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Prevalence of occult HBV infection in haemodialysis patients with chronic hcv

World Journal of Gastroenterology 2006年第21期12卷 3420-3424页

作者： Vedat Goral Hamza Ozkul Selahattin Tekes Dede Sit Ali Kemal Kadiroglu Department of Gastroenterology Dicle University School of Medicine DiyarbakirTurkey Department of Internal Medicine Dicle University School of Medicine DiyarbakirTurkey Department of Molecular Biology Dicle University School of Medicine DiyarbakirTurkey Department of Nephrology Dicle University School of Medicine DiyarbakirTurkey

AIM： To study the prevalence and clinical effects of occult HBV infection in haemodialysis patients with chronic ***： Fifty chronic hemodialysis patients with negative HbsAg, and positive anti-hcv were included in the study. These patients were divided into two groups： hcv-RNA positive and hcv-RNA negative, based on the results of hcv-RNA PCR. HBV-DNA was studied using the PCR method in both ***： None of the 22 hcv-RNA positive patients and 28 hcv-RNA negative patients revealed HBV-DNA in serum by PCR method. The average age was 47.2±17.0 in the hcv-RNA positive group and 39.6±15.6 in the hcv-RNA negative ***： The prevalence of occult HBV infection is not high in haemodialysis patients with chronic hcv in our region. This result of our study has to be evaluated in consideration of the interaction between HBsAg positivity （8%-10%） and frequency of HBV mutants in our region.

关键词： chronic hcv Haemodialysis Occult HBV infection

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Impact of Gender Difference on Characteristics and Outcome of chronic Hepatitis C

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Open Journal of Gastroenterology 2020年第11期10卷 281-294页

作者： Mahmoud Saif-Al-Islam Hamdy Saad Mohamed Mustafa Adel Younis Mahmoud Yosef Abdelhamid Magda Mohamed Ali Safaa Khalaf Departments of Tropical Medicine and Gastroenterology Sohag University Hospital Sohag Egypt Departments of Internal Medicine Sohag University Hospital Sohag Egypt Departments of Clinical Pathology Sohag University Hospital Sohag Egypt Departments of Radiology Sohag University Hospital Sohag Egypt Departments of Community Medicine Sohag University Hospital Sohag Egypt

Gender difference in chronic hepatitis C (CHC) infection is not previously well studied. We aimed to analyze the effect of gender difference on the risk factors of CHC, disease progression, and outcome after oral direct acting antiviral (DAA) therapy. The study was conducted at Tropical Medicine and Gastroenterology Department, Sohag University, Egypt, in the period between 2018 and 2020. 775 patients were evaluated for hepatitis C virus (HCV) risk factors. Laboratory investigations, abdominal ultrasound and liver Shear wave elastography (SWE) were done. The patients were given antiviral therapy and followed up to assess the response and side effects of DAA therapy. 434 (56%) of study patients were males and 341 (44%) were females. Catching infection from blood transfusion and intravenous (IV) injection of tarter emetic was significantly higher in males, while catching infection from surgical operation was significantly higher in females. Hepatic fibrosis was significantly more extensive in males. Side effects were reported more in females. Sustained virological response (SVR) 12 was reported in 98.6%. Females had a slightly better SVR12 than males (99.4% versus 97.9%). In conclusion males were different from females in exposure to hcv risk factors. After introduction of blood screening and

关键词： chronic hcv Risk Factors Gender Difference DAA Therapy

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