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chinese medicine plaster as A New Treatment for Surgical Site Infection in Patients with Cesarean Delivery:A Randomized,Double-Blind,Controlled Trial

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chinese Journal of Integrative medicine 2023年第6期29卷 483-489页

作者： HAN Guan-ya WU Xiao-li LI Dong-mei CAI Hai-rui ZHOU Jun-jun HE Xiao-bo Department of Obstetrics Ningbo Women and Children's HospitalNingboZhejiang Province(315012)China Department of Medical Intensive Care Unit Ningbo Women and Children's HospitalNingboZhejiang Province(315012)China

Objective To evaluate the efficacy of chinese plaster containing rhubarb and mirabilite on surgical site infection(SSI)in patients with cesarean delivery(CD)by performing a randomized controlled trial.Methods This randomized controlled trial included 560 patients with CD due to fetal head descent enrolled at a tertiary teaching center between December 31,2018 and October 31,2021.Eligible patients were randomly assigned to a chinese medicine(CM)group(280 cases)or a placebo group(280 cases)by a random number table,and were treated with CM plaster(made by rhubarb and mirabilite)or a placebo plaster,respectively.Both courses of treatment lasted from the day 1 of CD,followed day 2 until discharge.The primary outcome was the total number of patients with superficial,deep and organ/space SSI.The secondary outcome was duration of postoperative hospital stay,antibiotic intake,and unplanned readmission or reoperation due to SSI.All reported efficacy and safety outcomes were confirmed by a central adjudication committee that was unaware of the study-group assignments.Results During the recovery process after CD,the rates of localized swelling,redness and heat were significantly lower in the CM group than in the placebo group[7.55%(20/265)vs.17.21%(47/274),Pplaster containing rhubarb and mirabilite had an effect on SSI.It is safe for mothers and imposes lower economic and mental burdens on patie

关键词： chinese medicine plaster rhubarb and mirabilite surgical site infection cesarean delivery randomizedcontrolledtrial

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