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densiron 68 heavy silicone oil in the management of inferior retinal detachment recurrence: analysis on functional and anatomical outcomes and complications

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International Journal of Ophthalmology(English edition) 2019年第4期12卷 615-620页

作者： Tomaso Caporossi Fabrizio Franco Lucia Finocchio Francesco Barca Fabrizio Giansanti Ruggero Tartaro Gianni Virgili Stanislao Rizzo Department of Translational Surgery and Medicine Ophthalmology University of Florence Azienda Ospedaliero-Universitaria Careggi

AIM: To assess the efficacy and safety of a heavy silicone oil(densiron 68) in the management of inferior retinal detachment ***: A retrospective non-comparative consecutive case series study. Forty-nine cases of complex inferior retinal detachment were treated using densiron 68 heavy silicone oil(HSO) as the endotamponade. Our main purpose was anatomic reattachment following densiron 68 removal. Functional outcomes, rate of recurrences, the presence of inflammatory complications and intraocular pressure alterations were evaluated. RESULTS: Forty-nine patients affected by complex retinal re-detachment were recruited. The mean follow-up was 7.6(±1.5) mo. The mean best corrected visual acuity after densiron 68 removal was 0.95 log MAR, standard error(SE: 0.068). Retinal reattachment was 61.2% after first surgery and 81.6% after second surgery. Nineteen cases(38.8%) had recurrences when intraocular heavy silicon oil was in situ, 26.3%(5 cases) of which involved the inferior retina. CONCLUSION: densiron 68 efficiently fills the inferior retinal periphery and might lower the risk of inferior proliferative vitreoretinopathy development, in particular after a standard silicon oil tamponade that reduces the proliferative process in the upper quadrants of the retina.

关键词： vitrectomy complex retinal detachment proliferative vitreoretinopathy ocular endo-tamponade heavy silicone oil densiron 68

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Comparison of densiron 68 and 1 000 cSt silicone oil in the management of rhegmatogenous retinal detachment with inferior breaks

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International Journal of Ophthalmology(English edition) 2013年第1期6卷 81-84页

作者： Ibrahim Kocak Haci Koc Nisa Hastanesi Fatih cadCobancesme mah Ozel Kent Hastanesi

AIM:To compare success rates and complications of densiron 68 and 1000cSt silicone oil (SO) in the management of rhegmatogenous retinal detachment (RRD) with inferior breaks (IBs). METHODS:Totally 61 eyes of 61 consecutive patients with RRD with IBs were assigned to pars plana vitrectomy (PPV) with densiron (n =31) or PPV with SO (n=30) in order of presentation. SO and densiron removal was performed 3 months after initial surgery. Follow up visits were terminated 6 months after SO removal. ·RESULTS:With a single operation, the densiron group showed 84% and SO 74% reattachment. With further surgery, both groups showed 90% reattachment. Complications such as cataract, raised intraocular pressure (IOP), inflammatory reaction, macular epiretinal membranes, and emulsification of SO were seen in both groups. CONCLUSION:densiron and SO are found to have similar success rates and complications.

关键词： retinal detachment silicone oil densiron heavy silicone oil inferior break

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高密度硅油(densiron)作为复杂视网膜脱离眼内填充物的首次应用

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世界核心医学期刊文摘（眼科学分册） 2006年第10期2卷 41-42页

作者： SandnerD. Engelmann K. 王静波 Department of Ophthalmology Medical Faculty Carl Gustav CarusUniversity of Technology DresdenFetscherstrasse 7401307 DresdenGermany

Background:In this study,we evaluated the anatomic and functional outcome and intraocular adverse effects after a 3-month endotamponade with densiron 68,a mixture of F6H8 with silicone oil,in complex inferior ***:Forty-eight eyes of 48 patients aged 27-82 years with retinal redetachment due to proliferative vitreoretinopathy(PVR)grades CP1 to CA7 were *** duration of the densiron endotamponade was 108.7± 66.9 days,with a mean followup after removal of 102.8± 31.9 ***:Twenty-two patients(45.8%)showed stable retinal reattachment after densiron *** patients(29.2%)developed retinal re-detachment after removal,generally within 1 month and in the upper circumference(n=8).In 11 patients(22.9%)recurrent re-detachment(inferior n=8)appeared during densiron *** one eye(2.1%)treatment was primarily *** acuity improved from mean logMAR 1.66± 1.03 to 1.47± 0.97(not statistically significant,P=0.257).Side effects included temporary inflammatory reaction(n=10),fibrin accumulation(n=6),sterile hypopyon(n=2),vitreous hemorrhage(n=6),elevated IOP(n=5),emulsification(n=4)and chronic hypotony(n=4).Conclusion:The anatomical success rate without further interventions of 45.8%(22 of 48 patients)seems ***,in evaluating the potential of densiron,it should be considered that all patients in this study had previous surgery with standard procedures,including silicone oil,which had already *** laser photocoagulation of the periphery of the upper quadrants might reduce the risk of retinal re-detachments.

关键词：视网膜脱离 densiron 视网膜复位低眼压玻璃体积血激光光凝研究评价前房积脓方复炎

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玻璃体切割联合重硅油眼内填充术治疗高度近视黄斑裂孔视网膜脱离的疗效评估

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中华实验眼科杂志 2015年第2期33卷 171-174页

作者：佘海澄段安丽齐越首都医科大学附属北京同仁医院北京同仁眼科中心北京市眼科学与视觉科学重点实验室北京100730

背景高度近视黄斑裂孔视网膜脱离较一般孔源性视网膜脱离的手术成功率低,玻璃体切割联合重硅油眼内填充术的治疗效果已有报道,但结果不一. 目的观察玻璃体切割联合重硅油眼内填充术治疗高度近视黄斑裂孔视网膜脱离的疗效.方法采用回... 详细信息

背景高度近视黄斑裂孔视网膜脱离较一般孔源性视网膜脱离的手术成功率低,玻璃体切割联合重硅油眼内填充术的治疗效果已有报道,但结果不一. 目的观察玻璃体切割联合重硅油眼内填充术治疗高度近视黄斑裂孔视网膜脱离的疗效.方法采用回顾性病例分析的研究方法,对2007年9月至2009年12月于首都医科大学附属北京同仁医院接受玻璃体切割联合重硅油眼内填充术的高度近视黄斑裂孔视网膜脱离患者20例20眼的临床资料进行分析.所有患眼均接受20G玻璃体切割、内界膜剥除联合重硅油填充术治疗.术中根据情况剥除黄斑前膜,必要时联合视网膜切开、眼内激光治疗,晶状体混浊者同时行白内障超声乳化联合人工晶状体植入术.术后患者自由选择体位,经睫状体平坦部行重硅油取出术,以重硅油取出术后视网膜完全复位为手术成功的标准.术眼的主要观察指标包括LogMAR视力、眼压、视网膜复位情况及并发症.结果患者术前平均等效球镜度为（-14.3±3.0）D,其中7眼为复发性视网膜脱离,占35％,7眼合并脉络膜脱离,占35％.接受玻璃体切割联合重硅油填充术后视网膜复位占95％（19/20）,一次手术视网膜复位者占90％（18/20）,二次手术后视网膜复位者占5％（1/20）,1眼经二次手术后仍有局限性视网膜脱离.术眼LogMAR视力由术前的2.77±0.81增加到术后的1.22±0.46,差异有统计学意义（P=0.000）.术中未行白内障摘出术的术眼术后均出现不同程度的晶状体后囊膜混浊,术后2眼发生非一过性眼压升高. 结论玻璃体切割联合重硅油眼内填充术后患者视力改善,术后对患者体位无特殊要求,可有效治疗高度近视黄斑裂孔视网膜脱离.

关键词：视网膜脱离高度近视 densiron 68 玻璃体切割术黄斑裂孔

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