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Exercise Catheterization for Hemodynamic Evaluation of Adults with coarctation of the aorta

Congenital Heart Disease 2022年第6期17卷 605-615页

作者： Irene Martin de Miguel C.Charles Jain Alexander C.Egbe Jason H.Anderson Heidi M.Connolly William R.Miranda Department of Cardiovascular Medicine Mayo ClinicRochesterMinnesotaUSA Department of Pediatric and Adolescent Medicine Division of Pediatric CardiologyMayo ClinicRochesterMinnesotaUSA

Background: coarctation of the aorta (CoA) is associated with a generalized arteriopathy and long-term complicationsdespite repair. Data on invasive exercise hemodynamics in this population are lacking. Accordingly, wereviewed adults with CoA undergoing exercise catheterization to assess 1. hemodynamic profile;2. feasibilityfor assessment of CoA severity. Methods: Twenty patients undergoing exercise cardiac catheterization (12 armadduction and 8 supine cycle ergometry) at a quaternary care center between 2004 and 2021 were identified. Restingand exercise hemodynamic data were abstracted from the procedure logs. Results: Mean age was 43.6 ±12.0 years. Eleven patients (55%) had resting pulmonary arterial wedge pressure (PAWP) >15 mmHg;amongthose undergoing arterial catheterization, left ventricular end-diastolic pressure was >15 mmHg in 63%. Elevenpatients (55%) had pulmonary hypertension: 7 (35%) combined and 4 (20%) isolated post-capillary. At peak exercise,ΔPAWP/Δcardiac output (CO) ≥2 and Δmean pulmonary artery pressure/ΔCO ≥3 mmHg/l/min were foundin 7 (78%) and 6 (67%) patients, respectively;the composite of exercise PAWP ≥25 mmHg or ΔPAWP/ΔCO>2 was seen in 12 (86%). CoA peak-to-peak gradients at baseline (n = 14) and during exercise (n = 9) were 12(3–16) and 16 mmHg (9–28), respectively. Only 2 patients had an increase in CoA gradient to >20 mmHg withexercise. Conclusions: Diastolic dysfunction and pulmonary hypertension were highly prevalent, with exerciseunmasking abnormal diastolic and pulmonary vascular reserve in some individuals. Most patients failed to showsignificant increases in CoA peak-to-peak gradients with exercise. Further studies are warranted to establish thebest diagnostic method for CoA severity assessment.

关键词： coarctation of the aorta exercise heart catheterization diastolic dysfunction hypertension

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NuMED CHEATHAM-PLATINUM STENT AND BALLOON IN BALLOON DELIVERY CATHETER FOR TREATMENT OF NATIVE coarctation of the aorta

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Chinese Medical Sciences Journal 2006年第1期21卷 65-67页

作者： Guang-yi Wang Bo Yang Zhi-feng Wang Jun Guo Lu-yue Gai Guang Zhi Department of Cardiology General Hospital of People＇s Liberation Army Beijing 100853

coarctation of the aorta (CoA) is a congenital heart defect involving a narrowing of the *** narrowed segment called coarctation is most likely to happen in the segment just after the aortic *** narrowing can be removed by surgery or sometimes by a nonsurgical balloon ***, aortic coarctation may recur even after successful surgery or balloon ***, coarctation can now be treated with nonsurgical balloon dilation associated with implanting a stent using cardiac *** we reported our experience in a 19-year-old boy with CoA who underwent successful covered Cheatham-Platinum (CP) stent implantation for the coarctation.

关键词： covered stent coarctation of the aorta catheter intervention

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Assessing coarctation of the aorta With Fetal Heart Quantification Technology

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Maternal-Fetal Medicine 2024年第3期6卷 147-155页

作者： Jiaojiao Yang Fang Tan Yuqin Shen Yuan Zhao Yan Xia Sihan Fan Xueqin Ji Department of Obstetrics and Gynecology Center General Hospital of Ningxia Medical UniversityYinchuanNingxia 750003China Ultrasound Medicine Department Xian Yang Central HospitalXianyangShaanxi 712099China Ultrasound Medicine Department Peking University First Hospital Ningxia Women’s and Children's Hospital(Ningxia Hui Autonomous Region Maternal and Child Health Hospital)YinchuanNingxia 750002China Ningxia Medical University YinchuanNingxia 750004China

Objective:To use fetal heart quantification(fetal HQ)technology to compare the coarctation of the aorta(CoA)and normal fetal heart structure and systolic function and to assess whether there are abnormalities in the fetal heart structure and systolic function associated with ***:This prospective cohort study was conducted from May 2020 to December 2022 and involved 18–40-week-old singleton pregnancies and 30 fetuses diagnosed with CoA using fetal echocardiography at the General Hospital of Ningxia Medical University and Peking University First Hospital Ningxia Women’s andChildren’s Hospital,*** control group contained 60 normal *** following parameters were recorded and analyzed statistically:four-chamber view(4CV)end-diastolic long diameter,4CV epicardial–contralateral epicardial transverse maximum diameter,4CV global sphericity index(GSI),left ventricular(LV)and right ventricular(RV)24-segment end-diastolic diameter(EDD),24-segment sphericity index(SI),LV-fractional area change(LV-FAC),LV-longitudinal strain(LV-LS),RV-fractional area change(RV-FAC),RV-longitudinal strain(RV-LS),and LV and RV 24-segment transverse fractional shortening(FS).Measurement data were compared between the two groups using an independent sample t test,with P0.9,indicating high consistency,and a coefficient of variable of<1%,indicating low *** analysis revealed no obvious correlation between gestational age and GSI,LV-FAC,LV-LS,RV-FAC,and RV-LS.A comparison of the fourchamber morphological structural parameters of the hearts in the two groups revealed that when compared with the control group,the 4CV end-diastolic long diameter was shortened in

关键词： Fetal heart Quantitative analysis technology Fetal HQ software coarctation of the aorta Spherical index Systolic function

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coarctation of aorta with complete aortic occlusion

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Journal of Geriatric Cardiology 2013年第4期10卷 383-385页

作者： Marc-Alexander Ohlow Bernward Lauer Department of Cardiology Zentralklinik Bad Berka Robert-Koch-Allee 999437 Bad Berka Germany

Survival to advanced age is exceptional in patients with unrepaired aortic coarctation. We report the case of an 81-year-old man with aortic coarctation and total occlusion who was otherwise asymptomatic. coarctation was suspected when a femoral-radial pulse delay was noted during his routine physical examination. A 70-mmHg systolic blood.

关键词： Aortic occlusion coarctation of the aorta Congenital heart disease

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Ascending Aortic Aneurysm and Dissection Secondary to Bicuspid Aortic Valve with Concomitant coarctation of Descending aorta Successfully Repaired with Extracorporeal Membrane Oxygenation Support: A Case Report

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Cardiology Discovery 2022年第2期2卷 124-126页

作者： Qin Jiang Juan Du Tao Yu Xiaobo Huang Mingliang Zuo Keli Huang Department of Cardiac Surgery Sichuan Provincial People’s HospitalAffiliated Hospital of University of Electronic Science and TechnologyChengduSichuan 610072China Department of Operating Room Sichuan Provincia People’s HospitalAffiliated Hospital of University of Electronic Science and TechnologyChengduSichuan 610072China Department of Surgical Intensive Care Unit Sichuan Provincia People’s HospitalAffiliated Hospital of University of Electronic Science and TechnologyChengduSichuan 610072China Department of Medica Ultrasonics Sichuan Provincia People’s HosptalAffiliated Hospital of University of Electronic Science and TechnologyChengduSichuan 610072China

Type A aortic aneurysm and dissection secondary to bicuspid aortic valve(BAV)with untreated coarctation of the aorta(CoA)in adults is a rare finding because there are almost no“abnormalities”in these patients’medical ***,we report on a 47-year-old man with unexplained weakness followed by *** was diagnosed with cardiogenic shock and underwent venoarterial extracorporeal membrane oxygenation(VA-ECMO).BAV,ascending aortic aneurysm and dissection(based on bedside echocardiography)and concomitant CoA(based on computed tomography angiography)were *** patient then underwent emergency surgery including aortic root replacement with a composite mechanical valve conduit,additional ascending-to-descending aortic bypass,and coronary artery bypass grafting with a saphenous vein graft to the right coronary *** treatment,he recovered ***,here we present a case involving a patient in a critical condition with ascending aortic aneurysm and dissection secondary to complex congenital heart defects,who was successfully treated with composite surgical procedures combined with life-saving VA-ECMO.

关键词： Aortic aneurysm Dissection Bicuspid aortic valve Case report coarctation of the aorta Extracorporeal membrane oxygenation

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Fetal Endocardial Fibroelastosis with coarctation of Aortic Arch: A Case Report

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Case Reports in Clinical Medicine 2022年第5期11卷 194-199页

作者： Jing Ding Biaohu Liu Biyun Sun Yun Hong Department of Ultrasound Medicine Yijishan Hospital Wannan Medical College Wuhu China

This study describes a 34-year-old pregnant woman who underwent prenatal echocardiography at 24 weeks of gestation and found fetal heart abnormalities. She underwent fetal echocardiography in our hospital. Echocardiography showed complex malformation of fetal heart, thickening and calcification of left ventricular myocardium and tendon, weakening or even flattening of left ventricular wall movement, very severe mitral stenosis, severe mitral regurgitation, aortic stenosis, narrowing of the aortic arch, countercurrent of the ductal arch to aortic arch, small diameter of the oval foramen and significantly increased flow velocity. The patient decided to induce labor after expert consultation, but no autopsy was performed due to his family’s refusal. Color Doppler ultrasound can find the positive signs of endocardial elastofibroplasia earlier, and accurately diagnose patients with neonatal elastofibroplasia. It provides accurate diagnostic information for the clinic and can be used as the first choice. This report has obtained the informed consent of its parents.

关键词： Endocardial Fibroelastosis coarctation of the aorta Prenatal Ultrasound Diagnosis

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