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Predicting dementia Risk Factors Based on Feature Selection and Neural Networks

Computers, Materials & Continua 2023年第5期75卷 2491-2508页

作者： Ashir Javeed Ana Luiza Dallora Johan Sanmartin Berglund Arif Ali Peter Anderberg Liaqat Ali Aging Research Center Karolinska InstitutetStockholm17165Sweden Department of Health Blekinge Institute of TechnologyKarlskrona37141Sweden School of Health Sciences University of SkövdeSkövdeSE 54128Sweden Department of Computer Science University of Science and Technology BannuBannu28100Pakistan Department of Electrical Engineering University of Science and Technology BannuBannu28100Pakistan

dementia is a disorder with high societal impact and severe consequences for its patients who suffer from a progressive cognitive decline that leads to increased morbidity,mortality,and *** there is a consensus that dementia is a multifactorial disorder,which portrays changes in the brain of the affected individual as early as 15 years before its onset,prediction models that aim at its early detection and risk identification should consider these *** study aims at presenting a novel method for ten years prediction of dementia using on multifactorial data,which comprised 75 *** are two automated diagnostic systems developed that use genetic algorithms for feature selection,while artificial neural network and deep neural network are used for dementia *** proposed model based on genetic algorithm and deep neural network had achieved the best accuracy of 93.36%,sensitivity of 93.15%,specificity of 91.59%,MCC of 0.4788,and performed superior to other 11 machine learning techniques which were presented in the past for dementia *** identified best predictors were:age,past smoking habit,history of infarct,depression,hip fracture,single leg standing test with right leg,score in the physical component summary and history of TIA/*** identification of risk factors is imperative in the dementia research as an effort to prevent or delay its onset.

关键词： dementia prediction feature selection genetic algorithm neural networks

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