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Single-site Baseline and Short-term Outcomes of Clinical Characteristics and Life Quality Evaluation of chinese Wet Age-related Macular Degeneration Patients in Routine Clinical Practice

引用

chinese Medical Journal 2015年第9期128卷 1154-1159页

作者： Li-Li Wang Wen-Jia Liu Hai-Yun Liu Xun Xu Department of Ophthalmology Shanghai First People@s Hospital Shanghai 200080 China

Background：Age-related macular degeneration （AMD） is the leading cause of irreversible vision loss among the older *** China,treatment of age-related ocular diseases is becoming a priority in eye care *** study was to investigate the clinical characteristics and quality of life of chinese patients with wet AMD and current treatment types,to evaluate short-term gains in different treatments,and to investigate associations between visual function and vision-related quality of life （VRQoL）.Methods：A prospective,observational,noninterventional study was *** data were collected from patients with clinical diagnoses of wet AMD before clinical assessments at *** was measured with the chinese version of the national eye institute visual function questionnaire-25 （NEI VFQ-25）.Correlations of the NEI VFQ-25 subscale scores with best-corrected visual acuity （BCVA） and between-group differences were ***：A total of 80 wet AMD patients were enrolled,with the mean age of 68.40 *** one-quarter ofwetAMD patients received intravitreal （IVT） ranibizumab treatment,and 67％ of them were treated on apro re nata *** visual acuity of patients treated with IVT ranibizumab at month 3 after treatment was significantly increased,whereas patients treated with traditional chinese medicine achieved no significant ***＇s α for the NEI VFQ-25 subscales ranged from 0.697 to *** subscale and overall composite scores were moderately correlated with the BCVA of the better-seeing *** differences in the overall NEI VFQ-25 scores and other subscales were observed between patients with BCVA in the better-seeing eye of less than 50 letters and the ***：Patients treated with IVT ranibizumab experienced better vision improvement at short-term *** chinese version of the NEI VFQ-25 is a valid and reliable tool for assessing the VRQoL of chinese wet AMD patients.

关键词： chinese version of national eye institute visual function questionnaire-25 Ranibizumab Vision-related Quality of Life Wet Age-related Macular Degeneration

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