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Efficacy of a Kiwifruit Extract (PhenActiv^TM) on Gastrointestinal Tract Function: A Randomised Double-Blind Placebo-Controlled Study

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Food and Nutrition Sciences 2023年第12期14卷 1281-1295页

作者： David Briskey Alistair Rowan Mallard Amanda Rao RDC Clinical Brisbane Australia School of Human Movement and Nutrition Sciences The University of Queensland Brisbane Australia School of Medicine University of Sydney Sydney Australia

Objective: Gastrointestinal (GI) discomfort is experienced by millions of people every day. This study aimed to evaluate the effect of PhenActivTM, a novel green kiwifruit extract, on gastrointestinal tract (GIT) function in otherwise healthy adults. Methods: 41 healthy adults with mild GI discomfort were enrolled in this double-blind, randomized, placebo-controlled study. Participants were randomized to either take 3.0 g/day of PhenActivTM or a placebo for 6 weeks. Interviews were conducted at baseline, week 3 and week 6, with participants completing questionnaires regarding GI symptoms. frequency of bowel movements was self-recorded daily. Results: There were no differences in daily and weekly defecation frequency and stool characteristics in either group. The active and placebo groups significantly improve GSRS scores (p , only the active group had a significant improvement in the IBSSS and PAC-QOL scores (p TM for 6 weeks did not improve defecation frequency or stool composition in healthy adults, but did improve perceived symptoms of GIT function, including symptoms of functional GIT disorders, IBS and constipation. The product was well tolerated and future trials investigating higher doses with more participants and/or a different population would be beneficial.

关键词： Kiwifruit Extract Gastrointestinal Tract Function Stool Gastrointestinal Health Bowel Function defecation frequency

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