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combined detection tumor markers for diagnosis and prognosis of gallbladder cancer

World Journal of Gastroenterology 2014年第14期20卷 4085-4092页

作者： Yun-Feng Wang Fei-Ling Feng Xu-Hong Zhao Zhen-Xiong Ye He-Ping Zeng Zhen Li Xiao-Qing Jiang Zhi-Hai Peng Department of Hepatobiliary Surgery Qianfoshan HospitalShandong University Department of General Surgery Yangpu HospitalTongji University School of Medicine The First Department of Biliary Surgery Eastern Hepatobiliary Surgery Hospital of the Second Military Medical University Central Experiment Laboratory Yangpu HospitalTongji University School of Medicine

AIM: To clarify the value of combined use of markers for the diagnosis of gallbladder cancer and prediction of its prognosis. METHODS: Serum cancer antigens (CA) 199, CA242, carcinoembryonic antigen (CEA), and CA125 levels were measured in 78 patients with gallbladder cancer (GBC), 78 patients with benign gallbladder diseases, and 78 healthy controls using electrochemiluminescence. CA199, CA242, CEA, and CA125 levels and positive rates were analyzed and evaluated pre-and post-operatively. Receiver operator characteristic curves were used to determine diagnostic sensitivity and specificity of GBC. Survival time analysis, including survival curves, and multivariate survival analysis of a Cox proportional hazards model was performed to evaluate independent prognostic factors. RESULTS: Serum CA242, CA125, and CA199 levels in the GBC group were significantly higher when compared with those in the benign gallbladder disease and healthy control groups (P < 0.01). With a single tumor marker for GBC diagnosis, the sensitivity of CA199 was the highest (71.7%), with the highest specificity being in CA242 (98.7%). Diagnostic accuracy was highest with a combination of CA199, CA242, and CA125 (69.2%). CA242 could be regarded as a tumor marker of GBC infiltration in the early stage. The sensitivity of CA199 and CA242 increased with progression of GBC and advanced lymph node metastasis (P < 0.05). The 78 GBC patients were followed up for 6-12 mo (mean: 8 mo), during which time serum CA199, CA125, and CA242 levels in the recurrence group were significantly higher than in patients without recurrence (P < 0.01). The post-operative serum CA199, CA125, and CA242 levels in the non- recurrence group were significantly lower than those in the GBC group (P < 0.01). Multivariate survival analysis using a Cox proportional hazards model showed that cancer of the gallbladder neck and CA199 expression level were independent prognostic factors. CONCLUSION: CA242 is a marker of GBC infiltration in

关键词： Gallbladder cancer Tumor marker combined detection Diagnosis Prognosis

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Beam pointing correction of variable polarization MMW/IR combined detection

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Journal of Beijing Institute of Technology 2012年第1期21卷 96-100页

作者：刘建勋张伟邓洪孙厚军吕昕 School of Information and Electronics Beijing Institute of Technology Xi'an Modern Control Technologies Research Institute

A kind of beam-scanning algorithm of variable polarization millimeter array antenna based on the phased array technology is put forward in this paper. The algorithm can be successfully applied to deal with beam directivities inconsistency of millimeter wave/infrared（ MMW/IR ） multimode detector, it can keep electric axis and optical axis coincident. Accordingly, this method can decrease the data fusion difficulty and improve the accuracy of angle measurement. Simulation results show that variable polarization millimeter array antenna has flexible beam-scanning abibility within ±0.5° after the algorithm was adopted, simultaneously, antenna polarization purity is better than 20 dB within the half power beamwidth, sidelobe imbalance keeps high available and antenna gain of the sum beam is over 26.8 dB.

关键词： phased array digital beamforming variable polarization combined detection

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A Fast Acquisition Algorithm For L1C Based On L1CA And L1C combined detection

A Fast Acquisition Algorithm For L1C Based On L1CA And L1C C...

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第三届中国卫星导航学术年会

作者： Yuan Huadong, Lv Jing, Yu Yong, Chang Jiang Institute of Communication Engineering, PLA University of Science and Technology, Nanjing, China

Focusing on the two problems of multiple peaks and overlong time which the receiver has to face in the acquisition process of L1C , a fast acquisition algorithm based on L1CA and L1C combined detection is presented in this paper. This new algorithm is implemented to remove multiple peaks by accumulating the autocorrelation peaks of the two signals coherently. In order to reduce the search realm of the code phase, a method "Pre-detection + Sub-search" was introduced in this new algorithm. The simulation results show that the proposed algorithm can not only reduce the search realm of the code phase significantly but also improve the acquisition sensitivity to some extend.

关键词： L1C combined detection multiple peaks removal Pre-detection Sub-search

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Analysis and Interpretation of detection Results of Novel Coronavirus Nucleic Acids and Specific Antibodies

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Chinese Journal of Biomedical Engineering(English Edition) 2020年第1期29卷 34-38页

作者： Dongliang Li Jia Ye Yunhua Yu Guoqing Yu Chuanshen Jiang Xianliang Lin Wenfeng Lin Youguang Lu The 900th Hospital of the Joint Logistics Support Force of Chinese PLA Fuzhou 350000 China

The novel coronavirus(2019 novel coronavirus,2019-nCoV) is a newly emerged ***,the nucleic acid detection technology and serum immunological detection technology established urgently in emergencies have certain defects *** efficiency of nucleic acid and antibody detection varies at different stages of disease progression of the novel coronavirus disease(COVID-19).If the two can be used in combination and the results of the analysis can be comprehensively judged,they can be combined to monitor the viral load and disease progress better and improve the diagnostic *** on the author’s application experience,this article analyzes and interprets eight common modes of combined detection of nucleic acids and specific antibodies in order to provide a reference for the clinical diagnosis and treatment of COVID-19.

关键词： novel coronavirus COVID-19 nucleic acid specific antibody combined detection

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日本血吸虫病与HBV感染的关系

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寄生虫病与感染性疾病 1995年第4期 147-147页

作者：张桂盛周国兴叶治碧黄启华吴子松四川省寄生虫病防治研究所

日本血吸虫病与ＨＢＶ感染的关系四川省寄生虫病防治研究所成都６１００４１张桂盛，周国兴，叶治碧，黄启华，吴子松为了解四川地区日本血吸虫病与ＨＢＶ感染之间的关系，我们对血吸虫病流行与非流行地区部分人群进行了血吸虫病和ＨＢ... 详细信息

日本血吸虫病与ＨＢＶ感染的关系四川省寄生虫病防治研究所成都６１００４１张桂盛，周国兴，叶治碧，黄启华，吴子松为了解四川地区日本血吸虫病与ＨＢＶ感染之间的关系，我们对血吸虫病流行与非流行地区部分人群进行了血吸虫病和ＨＢＶ感染的调查，并将结果进行了比较，...

关键词： Schistosomiasis circulating antigen circulating antibody combined detection

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