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Noise and delay sustained chimera state in small world neuronal network

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Science China(Technological Sciences) 2019年第7期62卷 1134-1140页

作者： TANG Jun ZHANG Juan MA Jun LUO JinMing School of Physics China University of Mining and Technology Xuzhou 221116 China Department of Physics Lanzhou University of Technology Lanzhou 730050 China School of Mathematics China University of Mining and Technology Xuzhou 221116 China

chimera state in neuronal network means the coexistence of synchronized and desynchronized firing patterns. It attracts much attention recently due to its possible relevance to the phenomenon of unihemispheric sleep in mammals. In this paper, we search for chimera state in a noisy small-world neuronal network, in which the neurons are delayed coupled. We found both transient and permanent chimera state when time delay is close to a critical value. The chimera state occurs due to the competition between the synchronized and desynchronized patterns in the neuronal network. On the other hand, intermediate intensity of noise facilitates the occurrence of delay-sustained chimera states. Comparison between noise and delay shows that time delay is the key factor determining the chimera state, whereas noise is a subordinate one.

关键词： delay noise chimera state neuronal network

Construction,Expression,and Characterization of a Recombinant Annexin B1-Low Molecular Weight Urokinase chimera in Escherichia coli

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Acta Biochimica et Biophysica Sinica 2004年第3期36卷 184-190页

作者： Hong-Li YAN, Wei-Ting WANG1, Yan HE , Zhuan-You ZHAO1,Yuan-Jian GAO, Yi ZHANG, and Shu-Han SUN Department of Medical Genetics, Second Military Medical University, Shanghai 200433, China 1Department of Pharmacology, Tianjin Institute of Medicine, Tianjin 300193, China Department of Medical Genetics Second Military Medical University Shanghai 200433 China Department of Pharmacology Tianjin Institute of Medicine Tianjin 300193 China

To produce a thrombi-targeting plasminogen activator, low molecular weight single-chain urokinase gene (scuPA32k) was spliced with the full-length cDNA of annexin B1 gene (anxB1) by overlap extension method. The fused gene anxB1scuPA was ligated into pET28a vector, transformed into E. coli BL21-RIL, and then induced to express under the control of T7 promoter. The AnxB1ScuPA protein ex- pressed amounted to 22% of the total bacterial proteins. The product was refolded, and then purified by using DEAE Sepharose fast flow ion-exchange column and Superdex S-200 gel-filtration column. HPLC analysis revealed that the final purity is about 95%. The specific activity of AnxB1ScuPA, measured as amidolytic activity, reached 100,000 IU/mg. It had a similar S2444 catalytic efficiency (kcat/Km) to ScuPA32k, and also showed high activated-platelet membrane-binding activity and anticoagulant activity, indicating that the chi- mera fully retained the components of enzymatic and membrane-binding activities of the parent molecules. In vivo test revealed that, the dogs administered with AnxB1ScuPA had less reperfusion time, higher reperfu- sion ratio, and less bleeding effects than those with urokinase. These findings indicated that AnxB1ScuPA might have advantages over current available thrombolytic agents.

关键词： annexin B1 thrombolytic agent low molecular weight single-chain urokinase chimera

Utilization of central disk of blastoderm and germinal crescent region of interspecific germline chimera between chicken and quail

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Asian Journal of Andrology 2002年第2期4卷 83-86页

作者： TomokiSoh YukioKato 等 FacultyofAgriculture GraduateSchoolKyushuUniversityFukuoka812－8581Japan FacultyofAgriculture MeijiUniversityKawasaki214－8571Japan

OBJECTIVE:The production of interspecific germline chimeras between chicken and quail were attempted employing the dissociated cells derived from the blastodermal central disk (stage X) and the germinal crescent region of embryo (stage 7-8).;METHODS:The central disk (CD) of the area pellucida in chicken blastoderm (stage X) and the germinal crescent region (GCR) of embryo (stage 7-8) were dispersed and injected into the subgerminal cavity of quail blastoderm (stage X). Injected eggs were incubated for 7 days or to hatching. The donor chicken DNA was detected by the polymerase chain reaction.;RESULTS:In day-7 embryos, chicken DNA was detected in 5 gonads and 9 brains from 53 survived embryos received chicken CD cells, and 1 gonads and 6 brains from 27 survived embryos received chicken GCR. Chicken DNA was also detected from the semen of one adult male hatched from eggs received chicken GCR cells.;CONCLUSIONS:CD and GCR cells as the donors showed the possibility to produce the interspecific germline chimera, but further studies are needed to make necessary improvement.

关键词： Chicken chimera Germline Polymerase chain reaction Quail Semen

Dispersion Analysis of Ranging-Code Markers Applied to Beidou B1C Signal Based on chimera

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Dispersion Analysis of Ranging-Code Markers Applied to Beido...

The Parody of Characters in John Barth’s chimera

第十三届中国卫星导航年会

作者： Huanyu Wang Xiaomei Tang Muzi Yuan Gang Ou National University of Defense Technology

At present, in order to improve the security capabilities of the civil navigation signal system, both Galileo and GPS have proposed a navigation signal authentication scheme. However, there is no civil official navigation signal authentication scheme for Beidou Navigation System, so it is necessary to propose a navigation signal authentication scheme suitable for Beidou signal system. This paper is mainly to prepare for the subsequent research on the navigation signal authentication scheme adapted to Beidou B1 C signal. chimera is applied to Beidou B1 C signal to study the impact of the dispersion of markers. In this paper, by setting other parameters constant, define the markers’ dispersion. Under circumstances of different dispersion, research the collision probability of the segment and the correlation performance of the encrypted ranging code. Draw the following conclusion that the dispersion of markers rarely affects the correlation performance. While the dispersion is higher, the collision probability of the segment will be greater. In the design of spreading code authentication scheme, it is sufficient to determine the dispersion of markers from the perspective of the collision probability of the segment.

关键词： chimera Beidou B1C signal Dispersion of Markers

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海外英语 2019年第17期 199-200页

作者：谢昕烨 Changzhou Liu Guojun Vocational Technology College

John Barth uses a lot of parody in chimera,such as characters,story background,*** the analysis of character parody,we can feel the timeliness and reality of that period.

关键词： Parody chimera Characters

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介绍一款优秀的分子图形软件chimera

化工时刊 2011年第10期25卷 47-48页

作者：仝艳李晓晓李晓飞河南中医学院药学院河南郑州450008

为提高信息技术在化学科研教育中的应用,介绍了一款名为UCSF chimera的优秀的分子图形软件,其自由的可视化功能及其他附属工具使用方便,在生物、医药、化学的科研、教育等方面都有着广泛的用途。

关键词： chimera 多媒体蛋白质图形软件

一种基于chimera软件的分子动力学模拟方法

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科学技术创新 2021年第13期 61-63页

作者：马学婧李俊甫宋立立张兆英王悦孙琳琳沧州师范学院生命科学学院河北沧州061001

chimera是用于分子结构和相关数据的交互式可视化和分析程序,可实现的功能有密度图,轨迹和序列比对等。然而,目前对于其在分子动力学模拟方面的应用还没有详细的阐述。因此,本文拟详细介绍应用chimera软件进行分子动力学模拟的流程,这... 详细信息

chimera是用于分子结构和相关数据的交互式可视化和分析程序,可实现的功能有密度图,轨迹和序列比对等。然而,目前对于其在分子动力学模拟方面的应用还没有详细的阐述。因此,本文拟详细介绍应用chimera软件进行分子动力学模拟的流程,这将促进其在生物、医药、化学的科研、教育等方面的应用进而推动这些领域的发展。

关键词： chimera 图形软件蛋白质分子动力学模拟

分子图形显示软件chimera在有机化学多媒体教学中的应用

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分子图形显示软件Chimera在有机化学多媒体教学中的应用

The Parody of Plots in John Barth's chimera

第十一届全国计算（机）化学学术会议

作者：仝艳李晓飞王宪玲河南中医学院药学院

＜正＞分子图形显示软件chimera是-个免费的交互式分子模型显示程序,由加州大学旧金山分校开发,功能强大,对与个人、学术等非营利机构使用免费。其强大的分子图形显示功能以及自由的交互式功能尤其适用于有机化学多媒体教学,也为有机化... 详细信息

＜正＞分子图形显示软件chimera是-个免费的交互式分子模型显示程序,由加州大学旧金山分校开发,功能强大,对与个人、学术等非营利机构使用免费。其强大的分子图形显示功能以及自由的交互式功能尤其适用于有机化学多媒体教学,也为有机化学多媒体素材的准备以及交互式动画的制作提供了极大便利。

关键词： chimera 多媒体教学蛋白质

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海外英语 2019年第5期 201-201页

作者：谢昕烨 Changzhou Liu Guojun Vocational Technology College

John Barth uses a lot of parody in chimera,such as plots,characters,*** article will compare the plot between chimera and the originals,to interpret the imitation and mockery of parody.

关键词： Parody chimera Plot