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chronic eosinophilic pneumonia with mucous plugs:case report

Chinese Medical Journal 2006年第3期119卷 262-264页

作者： XIE Li-xin MO Guo-xin CHEN Liang-an LIU You-ning Department of Respiratory Medicine General Hospital of PLABeijing 100853 China

chronic eosinophilic pneumonia （CEP）, a rare eosinophilic lung disease of unknown etiology,is characterized by peripheral blood eosinophilia, chest radiograph infiltrates, and prompt response to corticosteroid therapy. The first detailed description of CEP was described by Carrington et al in 1969. The usual symptoms are cough, dyspnea, fever, and weight loss. It is most often seen in middle aged woman and has a subacute onset. We report a case of CEP presenting with right lower lung infiltrates and mucus plugging that causing bronchus obstruction.

关键词： chronic eosinophilic pneumonia mucous plug transbronchial lung biopsy

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A case of sarcoidosis associated with chronic eosinophilic pneumonia

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Case Reports in Clinical Medicine 2014年第2期3卷 89-91页

作者： Halil Yanardag Cuneyt Tetikkurt Asli Sezgin Ertugrul Oruc Muammer Bilir Department of Internal Medicine Cerrahpasa Medical FacultyIstanbul UniversityIstanbulTurkey Department of Pulmonary Diseases Cerrahpasa Medical FacultyIstanbul UniversityIstanbulTurkey Department of Pathology Cerrahpasa Medical FacultyIstanbul UniversityIstanbulTurkey

A 78-year-old woman was referred to our university hospital due to dry cough, fever, and weight loss. Laboratory revealed blood eosinophilia, high ESR, CRP and LDH. Rheumatologic markers were negative. Chest X-ray showed ground glass opacities in upper lobes. Uveitis developed in the left eye 1 week after admission. Thorax CT revealed ground glass opacities, reticular appearence in the upper lobes, enlarged axillary and mediastinal lymph nodes. Bronchoalveolar lavage CD4/CD8 was 2.1 and had 48% eosinophils. Histopathologic examination revealed eosinophilic infiltration and non-caseating epitheloid granulomas in the lung and mediastinal lymph nodes without vasculitis. Symptoms, blood eosinophilia and initial thorax CT findings improved after two months of methylprednisolone treatment. chronic eosinophilic pneumonia is a rare disease characterized by systemic and pulmonary manifestations. It may be associated with other diseases.

关键词： Sarcoidosis chronic eosinophilic pneumonia Pulmonary Eosinophilia

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