检索结果-南通市图书馆

Survival outcomes of patients with cervical esophageal cancer who received definitive radiotherapy:a retrospective study conducted in a single institution

引用

Oncology and Translational Medicine 2020年第4期6卷 135-142页

作者： Jing Wang Fei Liu Yingying Wu Lei Zhou Guangyuan Hu Lin Yang Department of Oncology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Objective Cervical esophageal cancer(CEC)is a relatively rare condition,with limited treatment *** current study aimed to assess the survival outcomes of patients with CEC who received definitive *** In total,63 consecutive patients with CEC who received definitive radiotherapy between 2010 and 2018 were included in this *** survival outcomes were analyzed based on *** The median progression-free survival(PFS)and overall survival(OS)of the patients were 12 and 19 months,*** were no significant differences in terms of survival outcomes between the groups who received radiation doses≥60 andradiotherapy was well tolerated,and no significant differences were observed in terms of treatment-related toxicities between the groups who received radiation doses≥60 and<60 *** The survival outcomes of patients with CEC should be *** proximal CEC,a radiation dose≥60 Gy is significantly correlated with better PFS,OS,and ***,further research must be performed to validate this finding.

关键词： cervical esophageal cancer definitive radiotherapy survival outcomes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Long-term follow-up of volumetric modulated arc therapy in definitive radiotherapy for cervical cancer: A single-center retrospective experience

引用

Radiation Medicine and Protection 2020年第2期1卷 81-87页

作者： Yidi Yuan Jing You Weihu Wang Xiaofan Li Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Department of Radiation Oncology Peking University Cancer Hospital and InstituteBeijingChina

Objective:To evaluate the treatment outcomes and toxicity of volumetric modulated arc therapy(VMAT)in definitive radiotherapy for patients with cervical ***:Medical records of 440 patients with cervical cancer treated with VMAT in definitive radiotherapy with or without concurrent chemotherapy between January 2010 and June 2015 in our institution were retrospectively reviewed.A dose of 45 Gy was prescribed to the planning target volume with VMAT in 25 fractions,followed by high-dose rate intracavitary brachytherapy with 28–36 Gy in 4–6 *** time was estimated using Kaplan-Meier *** factors for treatment failure were identified using Cox proportional hazards regression ***:The median follow-up periods were 58.3 months(range:2.7–112.9 months).The 3-and 5-year survival rates were overall survival(OS)79.4%and 74.4%,cancer-specific survival(CSS)81.4%and 77.1%,progressionfree survival(PFS)73.3%and 71.1%,locoregional control(LC)83.3%and 82%and distant metastasis-free survival(DMFS)80.8%and 77.7%,*** 5-year OS for patients with different stages was IB191.6%,IB2100%,IIA 82.5%,IIB 74.4%,IIIA 57.1%,IIIB 61.7%and IVB 17.6%,*** the 124 patients with recurrence,93 patients(75.0%)experienced distant *** analysis showed that non-squamous cell carcinoma of the cervix(Pdefinitive radiotherapy resulted in satisfactory outcomes with acceptable toxicities for patients with cervical *** metastasis predominated as the pattern of disease *** studies are needed to investigate the intensified systemic therapies.

关键词： Volumetric modulated arc therapy Cervical cancer definitive radiotherapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：