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Improving landscape connectivity through habitat restoration:application for Asian elephant conservation in Xishuangbanna Prefecture,China

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Integrative Zoology 2024年第2期19卷 319-335页

作者： Bin WAN Wenwen LI Peng LIU Nian YANG Shang CHEN Xianming GUO Bin WANG Li ZHANG Key Laboratory for Biodiversity Science and Ecological Engineering Ministry of EducationCollege of Life SciencesBeijing Normal UniversityBeijingChina Research Center for Coastal Zone Science and Marine Development Strategy First Institute of OceanographyMinistry of Natural ResourcesQingdaoChina School of Biological Sciences The University of Hong KongPokfulamHong KongChina Research Institute of Xishuangbanna National Nature Reserve JinghongChina Xishuangbanna Asian Elephant Conservation and Management Center JinghongChina

Habitat restoration is an effective method for improving landscape connectivity,which can reduce habitat fragmentation.Maintaining landscape connectivity could promote connections between habitat,which is extremely essential to preserve gene flow and population viability.This study proposes a methodological framework to analyze landscape connectivity for Asian elephant habitat conservation,aiming to provide practical options for reducing habitat fragmentation and improving habitat connectivity.Our approach involved combining a species distribution model using MaxEnt and landscape functional connectivity models using graph theory to assess the impact on connectivity improvement via farmland/plantation restoration as habitat.The results showed that:(1)there were 119 suitable habitat patches of Asian elephant covering a total area of 1952.41 km^(2).(2)The connectivity between habitats improved significantly after vegetation restoration and the gain first decreased and then increased with the increase of dispersal distance.(3)The first few new habitat patches that were identified played an important role in improving connectivity,and the variation rate of connectivity gradually leveled off as the number of new habitats increased.(4)Prioritization of the 25 best new habitat patches increased connectivity from 0.54%to 5.59%as the dispersal distance increased and mainly was located between two Asian elephant distribution regions and two components.Establishment of new habitat patches was effective for improving or restoring connectivity.Our findings can be used as guidance for improving the studied fragmented Asian elephant habitats,and they can also be used as a reference for the habitat restoration of other endangered species heavily affected by habitat fragmentation.

关键词： Asian elephant connectivity habitat restoration habitat suitability landscape graphs

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Multimodal Nature of the Single-cell Primate Brain Atlas:Morphology,Transcriptome,Electrophysiology,and connectivity

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Neuroscience Bulletin 2024年第4期40卷 517-532页

作者： Yuhui Shen Mingting Shao Zhao-Zhe Hao Mengyao Huang Nana Xu Sheng Liu State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangdong Provincial Key Laboratory of Ophthalmology and Visual ScienceGuangzhou510060China Guangdong Province Key Laboratory of Brain Function and Disease Guangzhou510080China

Primates exhibit complex brain structures that augment cognitive function.The neocortex fulfills high-cognitive functions through billions of connected neurons.These neurons have distinct transcriptomic,morphological,and electrophysiological properties,and their connectivity principles vary.These features endow the primate brain atlas with a multimodal nature.The recent integration of next-generation sequencing with modified patch-clamp techniques is revolutionizing the way to census the primate neocortex,enabling a multimodal neuronal atlas to be established in great detail:(1)single-cell/single-nucleus RNA-seq technology establishes high-throughput transcriptomic references,covering all major transcriptomic cell types;(2)patch-seq links the morphological and electrophysiological features to the transcriptomic reference;(3)multicell patch-clamp delineates the principles of local connectivity.Here,we review the applications of these technologies in the primate neocortex and discuss the current advances and tentative gaps for a comprehensive understanding of the primate neocortex.

关键词： Neuron Brain atlas Patch-seq connectivity Primate

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A divergent pattern in functional connectivity: a transdiagnostic perspective

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Neural Regeneration Research 2024年第9期19卷 1885-1886页

作者： Lu Zhang Lorenzo Pini Padova Neuroscience Center Universitàdegli Studi di PadovaPadovaItaly

Functional magnetic resonance imaging(fMRI)is a popular tool used to investigate not only how the brain responds to specific stimuli during sensorimotor or cognitive tasks,but also brain activity at rest.The physics b... 详细信息

关键词： pattern connectivity functional

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A Hybrid Level Set Optimization Design Method of Functionally Graded Cellular Structures Considering connectivity

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Computers, Materials & Continua 2024年第4期79卷 1-18页

作者： Yan Dong Kang Zhao Liang Gao Hao Li The State Key Lab of Digital Manufacturing Equipment and Technology Huazhong University of Science and TechnologyWuhan430074China Institute of Systems Engineering China Academy of Engineering PhysicsMianyang621900China

With the continuous advancement in topology optimization and additive manufacturing(AM)technology,the capability to fabricate functionally graded materials and intricate cellular structures with spatially varying microstructures has grown significantly.However,a critical challenge is encountered in the design of these structures–the absence of robust interface connections between adjacent microstructures,potentially resulting in diminished efficiency or macroscopic failure.A Hybrid Level Set Method(HLSM)is proposed,specifically designed to enhance connectivity among non-uniform microstructures,contributing to the design of functionally graded cellular structures.The HLSM introduces a pioneering algorithm for effectively blending heterogeneous microstructure interfaces.Initially,an interpolation algorithm is presented to construct transition microstructures seamlessly connected on both sides.Subsequently,the algorithm enables the morphing of non-uniform unit cells to seamlessly adapt to interconnected adjacent microstructures.The method,seamlessly integrated into a multi-scale topology optimization framework using the level set method,exhibits its efficacy through numerical examples,showcasing its prowess in optimizing 2D and 3D functionally graded materials(FGM)and multi-scale topology optimization.In essence,the pressing issue of interface connections in complex structure design is not only addressed but also a robust methodology is introduced,substantiated by numerical evidence,advancing optimization capabilities in the realm of functionally graded materials and cellular structures.

关键词： Hybrid level set method functionally graded cellular structure connectivity interpolated transition optimization design

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Investigation of replacing tracer flooding analysis by capacitance resistance model to estimate interwell connectivity

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Petroleum 2023年第1期9卷 61-71页

作者： Adilet Aliyev Davood Zivar Peyman Pourafshary School of Mining and Geosciences Nazarbayev UniversityAstanaKazakhstan PanTerra Geoconsultants B.V LeiderdorpNetherlands

Interwell connectivity is an essential parameter for managing waterflooding operations in a field.Analysis of the tracer injection operation is a well-known approach to studying injected fluids distribution in a reservoir and toward producer wells.Developed in the early 2000s,capacitance-resistance model(CRM)is an analytical approach for waterflooding modeling and optimization.Production/injection data are used as input to model the mass balance and estimate parameters such as the interwell connectivity.In this work,we investigated the accuracy of applying the capacitance-resistance model to mimic a tracer test.Such an approach helps assess the connection between the wells and decide on further field development steps cheaper and quicker.connectivity values estimated by tracer tests and CRM were analyzed and compared for synthetic and real fields.CRM was capable of modeling waterflooding and estimating production in both fields with acceptable accuracy.Parameters such as well spacing and fluid loss during the injection were considered to improve the accuracy of the CRM approach to calculate the interwell connectivity between injector/producer pairs.Our study showed that CRM could serve as a tool for a quick approximate estimation of interwell connectivity under certain assumptions and is recommended as a replacement for tracer flooding analysis,where the tracer test is not possible or is expensive.

关键词： connectivity capacitance analysis

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Erratum to: Page numbers for articles in Journal of Mountain Science Volume 21 Issue 3

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Journal of Mountain Science 2024年第4期21卷 1444-1445页

作者： JMS editorial office 不详

The original online version of this issue has wrong page range(361-716).The correct page range for this issue should be 719-1074.The page number for every article in this issue has also been corrected as follows:719-733 https://***/10.1007/s11629-023-8333-x Article title:Floristic composition and edaphic relationships in ferruginous campo rupestre reference ecosystems 734-753 https://***/10.1007/s11629-023-8399-5 Article title:Assessment of sediment connectivity using modelling and field-based approaches in the SlavíčRiver catchment(MoravskoslezskéBeskydy Mts,Czech Republic).

关键词： connectivity ecosystems Republic

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Unveiling the brain’s symphony:exploring the necessity and sufficiency of neural networks in behavior control

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Neural Regeneration Research 2025年第1期20卷 186-187页

作者： Fernando Jose Bustos Instituto de Ciencias Biomedicas Facultad de Medicina y Facultad de Ciencias de la VidaUniversidad Andres BelloSantiagoChile Millennium Nucleus of Neuroepigenetics and Plasticity(EpiNeuro) SantiagoChile

Since the pioneering work by Broca and Wernicke in the 19th century,who examined individuals with brain lesions to associate them with specific behaviors,it was evident that behaviors are complex and cannot be fully attributable to specific brain areas alone.Instead,they involve connectivity among brain areas,whether close or distant.At that time,this approach was considered the optimal way to dissect brain circuitry and function.These pioneering efforts opened the field to explore the necessity or sufficiency of brain areas in controlling behavior and hence dissecting brain function.However,the connectivity of the brain and the mechanisms through which various brain regions regulate specific behaviors,either individually or collaboratively,remain largely elusive.Utilizing animal models,researchers have endeavored to unravel the necessity or sufficiency of specific brain areas in influencing behavior;however,no clear associations have been firmly established.

关键词： behavior connectivity neural

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Next generation drug connectivity mapping for acquiring therapeutic agents to differentially regulate myelination

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Neural Regeneration Research 2023年第4期18卷 797-798页

作者： Kasum Azim Andrea Domenico Rivera Arthur Morgan Butt Department of Neurology Medical FacultyHeinrich-Heine-UniversityDüsseldorfGermany Institute of Biomedical and Biomolecular Sciences School of Pharmacy and Biomedical ScienceUniversity of PortsmouthSt Michael’s BuildingWhite Swan RoadPortsmouthUK Section of Human Anatomy Department of NeuroscienceUniversity of PaduaPaduaItaly

The need for new therapeutic approaches:Conventional drug discovery is a lengthy and expensive process,taking decades and billions of dollars to get a drug from bench to bedside.Much of the costs incurred are at the pre-clinical stages,between drug design and synthesis to delineating the cellular“Mechanisms of Action”(MoA).Notably,there is a very high risk of failure,and only a very small proportion of therapeutic agents reach later-phase clinical trials.Accordingly,drug repositioning has become a valuable strategy aimed at fast-tracking treatments into clinical use and improving the chances of therapeutic success.A novel addition to this approach is connectivity mapping,which defines cell-specific transcriptional responses to small molecules in disease-dependent contexts.This commentary outlines how some of the latest innovations in connectivity mapping can be exploited for drug repurposing.

关键词： connectivity dollar therapeutic

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Improving Domain Repository connectivity

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Data Intelligence 2023年第1期5卷 6-26页

作者： Ted Habermann Metadata Game Changers

Domain repositories,i.***.repositories that store,manage,and persist data pertaining to a specific scientific domain,are common and growing in the research landscape.Many of these repositories develop close,long-term communities made up of individuals and organizations that collect,analyze,and publish results based on the data in the repositories.Connections between these datasets,papers,people,and organizations are an important part of the knowledge infrastructure surrounding the repository.All these research objects,people,and organizations can now be identified using various unique and persistent identifiers(PIDs)and it is possible for domain repositories to build on their existing communities to facilitate and accelerate the identifier adoption process.As community members contribute to multiple datasets and articles,identifiers for them,once found,can be used multiple times.We explore this idea by defining a connectivity metric and applying it to datasets collected and papers published by members of the UNAVCO community.Finding identifiers in DataCite and Crossref metadata and spreading those identifiers through the UNAVCO DataCite metadata can increase connectivity from less than 10%to close to 50%for people and organizations.

关键词： Persistent Identifier Domain Repository ORCID ROR connectivity PID Graph

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Regional differences in gully network connectivity based on graph theory:a case study on the Loess Plateau,China

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Journal of Mountain Science 2023年第4期20卷 1035-1050页

作者： CHENG Jian-hua LUO Lan-hua LI Fa-yuan LIU Lu-lu CUI Ling-zhou School of Geography Nanjing Normal UniversityNanjing210023China Key Laboratory of Virtual Geographic Environment Ministry of EducationNanjing Normal UniversityNanjing210023China Jiangsu Center for Collaborative Innovation in Geographical Information Resource Development and Application Nanjing Normal UniversityNanjing210023China School of Geography and Ocean Science Nanjing UniversityNanjing210023China College of Life and Environmental Science Wenzhou UniversityWenzhou325035China

Material exchange frequently occurs in gullies,and thus the relationship between a gullynetwork structure and sediment transport potential has attracted considerable interest.However,previous researches ignored the difficulty of material transport from sources to sinks,and did not quantify the connectivity of a network structure.In this study,we used a graph model structure to model gully networks of six typical sample areas in the Loess Plateau of China and quantified gully network connectivity using four indexes:average node strength,accessibility from sources to sinks,potential flow,and network structural connectivity index.Results show that:(1)Reflected by different quantitative indexes,the trends of gully network connectivity in different regions are similar.From north to south,the connectivity of a sample area first increases and then decreases.(2)The more mature gullies have stronger network connectivity.Small resistance is conducive to material transport in the gullies.(3)The node connectivity index of the gully network shows a significant aggregation distribution in space,and node connectivity on the main channel is often stronger than that on the branch trench.These results not only deepen the understanding of the process and mechanism of loess gully geomorphic development and evolution but also provide a reference for geomorphic studies.

关键词： Graph theory Gully network Loess Plateau connectivity Regional difference

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