检索结果-南通市图书馆

Correlation between a Change of Drug Resistance of <i>Klebsiella pneumonia</i>and defined daily doses of Antimicrobial Agents from 2014 to 2018

引用

Pharmacology & Pharmacy 2020年第11期11卷 299-305页

作者： Jiuli Hu Xu Xiao Chanchan Hu Rui Wang Yanwu Zhao Xiaoqin Zhu Affiliated Hospital of ChengdeMedical University Chegnde Hebei China

Introduction: The prevalence of Klebsiella pneumoniae has rapidly increased in recent years and the distribution differed greatly by region, We aimed to study the relationship between antibiotic resistance and K. pneumoniae, especially carbapenem-resistant Klebsiella pneumoniae (CRKP) in our tertiary hospitals from 2014 to 2018. Methodology: The antibiotic consumption data of K. pneumoniae were expressed as the defined daily dose (DDD) per 100 inpatient days (DDDs). K. pneumoniae which isolated from clinical samples in hospital between January 2014 and December 2018 were retrospectively analyzed, and the correlation between antibiotic resistance rate and antibiotic frequency was analyzed. Results: From 2014 to 2018, a total of 2295 strains of K. pneumoniae were isolated, with the detection rates of 8.2%, 9.2%, 11.9%, 13.4% and 14.0%. There were 423 strains of CRKP, with the detection rates of 7.5%, 5.8%, 17.8% 24.2% and 25.2% respectively.

关键词： Klebsiella pneumonia Antibiotic Consumption Resistance Correlation Analysis defined daily doses

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Clinical pharmacists’ involvement in carbapenem antibiotics management at Wenzhou Integrated Hospital

引用

World Journal of Clinical Cases 2023年第30期11卷 7302-7308页

作者： Xue-Mei Xu Cai-Yu Pan Da-Li Zeng Department of Pharmacy Wenzhou Integrated Traditional Chinese and Western Medicine HospitalWenzhou 325000Zhejiang ProvinceChina

BACKGROUND Carbapenem antibiotics are a pivotal solution for severe infections,particularly in hospital *** emergence of carbapenem-resistant bacteria owing to the irrational and extensive use of carbapenems underscores the need for meticulous management and rational *** pharmacists,with their specialized training and extensive knowledge,play a substantial role in ensuring the judicious use of *** study aimed to elucidate the patterns of carbapenem use and shed light on the integral role played by clinical pharmacists in managing and promoting the rational use of carbapenem antibiotics at Wenzhou Integrated Traditional Chinese and Western Medicine *** To analyze carbapenem use patterns in our hospital and role of clinical pharmacists in managing and promoting their rational *** We performed a retrospective analysis of carbapenem use at our hospital between January 2019 and December *** key indicators,including the drug utilization index,defined daily doses(DDDs),proportion of antimicrobial drug costs to total hospitalization expenses,antibiotic utilization density,and utilization rates in different clinical departments were comprehensively *** Between 2019 and 2021,there was a consistent decline in the consumption and sales of imipenem-cilastatin sodium,meropenem(0.3 g),and meropenem(0.5 g).Conversely,the DDDs of imipenem-cilastatin sodium for injection increased in 2020 and 2021 vs 2019,with a B/A value of 0.67,indicating a relatively higher drug *** DDDs of meropenem for injection(0.3 g)exhibited an overall upward trend,indicating an increasing clinical ***,the B/A values for 2020 and 2021 were both>1,suggesting a relatively lower drug *** DDDs of meropenem for injection(0.5 g)demonstrated a progressive increase annually and consistently ranked first,indicating a high clinical preference with a B/A value of 1,signifying good alignment between economic and social benefits.

关键词： Clinical pharmacists Carbapenem antibiotics Rational drug use Drug utilization index defined daily doses Antibiotic utilization density

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：