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Artificial intelligence empowers the second-observer strategy for colonoscopy:a randomized clinical trial

Gastroenterology Report 2023年第1期11卷 216-223页

作者： Pu Wang Xiao-Gang Liu Min Kang Xue Peng Mei-Ling Shu Guan-Yu Zhou Pei-Xi Liu Fei Xiong Ming-Ming Deng Hong-Fen Xia Jian-Jun Li Xiao-Qi Long Yan Song Liang-Ping Li Department of Gastroenterology Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuanP.R.China Department of Gastroenterology The Affiliated Hospital of Southwest Medical UniversityLuzhouSichuanP.R.China Department of Gastroenterology Xinqiao HospitalThird Military Medical UniversityChongqingP.R.China Department of Gastroenterology Suining Central HospitalSuiningSichuanP.R.China

Background:In colonoscopy screening for colorectal cancer,human vision limitationsmay lead to highermiss rate of lesions;artificial intelligence(AI)assistance has been demonstrated to improve polyp ***,there still lacks direct evidence to demonstrate whether AI is superior to trainees or experienced nurses as a second observer to increase adenoma detection during *** this study,we aimed to compare the effectiveness of assistance fromAI and human observer during ***:A prospective multicenter randomized study was conducted from 2 September 2019 to 29 May 2020 at four endoscopy centers in *** patients were randomized to either computer-aided detection(CADe)-assisted group or observer-assisted *** primary outcome was adenoma per colonoscopy(APC).Secondary outcomes included polyp per colonoscopy(PPC),adenoma detection rate(ADR),and polyp detection rate(PDR).We compared continuous variables and categorical variables by using R studio(version 3.4.4).Results:A total of 1,261(636 in the CADe-assisted group and 625 in the observer-assisted group)eligible patients were ***(0.42 vs 0.35,P=0.034),PPC(1.13 vs 0.81,Pcolonoscopy and reduce disturbance to routine practice(*** No.:ChiCTR1900025235).

关键词： artificial intelligence colon cancer screening adenoma early detection computer-aided detection

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Stool DNA-based versus colonoscopy-based colorectal cancer screening: Patient perceptions and preferences

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Family Medicine and Community Health 2015年第3期3卷 2-8页

作者： Matthew V.Abola Todd F.Fennimore Marcia M.Chen Zhengyi Chen Ashutosh K.Sheth Gregory Cooper Li Li Department of Family Medicine and Community Health Case Western Reserve University School of Medicine11001 Cedar AvenueSuite 200ClevelandOH 44106USA Division of Gastroenterology University Hospitals Case Medical Center11100 Euclid AvenueClevelandOH 44106USA Case Comprehensive cancer Center Case Western Reserve University School of Medicine10900 Euclid AvenueClevelandOH 44106USA Swetland Center for Environmental Health Case Western Reserve University11000 Cedar AvenueSuite 402ClevelandOH 44106USA

Objective:Stool DNA(sDNA)tests offer a noninvasive form of colon cancer screening for pa-tients,and although the test is expected to increase uptake of colon cancer screening,it is unknown if patients’perceptions of the sDNA test differ according to race and other patient ***:We conducted a self-administered survey of patients undergoing both a colonoscopy and an sDNA test to evaluate perceptions of sDNA ***:Of the 613 participants who were sent surveys,423 responded(69%response rate).Respondents self-identified as African American(n=127,30%),Caucasian(n=284,67%),and other ethnicity(n=12,3%).In general,participants found the sDNA test more suitable than a colonos-copy(n=309,75%).In univariate analyses,a higher percentage of Caucasians as compared with African Americans found the sDNA test more suitable than a colonoscopy(89%vs.76%,pcancer remains a significant factor for patient’s preferences for screening regardless of ***:Our study shows no racial differences in the perception of and preference for sDNA testing for colon *** to increase the uptake of sDNA testing may help reduce racial disparities in colorectal cancer.

关键词： colon cancer screening race stool DNA test patient perceptions

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