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Effects of lavender and citrus aurantium on pain of conscious intensive care unit patients: A parallel randomized placebo-controlled trial

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Journal of Integrative Medicine 2021年第4期19卷 333-339页

作者： Zahra Karimzadeh Mansooreh Azizzadeh Forouzi Haleh Tajadini Mehdi Ahmadinejad Callista Roy Mahlagha Dehghan Department of Critical Care Nursing Razi Faculty of Nursing and MidwiferyKerman University of Medical SciencesKerman ***Iran Neuroscience Research Center Institute of NeuropharmacologyKerman University of Medical SciencesKerman ***Iran Department of Traditional Medicine Faculty of Traditional MedicineKerman University of Medical SciencesKerman ***Iran Department of Critical Care Medicine Kerman University of Medical SciencesKerman ***Iran Department of Nursing Mount Saint Mary's UniversityLos AngelesCA 90049USA Nursing Research Center Kerman University of Medical SciencesKerman ***Iran

Background: Conscious patients admitted to intensive care units(ICUs) suffer from pain for various reasons, which can affect their recovery process.Objective: The present study compared the effects of aromatherapy with citrus aurantium and lavender essential oils against placebo for reducing pain in conscious intensive care patients.Design, setting, participants and interventions: This study was a parallel randomized placebo-controlled trial. The ICUs of two educational hospitals in Kerman in Southeastern Iran were the study setting.One hundred and fifty conscious intensive care patients were randomly divided into three groups using a stratified block randomization method. Two groups received aromatherapy with essential oils: one with lavender and the other with C. aurantium;these patients received a 30-minute therapy session using their assigned essential oil on the second day of their intensive care stay. The placebo group used 5 drops of normal saline instead of essential oil during their session.Main outcome measures: Patient’s pain was assessed using a visual analog scale before the aromatherapy intervention, as well as immediately after and one and three hours after intervention.Results: The mean pain score of the lavender group was 40.01 before the aromatherapy intervention and fell to 39.40, 30.60 and 23.68 immediately after the intervention, and at hour one and three postintervention, respectively. The mean pain score of the C. aurantium group was 45.48 before the intervention and was reduced to 32.34 at three hours after the intervention. The mean pain of the placebo group decreased from 42.80 before the intervention to 35.20 at three hours after the intervention. Pain scores of all groups decreased during the study(P < 0.001). The mean pain of the lavender group was significantly lower than that of the placebo group at three hours after the intervention.Conclusion: The results of this study showed that aromatherapy with lavender essential oil reduced pain in conscious ICU patients. Our data could not j

关键词： Pain Lavender citrus aurantium Intensive care Aromatherapy

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Essential Oil from citrus aurantium Alleviates Anxiety of Patients Undergoing Coronary Angiography: A Single-Blind, Randomized Controlled Trial

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Chinese Journal of Integrative Medicine 2021年第3期27卷 177-182页

作者： Khalil Moradi Hossein Ashtarian Nicholas Yakubu Danzima Hamid Saeedi Behrouz Bijan Farzaneh Akbari Mohammad Mehdi Mohammadi Intensive Care Unit Imam Reza HospitalKermanshah University of Medical SciencesKermanshahIran Health Education Department Health SchooKermanshah University of Medical SciencesKerm anshahIran School of Nursing and Micwilery Tehran University of Medical SciencesTehranIran Student Research Comite School of NursingTabriz University of Medical SciencesTabrizIran

Objective To determine the effectiveness and safety of essential oil from citrus aurantium on anxiety in patients undergoing coronary angiography.Methods A single-blind,randomized controlled trial was conducted in 80 patients experiencing coronary angiography in Imam Ali Hospital in Kermanshah,Iran from April to November in 2016.All patients were randomly divided into intervention and control groups by a random number table,40 cases in each group.The patients in the intervention group inhaled citrus aurantium essential oil for 15–20 min about 60 min before angiography.Following the same procedure,distilled water was used instead of citrus aurantium in the control group.Spielbergers State-Trait Anxiety Inventory(STAI)was filled in and vital signs including systolic blood pressure(SBP),diastolic blood pressure(DBP),respiratory and pulse rate were recorded before and 20 min after the intervention.Adverse reactions after intervention were observed.Results In the intervention group,the mean scores of STAI,SBP,DBP,respiratory and pulse rate were 53.30±10.13,134.82±11.75 mm Hg,84.49±6.99 mm Hg,17.87±1.73 times/min,and 76.48±12.55 beats/min at baseline and significantly decreased to 42.37±10.15,124.49±10.48 mm Hg,79.23±6.62 mm Hg,14.54±1.43 times/min,and 70.03±13.66 beats/min respectively 20 min after intervention(all P0.05).All subjects reported no adverse reactions.Conclusion Inhalation of the essential oil from citrus aurantium was effective in reducing anxiety and stress levels in patients undergoing coronary angiography.

关键词： single-blind randomized controlled trial essential oil citrus aurantium anxiety coronary angiography non-drug treatment aromatherapy

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Strategic Conservation of Orchard Germplasm Based on Indigenous Knowledge and Genetic Diversity:a Case Study of Sour Orange Populations in China

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Journal of Integrative Plant Biology 2009年第1期51卷 100-106页

作者： Feng Ming Qi-Kun Liu Jin-Lei Shi Wei Wang Bao-Rong Lu Institute of Genetics State Key Laboratory of Genetic Engineering Fudan University Shanghai 200433 China Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering Institute of Biodiversity Science Fudan University Shanghai 200433 China

To effectively conserve sour orange （citrus aurantium L.） germplasm on two islands at the estuary of the Yangtze River in China, we estimated genetic variation and relationships of the known parental trees and their proposed descendents （young trees） using the fingerprints of random amplified polymorphic DNA （RAPD）. Results based on RAPD analyses showed considerable genetic diversity in the parental populations （He = 0.202）. The overall populations including the parental and young trees showed slightly higher genetic diversity （He = 0.298） than the parents, with about 10% variation between populations. An unweighted pair group method with arithmetic mean analysis dendrogram based on cluster analysis of the Jaccard similarity among individuals demonstrated a more complicated relationship of the parental and young trees from the two islands, although the young trees showed a clear association with parental trees. This indicates a significant contribution of parental trees in establishing the sour orange populations on the two islands. According to farmers＇ knowledge, conservation of only one or two parental trees would be sufficient because they believed that the whole populations were generated from a single mother tree. However, this study suggests that preserving most parental trees and some selected young trees with distant genetic relationships should be an effective conservation strategy for sour orange germplasm on the two islands.

关键词： citrus aurantium genetic conservation orchard genetic resources random amplified polymorphic DNA variation relationship.

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