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Tilapia Lake Virus(TiLV)disease:Current status of understanding

Aquaculture and Fisheries 2022年第1期7卷 7-17页

作者： Nilav Aich Anirban Paul Tanmoy Gon Choudhury Himadri Saha Department of Fisheries Government of TripuraTripura799006India ICAR-Central Institute of Freshwater Aquaculture KausalyagangaBhubaneswar751002India Department of Aquatic Health&Environment College of FisheriesCentral Agricultural University(Imphal)LembucherraTripura799210India

Tilapia Lake Virus(TiLV)disease is an emerging and transboundary disease of tilapia cultures,causing mortality up to 90%*** is a negative sense single stranded RNA virus belongs to family Amnoonviridae,genus Tilapinevirus and species Tilapia *** first TiLV outbreak to fishes was reported from Israel followed by other countries viz.,Ecuador,colombia,Egypt,Thailand,Chinese Taipei,India,Malaysia,Bangladesh,Uganda,Tanzania,Peru,Mexico,Philippines,Indonesia,and *** the life stages of Tilapia(belonging to the family Cichlidae)are vulnerable to TiLV ***,river barb and giant gourami have also been found susceptible to TiLV *** virus infects the vital organs of the fish,including eyes,brain,and *** notable pathological finding of this disease includes syncytial cell formation and massive hepatocellular necrosis with pyknotic and karyolytic nuclei in the liver cells of infected *** disease is very contagious and spreads through both horizontal and vertical *** sensitive and rapid molecular diagnostic tools like reverse transcriptase polymerase chain reaction(RT-PCR),RT-quantitative PCR(RT-qPCR),loop-mediated isothermal amplification(LAMP)have been developed for early detection of the *** date,no comprehensive control measures have been developed throughout the globe,although aggressive work on this line is going *** of strict good management practices,including quarantine protocols,are the only available option to combat the outbreak and spread of the *** review emphasizes the etiology,occurrence and distribution,mode of transmission,pathology and pathogenesis,diagnosis,possible control measures,and challenges of TiLV disease.

关键词： co-habitation Diagnosis Tilapinevirus Syncytial Tilapia lake virus

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