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BRIEF ARTICLE New reduced volume preparation regimen in colon capsule endoscopy

World Journal of Gastroenterology 2012年第17期18卷 2092-2098页

作者： Yasuo Kakugawa Yutaka Saito Shoichi Saito Kenji Watanabe Naoki Ohmiya Mitsuyuki Murano Shiro Oka Tetsuo Arakawa Hidemi Goto Kazuhide Higuchi Shinji Tanaka Hideki Ishikawa Hisao Tajiri Division of Screening Technology and Development Research Center for Cancer Prevention and ScreeningNational Cancer CenterTokyo 104-0045Japan endoscopy Division National Cancer Center HospitalTokyo 104-0045Japan Department of endoscopy Jikei University School of MedicineTokyo 105-8461Japan Department of Gastroenterology Osaka City University Graduate School of MedicineOsaka 545-8685Japan Department of Therapeutic Medicine Nagoya University Graduate School of MedicineNagoya 466-8560Japan Second Department of Internal Medicine Osaka Medical CollegeOsaka 569-8686Japan Department of endoscopy Hiroshima University HospitalHiroshima 734-8551Japan Department of Molecular-Targeting Cancer Prevention Graduate School of Medical ScienceKyoto Prefectural University of MedicineKyoto 602-0841Japan

AIM:To evaluate the effectiveness of our proposed bowel preparation method for colon capsule ***:A pilot,multicenter,randomized controlled trial compared our proposed "reduced volume method"(group A) with the "conventional volume method"(group B) preparation *** A did not drink polyethylene glycol electrolyte lavage solution(PEGELS) the day before the capsule procedure,while group B drank 2 *** the procedure day,groups A and B drank 2 L and 1 L of PEG-ELS,respectively,and swallowed the colon capsule(PillCam colon capsule).Two hours later the first booster of 100 g magnesium citrate mixed with 900 mL water was administered to both groups,and the second booster was administered six hours post capsule ingestion as long as the capsule had not been excreted by that *** videos were reviewed for grading of cleansing level,RESULTS:Sixty-four subjects were enrolled,with results from 60 *** A and B included 31 and 29 subjects,***-nine(94%) subjects in group A and 25(86%) subjects in group B had adequate bowel preparation(ns).Twenty-two(71%) of the 31 subjects in group A excreted the capsule within its battery life compared to 16(55%) of the 29 subjects in group B(ns).Of the remaining 22 subjects whose capsules were not excreted within the battery life,all of the capsules reached the left side colon before they stopped functioning.A single adverse event was reported in one subject who had mild symptoms of nausea and vomiting one hour after starting to drink PEG-ELS,due to ingesting the PEG-ELS faster than ***:Our proposed reduced volume bowel preparation method for colon capsule without PEG-ELS during the days before the procedure was as effective as the conventional volume method.

关键词： colon capsule endoscopy polyethylene glycol electrolyte lavage solution colon cleanliness reduced volume preparation method isotonic magnesium citrate

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