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comparative evaluation of a rapid diagnostic test,an antibody ELISA,and a pLDH ELISA in detecting asymptomatic malaria parasitaemia in blood donors in Buea,Cameroon

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Infectious Diseases of Poverty 2017年第1期6卷 931-939页

作者： Tebit Emmanuel Kwenti Longdoh Anna Njunda Beltine Tsamul Shey Dickson Nsagha Nguedia Jules-Clement Assob Kukwah Anthony Tufon Dilonga Henry Meriki Enow George Orock Department of Medical Laboratory Sciences Faculty of Health SciencesUniversity of BueaP.B.63BueaSouthwest RegionCameroon Department of Public Health and Hygiene Faculty of Health SciencesUniversity of BueaP.B.63BueaSouthwest RegionCameroon Blood Bank Regional Hospital BueaP.B.32BueaSouthwest RegionCameroon Programme in Medicine Faculty of Health SciencesUniversity of BueaBueaSouthwest RegionCameroon

Background:In malaria endemic areas,infected blood donors serve as a source of infection to blood recipients,which may adversely affect their *** necessitates the proper screening of blood to be used for transfusion in these *** purpose of this study was to determine the prevalence of malaria parasitaemia in blood donors in Buea,Cameroon,and to evaluate the performance of a rapid diagnostic test(RDT),a malaria antibody enzyme-linked immunosorbent assay(ELISA),and a Plasmodium lactate dehydrogenase(pLDH)ELISA in the detection of asymptomatic malaria parasitaemia in the target ***:In a prospective study conducted between September 2015 and June 2016,1240 potential blood donors were *** donors were screened for malaria parasites using Giemsa microscopy(GM)and a RDT.A sub-sample of 184 samples,comprising 88 positive and 96 negative samples,were selected for the evaluation of the pLDH ELISA and the antibody *** chi-square test and correlation analysis were performed as part of the statistical *** statistical significance cut-off was set at P<***:The prevalence of malaria parasitaemia in this study was found to be 8.1%(95%CI:6.6-9.7).The prevalence was not observed to be dependent on the age or sex of the *** RDT had a sensitivity(88.0%),specificity(99.1%),and negative predictive value(99.0%)higher than the *** performance of the pLDH ELISA,which demonstrated the highest positive predictive value(91.6%),was generally comparable to the *** sensitivity was lowest with the antibody ELISA(69.9%),which also demonstrated the highest false positive and false negative *** detection threshold for the pLDH(three parasites/μl)was lower compared to the RDT(50-60 parasites/μl).Non-significant positive correlations were observed between the parasite density and the pLDH titers and malaria antibody ***:Overall,the RDT and the pLDH ELISA demonstrated a perfectly correlated agreem

关键词： Blood transfusion Malaria RDT pLDH ELISA Malaria antibody ELISA comparative evaluation Sensitivity Specificity Buea Cameroon

comparative evaluation and Comprehensive Analysis of Machine Learning Models for Regression Problems

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Data Intelligence 2022年第3期4卷 620-652页

作者： Boran Sekeroglu Yoney Kirsal Ever Kamil Dimililer Fadi Al-Turjman Information Systems Engineering Department Near East UniversityNicosiaCyprusMersin 10Turkey Software Engineering Department Near East UniversityNicosiaCyprusMersin 10Turkey Electrical and Electronic Engineering Department Near East UniversityNicosiaCyprusMersin 10Turkey Artificial Intelligence Engineering Department Near East UniversityNicosiaCyprusMersin 10Turkey Research Centre for AI and IoT Near East UniversityNicosiaCyprusMersin 10Turkey

Artificial intelligence and machine learning applications are of significant importance almost in every field of human life to solve problems or support human experts. However, the determination of the machine learning model to achieve a superior result for a particular problem within the wide real-life application areas is still a challenging task for researchers. The success of a model could be affected by several factors such as dataset characteristics, training strategy and model responses. Therefore, a comprehensive analysis is required to determine model ability and the efficiency of the considered strategies. This study implemented ten benchmark machine learning models on seventeen varied datasets. Experiments are performed using four different training strategies 60:40, 70:30, and 80:20 hold-out and five-fold cross-validation techniques. We used three evaluation metrics to evaluate the experimental results: mean squared error, mean absolute error, and coefficient of determination(R2score). The considered models are analyzed, and each model’s advantages, disadvantages, and data dependencies are indicated. As a result of performed excess number of experiments, the deep Long-Short Term Memory(LSTM) neural network outperformed other considered models, namely, decision tree, linear regression, support vector regression with a linear and radial basis function kernels, random forest, gradient boosting, extreme gradient boosting, shallow neural network, and deep neural network. It has also been shown that cross-validation has a tremendous impact on the results of the experiments and should be considered for the model evaluation in regression studies where data mining or selection is not performed.

关键词： Machine learning Regression comparative evaluation Analysis Validation

comparative evaluation of Geological Heritage Landscapes in Dali-Cangshan Global Geopark

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Chinese Journal of Urban and Environmental Studies 2022年第3期10卷 124-145页

作者： LI Zhang DUAN Xiaodi Tianjin University West Yunnan University of Applied Sciences Dali Vocational and Technical College of Agriculture and Forestry

Cangshan Glacier is one of the southernmost mountains in the Northern Hemisphere(Asian Continent) during the last Quaternary glaciation, and is a standard area with well-preserved and abundant traces of Quaternary Dali glaciation. In this study, the geological heritage resources of Cangshan Mountain are evaluated in terms of condition indicator and value indicator. Through the determination of quantitative evaluation indicators and evaluation factor weights of geological heritage landscapes, the geological heritage resources of Cangshan Mountain are identified and classified. The results show that there are two world-class geological heritage landscapes,14 national geological heritage landscapes, 54 provincial geological heritage landscapes and55 geological relic landscapes below the provincial level in the park. Cangshan Mountain’s geological heritage resources are compared with glacial heritage resources, Quaternary glaciation resources and tectonic geomorphic heritage resources both at home and abroad, so as to form a complete evaluation of the geological heritage landscape resources of Cangshan Mountain.

关键词： Geological heritage landscapes evaluation indicator and factor geological heritage resources comparative evaluation classification and comparison

comparative evaluations of the Monte Carlo-based light propagation simulation packages for optical imaging

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Journal of Innovative Optical Health Sciences 2018年第1期11卷 80-89页

作者： Lin Wang Shenghan Ren Xueli Chen School of Information Sciences and Technology Northwest University Xi'an Shaanxi 710127P.R.China Engineering Research Center of Molecular and Neuro Imaging of Ministry of Education School of Life Science and Technology Xidian University Xi'an Shaanxi 710126P.R.China

Monte Carlo simulation of light propagation in turbid medium has been studied for years.A number of software packages have been developed to handle with such ***,it is hard to compare these simulation packages,especially for tissues with complex heterogeneous ***,we first designed a group of mesh datasets generated by Iso2Mesh software,and used them to cross-validate the accuracy and to evaluate the performance of four Monte Carlo-based simulation packages,including Monte Carlo model of steady-state light transport in multi-layered tissues(MCML),tetrahedron-based inhomogeneous Monte Carlo optical simulator(TIMOS),Molecular Optical Simulation Environment(MOSE),and Mesh-based Monte Carlo(MMC).The performance of each package was evaluated based on the designed mesh *** merits and demerits of each package were also *** results showed that the TIMOS package provided the best performance,which proved to be a reliable,efficient,and stable MC simulation package for users.

关键词： Light transport Monte Carlo comparative evaluation mesh datasets.

Multislice spiral computed tomography imaging in evaluating hemophilic arthropathy

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Chinese Medical Journal 2020年第14期133卷 1669-1675页

作者： Yu-Xia Zhang M ei-Xia Li Shu-Fang Wei Lu Zhang Tian-Ming Cheng Ying-Hui Ge Department of Medical Imaging People's Hospital of Zhengzhou UniversityHenan Provincial People's HospitalCentral China Fuwai HospitalZhengzhouHenan 450003China Department of Radiology The First Affiliated Hospital of Xinxiang Medical UniversityWeihuiHenan 453100China Department of Medical Imaging People's Hospital of Zhengzhou UniversityHenan Provincial People's HospitalZhengzhouHenan 450003China

Background:Certain hemophilia patients are unable to cooperate with or afford magnetic resonance imaging(MRI)*** purpose of our study was to explore the value of multislice spiral computed tomography(MSCT)in evaluating hemophilic arthropathy(HA).Methods:Thirty-eight patients with 73 joints of HA were consecutively selected from January 2016 to May 2018 for this prospective *** 73 joints were examined by X-ray,CT,and MRI within 2 *** MRI scores of the joints were determined by the International Prophylaxis Study Group(IPSG)*** CT findings were quantified according to the IPSG standard,except for cartilage injury,which was quantified by joint space narrowing using the X-ray Pettersson *** CT and MRI scores were compared by the paired Wilcoxon signed-rank *** correlations between the CT score of joint space narrowing and MRI score of cartilage injury and the total CT and MRI scores were analyzed by Spearman rank *** kappa test was used to compare the consistency of CT and MRI ***:MRI was superior to CT based on the scores for small amount of effusion(P0.05),and there was a high degree of consistency between the two scores(kappa>0.81).The consistency between the Pettersson scores of joint space narrowing on CT and the IPSG scores of cartilage injury on MRI was high(kappa=0.774,Pevaluation of HA.

关键词： Hemophilia Arthritis Magnetic resonance imaging Computed tomography Radiography comparative evaluation

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