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CEREBRAL BLOOD FLOW AND METABOLISM EVALUATION IN comatose PATIENTS BY DYNAMIC SPECT

Nuclear Science and Techniques 1993年第1期4卷 33-38页

作者： AlessandroGiordano MariaLuciaCalcagni FrancescoDellaCorte MarianoAlbertoPennisi Guido Galli 王凤琴赵惠杨 Institute of Nuclear Medicine Institute of Anaesthesiology and Intensive Care of the Catholic University of the Sacred Heart Roma Italy Zhongshan Hospital Shanghai Medical University Shanghai 200032 China

Thirty patients in coma state underwent dynamic SPECT with 133Xe, a validated technique for the quantitation of CBF by SPECT, using a new brain dedicated tomograph: CERTO-96. CMRO2 was computed by multiplying the mean CBF by AVDO2 according to the Fick’s principle. The mean values of CBF, AVDO2 and CMRO2 in patients with good outcome were significantly different from those with worse outcome. On the basis of the best "discriminant threshold", CBF and AVDO2 demonstrated an intermediate accuracy in separating the two groups, while CMRO2 showed a satisfactory accuracy.

关键词： Dynamic SPECT Cerebral blood flow Cerebral metabolic rate of oxygen comatose patients

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The EEG Analysis of Auditory Emotional Stimuli Perception in TBI Patients with Different SCG Score

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Open Journal of Modern Neurosurgery 2014年第2期4卷 81-96页

作者： Portnova Galina Kseniia Gladun Ivanitskii Alexey Institute of Higher Nervous Activity and Neurophysiology of Russian Academy of Science (IHNA) Moscow Russia

The electroencephalographic research has focused on the variety of responses to emotional auditory stimulation in patients at different stages after craniocerebral trauma. The patients sampling consisted of three groups: 13 comatose patients, 14 severe TBI patients, 12 moderate TBI patients, the control group consisting of the 28 healthy adults. The subjects were stimulated with auditory stimuli containing significant sounds (coughing, laughing, crying, bird singing, barking, scraping) and control sounds (white noise). We have analyzed statistically significant differences of power of the rhythmic activity registered during the presentation of different types of stimuli using Matlab. The t-test differences for each type of stimuli and the background were calculated as well as major ANOVA-effects. The results showed that EEG-response was based on the emotional stimuli valence, the consciousness levels, the severity of injury and the recovery process. The TBI patients showed lower theta-rhythm power in the frontal areas in response to the all emotional stimuli. The alpha-activity was reduced in the TBI patients: the alpha-rhythm depression was most vividly pronounced in the control group. The alpha-rhythm acceleration in the occipital areas was found only in the moderate TBI patients and only to the emotional stimuli. The severe TBI and comatose patients showed lower response rates to the neutral stimuli and higher response rates to the unpleasant physiological stimuli.

关键词： comatose Patients TBI EEG Rhythmic Power Recovery

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