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Assessment of compliance to sulfadoxine-pyrimethamine 18 months after phasing out chloroquine in Mkuranga District,Coast region-Tanzania

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Asian Pacific Journal of Tropical Medicine 2010年第6期3卷 451-453页

作者： Stephen ED Nsimba Phare G Mujinja Prospective College of Health & Allied Sciences(CHAS) School Of MedicineP.O.Box 395DodomaTanzania-East Africa Muhimbili University of Health and Allied Sciences School of Public Health & Social SciencesP.O.Box 65015Dar-es-Salaam Tanzania

Objective:To observe and assess the compliance to sulfadoxine-pyrimethamine(SP) one and a half years after phasing out chloroquine(CQ) in Mkuranga District,Coast region,Tanzania. Methods:A randomly controlled baseline community study was conducted in rural areas of Mkuranga district,***-structured questionnaire consisted of open-and closed -ended questions including home stocking,home use,last fever episodes and treatment of underfives with malaria using CQ or ***:The prevalence of fever or reported fever rate during the last 48 hours by their mothers or guardians was high(70%).Of all 117 blood samples,only 8 children after drug analysis were found to have CQ and 13 had SP concentrations within their blood *** of these blood drug levels were above therapeutic ranges. Conclusions:Community interventions are urgently needed in rural communities and should specifically target households nucleus on early malaria fever recognition and provision of recommended antimalarials for the sick underfive ***,sadly,there was an increase in underweight and undernourishment in the study areas,probably because of malaria in the area and poverty which are associated with poor nutrition in these youngsters.

关键词： Malaria Sulfadoxine-pyrimethamine complaince Choroquine

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