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Optimized cutoff maternal age for adverse obstetrical outcomes: a multicenter retrospective cohort study in Urban China during 2011 to 2012

引用

Chinese Medical Journal 2020年第3期133卷 269-276页

作者： Xiao-Lei Zhang Huan Liang Huan-Qiang Zhao Su-Wen Wu Qiong-Jie Zhou Xiao-Tian Li Department of Obstetrics Obstetrics and Gynecology Hospital of Fudan UniversityShanghai 200011China Shanghai Key Laboratory of Female Reproductive Endocrine-Related Diseases Shanghai 200011China Women’s Health and Perinatology Research Group Department of Clinical MedicineUiT-the Arctic University of NorwayTromso 9037Norway Institute of Biomedical Sciences Fudan UniversityShanghai 200032China.

Background:China’s two-child policy has led to a trend of aging in pregnancy which was associated with adverse *** study aimed to identify the clinically cutoff maternal age for adverse obstetric outcomes in ***:This secondary analysis of a multicenter retrospective cohort study included data of childbearing women from 39 hospitals collected in urban China during 2011 to *** regression was used to assess the adjusted odds ratios(aOR)of adverse outcomes in different age groups in comparison to women aged 20 to 24 *** adjustments included the location of the hospital,educational level,and residence *** cutoff age was defined as the age above which the aOR continuously become both statistically(Pclinically(aOR>2)***:Overall,108,059 women were *** primiparae,clinically cutoff maternal ages for gestational diabetes(aOR:2.136,95%confidence interval[CI]:1.856-2.458,Pclinically cutoff ages for gestational diabetes(aOR:2.977,95%CI:1.808-4.904,P<0.001),hypertensive disorder(aOR:2.555,95%CI:1.836-3.554,P<0.001),cesarean section(aOR:2.224,95%CI:1.952-2.534,P<0.001),post-partum hemorrhage(aOR:2.140,95%CI:1.472-3.110,P<0.001),placenta previa(aOR:2.272,95%CI:1.375-3.756,P<0.001),macrosomia(aOR:2.215,95%CI:1.552-3.161,P<0.001),and neonatal asphyxia(aOR:2.132,95%CI:1.461-3.110,P<0.001)were 29,31,33,35,35,41,and 41 years,***:Early cutoff ages for gestational diabetes and cesarean section highlight a reasonable childbearing age in urban *** various optimized cutoff ages for different adverse pregnancy outcomes should be carefully

关键词： Maternal age Pregnancy outcomes clinical alarms Parity

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