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Soluble ADAM33 determines mechanical behaviors of airway smooth muscle cells

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医用生物力学 2013年第S1期28卷 107-108页

作者： Yiyuan Duan Jiaoyue Long Feng Lin Jun Chen Rong Xu Xuemei Jiang Linhong Deng College of Bioengineering Chongqing University Institute of Biomedical Engineering and Health Science Changzhou University

Introduction A disintegrin and metalloproteinase 33（ADAM33）has been identified as a susceptibility gene for asthma[1],In particular,ADAM33 mRNA is highly expressed in airway smooth muscle cells（ASMCs）and the level of soluble ADAM33（sADAM33）is known to inversely Correlate with lung function such as bronchial hyperresponsiveness（BHR）[2]that is ultimately determined by the mechanical behaviors of ASMCs.However,few have studied how sADAM33would affect ASMC mechanics.Here,we manipulated the expression of SADAM33 in

关键词： ADAM airway bronchial asthma cultured susceptibility Correlate ultimately integrin transmembrane

Nonalcoholic steatohepatitis and insulin resistance in children

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World Journal of Diabetes 2014年第6期5卷 917-923页

作者： Mikage Arata Junya Nakajima Shigeo Nishimata Tomomi Nagata Hisashi Kawashima Department of Pediatrics Tokyo Medical University

Various pathological conditions can cause fatty liver in children. Nonalcoholic steatohepatitis(NASH) in children has been known since 1983. However, NASH diagnosed in childhood does not have a favorable outcome.The pathological characteristics of NASH are significantly different between children and adults. Nonalcoholic fatty liver disease(NAFLD)/NASH is accompanied by insulin resistance, which plays a pivotal role in its pathophysiology in both children and adults. In NASH,a "two-hit" model involving triglyceride accumulation(first hit) and liver damage(second hit) has been accepted. Insulin resistance was found to Correlate with changes in fat levels; however, it did not Correlate with fibrosis or NAFLD activity score in children. Therefore,insulin resistance may be important in the first hit.Because there is obvious familial clustering in NASH,genetic predisposition as well as environmental factors including diet might be the second hit of NAFLD/NASH.

关键词： NASH children Correlate triglyceride familial childhood favorable accompanied pivotal Insulin

Hypertriglyceridemia and delayed clearance of fat load in transgenic animal models of mice,rabbits and minipigs expressing human ApoCⅢ

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维普期刊数据库

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中国病理生理杂志 2010年第A10期26卷 2055-2056页

作者： WANG Yu-hui1,DING Yin-yuan1,BAI Lu1,WEI Jing-yuan2,DNEG Xu-ming2,LIU Guo-ging1(1Cardiovarcular Institute,Key Laboratory of Molecular Cardiovasology for Minsitry of Education of China,Peking University,Beijing 100871,China 2College of Zootechny & Veterinary Medicine,Jilin University,Changchun 130062)

Apolipoprotein CⅢ(ApoCⅢ)has been implicated in hypertriglyceridemia and plasma ApoCⅢ is independently predicted as risk factor for coronary heart disease.Hypertriglyceridemia in patients are demonstrated to correla... 详细信息

关键词： clearance expressing transgenic lipase Correlate independently implicated hyperlipidemia cholesterol elevated

基于图像相关的Q195真实应力应变曲线研究

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清远职业技术学院学报 2018年第1期11卷 41-44页

作者：王乐平湖北汽车工业学院材料工程系湖北十堰442002

应力-应变曲线为名义应力-应变曲线,它只是一种近似曲线,对工程方面起到一个参考作用。运用图像有关计算软件GOM Correlate软件,计算薄板拉伸试样在位移载荷作用下各个阶段的应力-应变,从而得出工程应力-应变曲线以及真实应力-应变曲线... 详细信息

应力-应变曲线为名义应力-应变曲线,它只是一种近似曲线,对工程方面起到一个参考作用。运用图像有关计算软件GOM Correlate软件,计算薄板拉伸试样在位移载荷作用下各个阶段的应力-应变,从而得出工程应力-应变曲线以及真实应力-应变曲线,并对工程应力-应变和真实应力-应变进行分析。经过此方法能够有效的消除试件端面与压力机滑块和工作台之间的摩擦力对试验最终结果的影响,以及采用引伸计因安装过程中造成的误差累计。使之成为理想的单向拉伸状态并通过计算机图形学与图像处理技术,将数据转换成图形或图像在屏幕上显示出来使之可视化。该办法简便易行,普适性强且具有重要工程运用价值。

关键词：拉伸试样真实应力应变 GOM Correlate

Mutation status of epidermal growth factor receptor and KRAS gene in non-small cell long cancers at Xuanwei regions of Yunnan Province

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China Medical Abstracts(Internal Medicine) 2016年第2期33卷 34-35页

作者：杨长绍 Dept Pathol Kunming General Hosp

Objective To investigate the mutation status of epidermal growth factor receptor(EGFR)and KRAS gene in patients with non-small cell lung cancer(NSCLC)in Xuanwei,Yunnan and to Correlate the mutation status with clinico... 详细信息

关键词： Mutation mutation Correlate metastasis histological dermal gender codon smoking mutually

Self-efficacy manipulation and exercise enjoyment:age difference and analysis of Correlates

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Self-efficacy manipulation and exercise enjoyment:age differ...

Assessment of inconclusive left main coronary lesions: lessons from an intravascular ultrasound study

第16届亚洲运动会科学大会

作者： Liang Hu Shuzhi Chang Tao Yang Yanyan Zhu Peng Luo Department of Health and Sport Sciences Tianjin Institute of Physical Education

＜正＞Introduction:Research evidence has suggested that self-efficacy can be manipulated and changes in selfefficacy may have a significant influence on affective experience during and after exercise.Identifying facto... 详细信息

ISBN: (纸本)9787564405564

关键词： Exercise Happiness Self Efficacy Age differences Correlate

来源： cnki会议评论

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cnki会议

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上海医学 2007年第S1期30卷 109-109页

作者： Gary S.Mintz Stéphane G.Carlier Jose de Ribamar Costa Jr Koichi Sano Joanna Lui Giora Weisz Issam Moussa George D.Dangas Roxana Mehran Edward M.Kreps Michael Collins Gregg W.Stone Jeffrey W.Moses Junbo Ge Martin B.Leon Department of Cardiology Zhongshan HospitalFudan UniversityShanghai 200032China Columbia University Medical Center and Cardiovascular Research Foundation New YorkUSA

Objective Angiographic assessment of a left main coronary artery (LMCA) stenosis is often difficult and unreliable. Intravascular ultrasound (IVUS) assessment of absolute lumen dimensions has been shown to Correlate with fractional flow reserve (FFR) and to predict clinical outcome in patients with a LMCA stenosis. Methods During 21 months period (October, 2004 to July, 2006), 153 patients (Ostial lesions, n=47; Non-ostial lesion, n=106) underwent IVUS evaluation specifically to assess the severity of an angiographically inconclusive LMCA narrowing. IVUS analysis included plaque morphology; external elastic membrane (EEM), lumen, plaque cross-sectional areas (CSA), plaque burden (plaque CSA/ EEM) and remodeling index (lesion EEM CSA/reference EEM CSA). Results Overall, minimum lumen area (MLA) and diameter (MLD) and plaque burden measured 8.2 mm2, 2.6 mm, and 59.3 %, respectively. An MLACorrelate with a FFR <0.75) was seen 41.5% in ostial lesions and 44.5% in non-ostial lesions. In particular, ostial LMCA lesions had a larger MLA and a smaller plaque burden than non-ostial lesions (Table). Conclusions Patients referred for LMCA evaluation commonly have insignificant narrowing. Negative remodeling was prominent at the LMCA ostium. These patients deserve IVUS assessment before revascularization.

关键词： intravascular plaque remodeling stenosis burden severity lumen absolute dimensions Correlate

Relationship between estrogen receptor α and β expression and clinicopathological characteristics in elderly patients with non-small cell lung cancer

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China Medical Abstracts(Internal Medicine) 2013年第2期30卷 95-95页

作者：李琳 Dept Oncol Beijing Hosp Health Ministry

Objective To evaluate estrogen receptor(ER)α and β expressions in elderly patients with non-small cell lung cancer(NSCLC) in China and their relationship with clinical and pathological

关键词： estrogen and elderly statistically histology Correlate nucleus pression pathology stronger

THE PARTICLE VELOCITY DISTRIBUTION IN A RISER OF DILUTE CIRCULATING FLUIDIZED BED

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Chinese Journal of Chemical Engineering 1991年第2期 182-191页

作者：杨勇林金涌俞芷青汪展文白丁荣 Dept.of Chem.Eng. Tsinghua UniversityBeijing

This paper presents an experimental study on the radial and axial profiles of local particle velocity of flu-idized catalyst(FCC)particles in a circulating fluidized bed of 8000mm in height and 186mm in inside diameterwith a Fiber-Optic Probe Laser Doppler Velocimetry.It has been found that the radial profiles of local particlevelocity are parabolic,even in the centre region and steep in the region near the bed wall,and that the length ofparticle acceleration along the bed height is longer than expected.The following formula has been recommended to Correlate the 1 ocal particle velocity with dilute gas-solidflow in the bed:where a,b,c and e are functions of radial positions.

关键词： radial Probe acceleration fluidized circulating positions dilute Probability Correlate histogram