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dental caries and first permanent molar pit and fissure morphology in 7-to 8-year-old children in Wuhan,China

International Journal of Oral Science 2012年第3期4卷 157-160页

作者： Jin-Dong Wang Xi Chen Jo Frencken Min-Quan Du Zhi Chen Key Laboratory for Oral Biomedicine of Ministry of Education School and Hospital of StomatologyWuhan UniversityWuhanChina Shenzhen Maternal and Children's Hospital ShenzhenChina Department of Global Oral Health Radboud University Nijmegen Medical CentreCollege of Dental SciencesNijmegenThe Netherlands

To obtain the caries experience and, plaque accumulation severity and pit and fissure morphology in first permanent molars in 7-8 children in Wuhan, as a reasonable prediction of caries risk and preventive attention in the future, a convenient sample of five primary schools in the vicinity of the Wuhan University School and Hospital of Stomatology was drawn. Two calibrated examiners orally examined all present grade 2 children in the classroom, using standard caries plaque and tooth morphology criteria. dental caries was scored at enamel （D2） and dentine （D3） for tooth and surface level. Independent variables were age, gender and school. Data analysis used analysis of variance and t-test. The sample comprised 1 043 7- and 8-year-olds. The prevalence of dental caries in permanent dentition was 8.7% and in primary dentition, 68.7%. Mean Decayed, Missing, Filled Teeth/S （DMFT/S） scores were 0.1 1 and . 14, respectively. Mean dmft/s scores were 2.8 and 5.0. The d-component constituted 75% of the d3mft index, while enamel carious lesions constituted 36% of the total number of carious lesions （d2,3-component）. Prevalence of medium and deep pits and fissures was 84.6%. Prevalence of medium and severe plaque accumulation was 67.4%. Prevalence of dental caries in the deciduous and permanent dentitions of 7- to 8-year-old children was high. Deed oits and fissures in high caries risk children should be sealed_

关键词： dental caries oral epidemiology plaque tooth morphology

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Diagnosis of dental caries Using Terahertz Technology

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Journal of Electronic Science and Technology 2021年第3期19卷 255-262页

作者： Nagendra Parasad Yadav Guo-Zhen Hu Zheng-Peng Yao Ashish Kumar School of Electrical and Electronics Information Engineering Hube Polytechnic UniversityHuangshi 435003 School of Electronics and Optical Engineering Nanjing University of Science and TechnologyNanjing 210094

Recently,the diagnoses of dental caries and other dental issues are in a queue as only X-ray-based techniques are available in most hospitals around the ***(THz)parametric imaging(TPI)is the latest technology that can be applied for medical applications,especially dental *** technology is harmless and thus suitable for biological samples owing to the low energy of THz *** this paper,a developed TPI system is used to investigate the two-dimensional(2 D)and three-dimensional(3D)images of different samples from human *** analyzing the measured images of human teeth,the results suggest that the THz parametric technology is capable of investigating the inner side structure of the *** technique can be useful in detecting the defects in all types of human and animal *** measurement and analytical calculations have been performed by using the TPI system and MATLAB,respectively,and both are in good *** characteristics of THz waves and their interactions with the tooth samples are *** the available THz-based technologies,such as TPI,and their potential applications of diagnoses are also presented.

关键词： dental caries early diagnosis medical application terahertz(THz)parametric imaging(TPI) three-dimensional(3D)imaging

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Adjuvant postbiotic administration improves dental caries prognosis by restoring the oral microbiota

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Food Science and Human Wellness 2024年第5期13卷 2690-2702页

作者： Qing Liu Teng Ma Cuijiao Feng Yalin Li Hao Jin Xuan Shi Lai-Yu Kwok Yan Shi Tingtao Chen Heping Zhang Affiliated Stomatological Hospital of Nanchang University Nanchang 330000China Department of Endodontics Affiliated Stomatological Hospital of Nanchang UniversityThe Key Laboratory of Oral Biomedicine of Jiangxi ProvinceJiangxi Province Clinical Research Center for Oral DiseasesNanchang 330000China Inner Mongolia Key Laboratory of Dairy Biotechnology and Engineering Inner Mongolia Agricultural UniversityHohhot 010000China Key Laboratory of Dairy Products Processing Ministry of Agriculture and Rural AffairsInner Mongolia Agricultural UniversityHohhot 010000China Key Laboratory of Dairy Biotechnology and Engineering Ministry of EducationInner Mongolia Agricultural UniversityHohhot 010000China National Engineering Research Center for Bioengineering Drugs and the Technologies Institute of Translational MedicineNanchang UniversityNanchang 330000China

Conventional filling therapy fails to fundamentally reduce oral cariogenic ***,oral microbiota follow-up intervention after filling would be necessary for improving dental caries *** recruited 9 caries-free individuals,and 89 dental caries subjects(5 dropouts).Eighty-nine patients were randomized into three groups:caries(n=8;no treatment),control(n=40;filling),and postbiotics(n=41;filling and 14-day Probio-Eco®intervention).Salivary samples were collected at 0 day(after filling)and 14 *** results showed that the diversity of dental caries oral microbiota was significantly increased compared with healthy subjects,and filling could restore a healthier oral microbiota partially and *** intervention keeps a low ***-occurrence network analysis showed that a more stable oral microbiota structure after postbiotics *** and functional annotation of the microbiota revealed that postbiotics co-treatment significantly:increased the relative abundance of Pseudomonas and ***,decreased the relative abundance of Prevotella shahii,and enriched the energy metabolism-related ***-predicted phenotypes inferred to an oral microbiota with decreased potential pathogenic bacteria and increased oxidative stress-tolerant bacteria after postbiotics ***,it suggested that postbiotics co-treatment could be a promising strategy that restores the oral microecological balance for dental caries.

关键词： Postbiotics Oral microbiota Salivary microbiota dental caries Pacific Biosciences(PacBio)single molecule real-time(SMRT)sequencing dental filling

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Progress toward understanding the contribution of alkali generation in dental biofilms to inhibition of dental caries

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International Journal of Oral Science 2012年第3期4卷 135-140页

作者： Ya-Ling Liu Marcelle Nascimento Robert A Burne Depa rtment of Oral Biology College of Dent stry University of Florida Gainesville USA Department of Restorative dental Sciences Division of Operative Dentistry College of Dentistry University of Florida Gainesville USA

Alkali production by oral bacteria is believed to have a major impact on oral microbial ecology and to be inibitory to the initiation and progression of dental caries. A substantial body of evidence is beginning to accumulate that indicates the modulation of the alkalinogenic potential of dental biofilms may be a promising strategy for caries control. This brief review highlights recent progress toward understanding molecular genetic and physiologic aspects of important alkali-generating pathways in oral bacteria, and the role of alkali production in the ecology of dental biofilms in health and disease.

关键词： arginine biofilm dental caries microbial ecology urea

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The Epidemic Tendency of dental caries Prevalence of School Students from 1991 to 2005 in China

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2010年第1期30卷 132-137页

作者：唐杰余毅震马颖 Department of Child and Maternal Care School of Public HealthTongji Medical CollegeHuazhong University of Science and Technology

The epidemic tendency of dental caries of school students over the past 15 years in China was analyzed in order to provide bases for prevention of dental *** sets of boys and girls at the age of 7,9,12 years(deciduous caries)and 7,9,12,14,17 years(permanent caries)were collected from the series of Chinese National Surveillance on Students Constitution and Health(CNSSCH)between 1991 to 2005,a survey that covers 30 provinces of and autonomous regions of China,with Tibet Autonomous Region and Taiwan P...

关键词： dental caries dental caries rate dynamic analysis China

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Toward dental caries: Exploring nanoparticle-based platforms and calcium phosphate compounds for dental restorative materials

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Bioactive Materials 2019年第1期4卷 43-55页

作者： Abdulrahman A.Balhaddad Anmar A.Kansara Denise Hidan Michael D.Weir Hockin H.K.Xu Mary Anne S.Melo Ph.D.Program in Biomedical Sciences University of Maryland School of DentistryBaltimoreMD21201USA Division of Biomaterials&Tissue Engineering Department of Advanced Oral Sciences and TherapeuticsUniversity of Maryland School of DentistryBaltimoreMD21201USA Department of Restorative dental Sciences Imam Abdulrahman Bin Faisal UniversityCollege of DentistryDammamSaudi Arabia Department of Restorative Dentistry Umm Al-Qura UniversityCollege of DentistryMakkahSaudi Arabia Division of Operative Dentistry Dept.of General DentistryUniversity of Maryland School of DentistryBaltimoreMD21201USA

Millions of people worldwide suffer from a toothache due to tooth cavity,and often permanent tooth *** caries,also known as tooth decay,is a biofilm-dependent infectious disease that damages teeth by minerals loss and presents a high incidence of clinical restorative polymeric fillings(tooth colored fillings).Until now,restorative polymeric fillings present no *** complexity of oral biofilms contributes to the difficulty in developing effective novel dental *** has been explored in the development of bioactive dental materials to reduce or modulate the activities of caries-related ***-structured platforms based on calcium phosphate and metallic particles have advanced to impart an anti-caries potential to restorative *** bioactivity of these platforms induces prevention of mineral loss of the hard tooth structure and antibacterial activities against caries-related *** has been suggested that this bioactivity could minimize the incidence of caries around restorations(CARS)and increase the longevity of such filling *** last few years witnessed growing numbers of studies on the preparation evaluations of these novel ***,the caries disease process and the role of pathogenic caries-related biofilm,the increasing incidence of CARS,and the recent efforts employed for incorporation of bioactive nanoparticles in restorative polymer materials as useful strategies for prevention and management of caries-related-bacteria are *** highlight the status of the most advanced and widely explored interaction of nanoparticle-based platforms and calcium phosphate compounds with an eye toward translating the potential of these approaches to the dental clinical reality.

关键词： dental materials Bioactive Nanoparticles dental caries

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Relationships between daily total fluoride intake and dental fluorosis and dental caries

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Journal of Nanjing Medical University 2009年第1期23卷 33-39页

作者： Quanyong Xiang Minghao Zhou Ming Wu Xinya Zhou Li Lin Jiuning Huan Youxing Liang Jiangsu Province Center for Disease Control and Prevention Nanjing 210009 China Suqian Center for Disease Control and Prevention Suqian 223800 China Department of Occupational Health School of Public Health Fudan University Shanghai 200032 China

Objective： To explore the relationships between the daily total intake of fluoride, dental fluorosis and dental caries. Methods： An epidemiological method was used to investigate the daily total intake of fluoride, dental fluorosis, and dental caries among 236 and 290 children aged 8-13 years in a severe endemic area and in a non-fluorosis control area, respectively. The children were divided into eight subgroups according to each child＇ s estimated daily total intake of fluoride. The prevalence of dental fluorosis and dental caries in each group was calculated. Results： As expected, elevated levels of fluoride intake were significantly associated with a higher prevalence of dental fluorosis and an increasing amount of more severe defect dental fluorosis. When the daily total F intake was 2.78 mg/child/day, the prevalence of dental fluorosis was nearly 100%, with the prevalence of defect dental fluorosis increasing with increasing fluoride intake. There was also a significant negative（inverse） dose-response relationship between the daily total intake of fluoride and the overall prevalence of dental caries, the prevalence of which decreased when the daily total intake of fluoride increased up to 3.32 mg/child/day. However, at higher levels of daily total intake of fluoride the prevalence of dental caries increased, giving rise to a U-shaped dose-response relationship curve. Conclusion： It is important to monitor total fluoride exposure and protect children from excessive fluoride intake, especially during the years of tooth development.

关键词： Fluoride Daily total fluoride intake dental fluorosis dental caries

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Assessment of dental caries and Oral Hygiene Status Among Twins

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Journal of Forensic Science and Medicine 2018年第1期4卷 18-22页

作者： Priya Subramaniam K L Girish Babu Bharath Vardhana Department of Pedodontics and Preventive Dentistry The Oxford Dental College and HospitalBengaluru1Departmentof DentistryHassan Institute of Medical SciencesHassanKarnatakaIndia

The study of twins provides a unique opportunity to evaluate the genetic and nongenetic contributions to a variance of multitude of *** research has revealed the impact of a strong genetic component to the variance of many dental *** present study was conducted to assess the dental caries and oral hygiene status in monozygotic(MZ)and dizygotic(DZ)twins.A random sample of 129 MZ and DZ twin pairs aged 6-15 years were included in this *** zygosity of twin pairs was initially recorded by facial appearance and later determined by *** caries and oral hygiene status were recorded in these twin pairs and the data were subjected to statistical *** significant difference was observed in the mean decayed,extracted due to caries and filled teeth(deft)in primary dentition and decayed,missing and filled(DMFT)in permanent dentition scores and oral hygiene status in MZ and DZ twin pair&The similarity observed in oral health status reflects the effects of a shared environment in MZ and DZ twin pairs.

关键词： dental caries dermatoglyphics facial appearance oral hygiene index-simplified zygosity

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Quantitative detection of Streptococcus mutans and bacteria of dental caries and no caries groups in permanent teeth from a north China population

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Chinese Medical Journal 2012年第21期125卷 3880-3884页

作者： WANG Zhan-yong WANG Jian-qiu ZHOU Yan ZHAO Dong XIAO Bai Laboratory Research Center Department of Dentistry Beijing-Chao-Yang Hospital CapitalMedical University Beijing 100020 China

Background Streptococcus mutans （S. mutans） is the prime pathogen of dental caries. There are few reports that studied the relationship between S. mutans, bacteria and dental caries in permanent teeth when compared to those in primary teeth. This study aimed to detect S. mutans and bacteria of dental caries and non-caries groups in permanent teeth from a north China population by real-time polymerase chain reaction （PCR） and compare the relationship between the number of these bacteria and the prevalence of dental caries in permanent teeth.

关键词： real-time polymerase chain reaction, streptococcus mutans dental caries

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Prevalence of dental caries among preschool children in Shanghe County of Shandong Province and relevant prevention and treatment strategies

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Chinese Medical Journal 2008年第22期121卷 2246-2249页

作者： SHANG Xiao-hong LI Da-lu HUANG Yi CHEN Hui SUN Ruo-peng Department of Pediatrics Jinan Central Hospital Affiliated to Shandong University Jinan Shandong 250013 China Department of Oral and Maxillofacial Surgery Stomatological Hospital of Jinan Jinan Shandong 250001 China Department of Stomatology Maternity and Children's Hospital of Jinan Jinan Shandong 250001 China Department of Operative Dentistry and Endodontics Stomatological Hospital of Jinan Jinan Shandong 250001 China Department of Pediatrics Qilu Hospital of Shandong University Jinan Shandong 250012 China

Background Decayed teeth are harmful to children＇s growth and development and can severely jeopardize their health. This study was set out to investigate and analyze the prevalence of dental caries in preschool children in Shanghe County in Shandong Province, China, and provide new insights into potential prevention and treatment strategies. Methods Based on the random sampling method, we performed dental examinations of children aged 2 to 6 years in kindergartens of Shanghe County. The prevalence of caries, the average number of decayed teeth per capita as well as the constituent rates of decayed, missing and filled teeth were determined retrospectively. SPSS software was used for data analysis. Results dental caries were found in 1088 out of 2052 children from 56 kindergartens. The total number of decayed teeth was 4487 with a prevalence of 53.02%. The average number of decayed teeth per capita was 2.187, and the filling rate was 0.29%. There was no statistical difference in the prevalence of caries between boys and girls though there were significant differences between different age groups. The prevalence of decayed teeth as well as the mean number of decayed teeth infected per capita increased with age. In addition, urban children had a higher prevalence than those from rural areas （P 〈0.01）. Conclusions The prevalence of decayed caries among kindergarten children in Shanghe County was high, suggesting that more emphasis should be put on improving oral health education with priority given to prevention. Further efforts should be made to increase the decayed caries filling rate.

关键词： decayed, missing and filled teeth dental caries oral health preschool child prevalence," preventive dentistry

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