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Status epilepticus as a complication after COVID-19 mRNA-1273 vaccine:A case report

World Journal of Clinical Cases 2021年第24期9卷 7218-7223页

作者： Robin Sin Denisa Struncova Department of Infectious Diseases and Travel Medicine Faculty of Medicine in PilsenCharles UniversityUniversity Hospital PilsenPilsen 30599Czech Republic Medical Department Emergency Medical Service of the Pilsen RegionPilsen 30100Czech Republic Department of Anaesthesiology and Intensive Care Medicine University Hospital PilsenPilsen 30460Czech Republic Faculty of Medicine Masaryk UniversityBrno 62500Czech Republic

BACKGROUND We present a rare case of status epilepticus in a 56-year-old man which arose as a complication after vaccination with the coronavirus disease 2019(COVID-19)mRNA-1273 *** patient's history included well-compensated secondary *** root cause of the situation was a fever which had developed as a side effect of the *** SUMMARY A 56-year-old man received the first dose of mRNA-1273 vaccine against the severe acute respiratory *** vaccine was administered intramuscularly(100 mg,0.5 mL).The next morning the man was found to be suffering from fever and headaches while at the same time experiencing general *** lost consciousness suddenly and experienced generalized clonic seizures which turned into status *** the Emergency Medical Service arrived the patient was unconscious with spontaneous breathing and generalized clonic *** was necessary to administer diazepam *** was also necessary to administer high doses of levetiracetam and temporary *** status epilepticus was brought under control approximately 90 min after the patient’s transport to the Emergency Department.A follow-up electroencephalogram no longer revealed abnormal indications of epileptic *** patient was temporarily hospitalized in the Intensive Care Unit and after seven days care was discharged without any further apparent *** There is currently no specific treatment against ***,the benefits of COVID-19 vaccine protection outweigh the risks.

关键词： SARS-CoV-2 COVID-19 mRNA vaccine complication of vaccination Status epilepticus Case report

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