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Kaempferia parviflora ethanol extract improves self-assessed sexual health in men:a pilot study

Journal of Integrative Medicine 2018年第4期16卷 249-254页

作者： Richard A.Stein Kira Schmid Jowell Bolivar Andrew G.Swick Steven V.Joyal Steven P.Hirsh Life Extension 3600 West Commercial BlvdFort tauderdaleFL 33309USA Life Extension Clinical Research Inc.5990 North Federal HighwayFort LauderdaleFL 33308USA

Background： Sexual health positively correlates with overall wellbeing. Existing therapeutics to enhance male sexual health are limited by factors that include responsiveness, adherence and adverse effects. As the population ages, safe and effective interventions that preserve male sexual function are needed. Published research suggests that various preparations of Kaempferia parviflora, a plant in the Zingiberaceae （ginger） family, support cardiovascular health and may ameliorate erectile function. Objective： The aim of this study was to examine the effects of kaempmaxtm, an ethanol extract of the K. parvi]lora rhizome, on erectile function in healthy middle-aged and older men. Design, setting, participants and interventions： We conducted an open-label, one-arm study on 14 generally healthy males aged 50-68 years with self-reported mild erectile dysfunction, who were not using pre- scription treatments. Participants took 100 mg kaempmaxtm daily for 30 days. Main outcome measures： Evaluations were conducted at baseline and on the final study assessment. Primary efficacy analyses included the International Index of Erectile Function （IIEF）; secondary efficacy analyses included the global Assessment Question about erectile function. Results： Thirteen participants completed the 30-day study. Supplementation with kaempmaxtm resulted in statistically significant improvements in erectile function, intercourse satisfaction and total scores on the IIEF questionnaire. kaempmaxtm was well tolerated and exhibited an excellent safety profile. Conclusion： Our results suggest that kaempmaxtm may improve erectile function in healthy middle-aged and older men. While the effects were not as pronounced as what might be seen with prescription med- ication, most participants found them satisfactory. Additional, longer and placebo-controlled clinical tri- als will be needed. Trial registration： *** identifier Ncr03389867.

关键词： Sexual health Kaempferia parviflom complementary therapies kaempmax^tm global Assessment QuestionInternational Index of Erectile Function

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