ying Liu Lei Xu Lu Zheng Cong-Hui Li Yong-Hong Lu Department of Dermatovenereology Chengdu Second People’s HospitalChengduSichuan 610017China

Introduction: Scabies is an infectious skin disorder caused by the mite Sarcoptes scabiei. The diagnosis of scabies is often confirmed by microscopic detection of scabies mites, eggs, or feces.We herein describe the diagnosis of scabies in a boy with the assistance of dermoscopy and fluorescence microscopy.Case presentation: A 16-year-old Chinese boy presented with a 2-month history of extensive papules and excoriations with intense pruritus on the trunk and limbs. dermoscopy showed a sinuous burrow in the finger webs with a brown jet-shaped triangular structure at the end. A fluorescence microscopy revealed a hatching egg and a mite. The boy was diagnosed with scabies and treated with 5% sulfur ointment.Discussion: The use of dermoscopy in patients with scabies reveals a sinuous burrow with a brown jet-shaped triangular structure composed of the pigmented head and anterior legs of the mite[1]. A fluorescence microscopy revealed mites and eggs with blue fluorescence after staining, allowing us to easily identify scabies.Conlcusion: The combination of dermoscopy-guided tape testing with fluorescence staining technology may enhance the diagnostic accuracy and efficiency of scabies.

关键词： scabies dermoscopy fluorescence case report

Arithmetic Optimization with Ensemble Deep Transfer Learning Based Melanoma Classification

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计算机、材料和连续体（英文） 2023年第4期75卷 149-164页

作者： K.Kalyani Sara A Althubiti Mohammed Altaf Ahmed ELaxmi Lydia Seifedine Kadry Neunggyu Han Yunyoung Nam Department of Computer Science Dr.Nalli Kuppusamy Arts College(Affiliated to Bharathidasan UniversityTiruchirappalli)Thanjavur613003India Department of Computer Science College of Computer and Information SciencesMajmaah UniversityAl-Majmaah11952Saudi Arabia Lepartment of Computer Engineering College of Computer Engineering&SciencesPrince Sattam Bin Abdulaziz UniversityAl-Kharj11942Saudi Arabia Department of Computer Science and Engineering Vignan’s Institute of Information TechnologyVisakhapatnam530049India Department of Applied Data Science Noroff University CollegeKristiansandNorway Department of ICT Convergence Soonchunhyang UniversityKorea

Melanoma is a skin disease with high mortality rate while earlydiagnoses of the disease can increase the survival chances of patients. Itis challenging to automatically diagnose melanoma from dermoscopic skinsamples. Computer-Aided Diagnostic (CAD) tool saves time and effort indiagnosing melanoma compared to existing medical approaches. In this background,there is a need exists to design an automated classification modelfor melanoma that can utilize deep and rich feature datasets of an imagefor disease classification. The current study develops an Intelligent ArithmeticOptimization with Ensemble Deep Transfer Learning Based MelanomaClassification (IAOEDTT-MC) model. The proposed IAOEDTT-MC modelfocuses on identification and classification of melanoma from dermoscopicimages. To accomplish this, IAOEDTT-MC model applies image preprocessingat the initial stage in which Gabor Filtering (GF) technique is utilized.In addition, U-Net segmentation approach is employed to segment the lesionregions in dermoscopic images. Besides, an ensemble of DL models includingResNet50 and ElasticNet models is applied in this study. Moreover, AOalgorithm with Gated Recurrent Unit (GRU) method is utilized for identificationand classification of melanoma. The proposed IAOEDTT-MC methodwas experimentally validated with the help of benchmark datasets and theproposed model attained maximum accuracy of 92.09% on ISIC 2017 dataset.

关键词： Skin cancer deep learning melanoma classification dermoscopy computer aided diagnosis

Malignant form of hidroacanthoma simplex:A case report

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世界临床病例杂志 2023年第24期11卷 5804-5810页

作者： Yi-Fei Yang Rong Wang Hui Xu Wei-Guo Long Xiao-Hui Zhao Yu-Mei Li Department of Dermatology The Affiliated Hospital of Jiangsu UniversityZhenjiang 212001Jiangsu ProvinceChina Department of Pathology The Affiliated Hospital of Jiangsu UniversityZhenjiang 212001Jiangsu ProvinceChina

BACKGROUND This paper presents a case of malignant hidroacanthoma simplex(HAS)and review the literature of previous cases to summarize the histopathological and immunohistochemical features and display the dermoscopic features of malignant HAS.CASE SUMMARY We present an 88-year-old Asian female with malignant HAS.The diagnosis was made according to the histopathological and immunohistochemical results after biopsy.Previous case reports of malignant HAS were retrieved from PubMed to characterize the histopathological and immunohistochemical features.We also display the dermoscopic features of malignant HAS that have not been reported.CONCLUSION Our findings demonstrate that prompt surgical treatment is an effective strategy for malignant HAS.Histopathology and immunohistochemistry are valuable diagnostic tools.This is the first case report to display the dermoscopic features of malignant HAS,and we speculate that dermoscopy may contribute to the diagnosis of malignant HAS.

关键词： Malignant hidroacanthoma simplex dermoscopy Immunohistochemistry Histopathology Diagnosis Case report

Dermoscopic Assessment of Pityriasis Versicolor:A Cross-Sectional Observational Study

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International Journal of Dermatology and Venereology 2023年第3期6卷 130-135页

作者： Navakumar Manickam Praveen Vasanthi Saminathan Deepika Vazhavanthan Kannan Gopalan Department of Skin&STD Vinayaka Mission’s Kirupananda Variyar Medical College&HospitalVinayaka Mission’s Research Foundation(deemed to be University)SalemTamil Nadu 636308India

Objective:Pityriasis versicolor(PV)is usually a clinical diagnosis.In uncertain cases,PV is confirmed by microscopic examination with 10%potassium hydroxide(KOH).However,the KOH test is not 100%sensitive in diagnosing PV.dermoscopy of PV is still an unexplored area with very little data reported.This study was planned to study the various dermoscopic features and their utility in the diagnosis of PV.Methods:This cross-sectional observational study was carried out over a 1-year period(September 2020-September 2021)among 57 patients with KOH-confirmed PV.All patients underwent dermoscopy using a handheld dermoscope(DermLite DL4;DermLite LLC).The chi-square test or Fisher’s exact test was used to analyze the data.Results:Of the 57 patients,43(75.44%)had the hypopigmented type,followed by the hyperpigmented type(n=12,21.05%)and the perifollicular type(n=2,3.51%).Nonuniform pigmentation was the most common dermoscopic finding observed in both patients with hypopigmented PV(n=42,97.67%)and hyperpigmented PV(n=12,100%)(P=0.001).Scaling was the second most commonly observed finding;patchy scaling(n=25,58.13%)and perifollicular scaling(n=13,30.23%)were commonly seen in hypopigmented PV,while hyperpigmented PV showed more diffuse scaling(n=6,50.00%)(P=0.04)followed by patchy scaling(n=5,41.66%).dermoscopy showed unique“double-edged scales”in all lesions with furrow scaling(n=11,19.30%)after eliciting a positive evoked scale sign.Other interesting features seen in hypopigmented PV were hypopigmentation around the hair follicle(n=24,55.48%)(P=0.001)and perilesional hyperpigmentation(the halo sign)(n=15,34.88%)(P=0.04).Conclusion:We observed several dermoscopic findings in PV that can serve as useful clues for differentiating PV from other similar disorders.

关键词： dermoscopy hypopigmented hyperpigmented pityriasis versicolor tinea versicolor

Dermoscopic Assessment of Lymphangioma Circumscriptum Treated With Topical Sirolimus Ointment:A Case Report

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International Journal of Dermatology and Venereology 2023年第4期6卷 236-238页

作者： Balachandra Suryakant Ankad Sankappanavara Veeranna Smitha Sushila Nagur Department of Dermatology S.Nijalingappa Medical CollegeBagalkotKarnataka 587102India

Introduction:Lymphangioma circumscriptum (LC) is characterized by malformation of superficial lymphatics.dermoscopy reveals brownish-yellow lacunae and white septa.In scrotal LC,gray and red areas are also noted.Treatment of LC is challenging because of its high recurrence.Case presentation:A male patient presented with fluid-filled lesions on the scrotum after partial penectomy.Examination revealed multiple skin-colored vesicles containing serous fluid on either side of the scrotum.dermoscopy showed brownish-yellow lacunae with white septa as specific patterns.A diagnosis of secondary LC was made based on the clinical and dermoscopic features,and the patient was treated with 0.1% topical sirolimus ointment.Discussion:Management of LC includes close follow-up.Sirolimus,by inhibiting cellular proliferation and angiogenesis,helps in the regression of vesicular lesions of LC.Furthermore,dermoscopy supports an accurate evaluation of the therapeutic response.Conclusion:Sirolimus is a promising topical agent in the treatment of LC.dermoscopy comes handy in the evaluation of treatment response.Any residual lesions could be noted and treated accordingly.

关键词： dermoscopy lymphangioma circumscriptum sirolimus

Dermoscopic Features of Basal Cell Carcinoma and Their Association with Histological Types in A Chinese Population:A Perspective Study

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International Journal of Dermatology and Venereology 2022年第2期5卷 68-74页

作者： Shi-Qi Wang Jie Liu Tao Qu Kai Fang Hong-Zhong Jin Department of Dermatology State Key Laboratory of Complex Severe and Rare DiseasesPeking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeNational Clinical Research Center for Dermatologic and Immunologic DiseasesBeijing 100730China.

Objective:The treatments and prognoses of high-risk and low-risk basal cell carcinomas are quite different.This study aimed to examine the dermoscopic features of basal cell carcinomas and assess the association between the features and basal cell carcinomas recurrence risks in a Chinese population.Methods:Patients with histopathologically confirmed basal cell carcinomas examined from March 2016 to April 2020 were enrolled.The dermoscopic features were evaluated,and the correlations between these features and the histological types and recurrence risks were assessed.Results:The study cohort comprised 119 Chinese patients with a total of 119 skin lesions.The most common dermoscopic feature of basal cell carcinomas was the absence of a pigment network(119/119,100%),followed by shiny white streaks(105/119,88.24%),blue-gray ovoid nests(99/119,83.19%),multiple blue globules(78/119,65.55%),and arborizing vessels(78/119,65.55%);yellow-white structures were present in 29/119 lesions(24.37%).Leaf-like and spoke-wheel areas were significantly associated with superficial basal cell carcinomas(Pdermoscopy provides important information about basal cell carcinomas and is helpful in differentiating superficial basal cell carcinomas from other subtypes.The dermoscopic vascular structures and bluegray ovoid nests play a crucial role in evaluating the basal cell carcinomas risks preoperatively.

关键词： basal cell carcinoma dermoscopy histopathology recurrence risk skin cancer