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Effects of Multiple Cleaning and Disinfection Interventions on Infectious Diseases in children: A Group Randomized Trial in China

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Biomedical and Environmental Sciences 2015年第11期28卷 779-787页

作者： BAN Hai Qun LI Tao SHEN Jin LI Jin PENG Pin Zhang YE Heng Ping ZHANG Liu Bo Institute of Environment Health and Related Product Safety Center for Disease Control and Prevention of China Center for Disease Control and Prevention of Xiantao city

Objective To assess the effectiveness of multiple cleaning and disinfection interventions in the homes and kindergartens, in reducing gastrointestinal and respiratory illnesses of children. Methods From October 2010 to September 2011, we performed a prospective, controlled study in China. 408 children under 5 years old were recruited and group randomized into intervention and control groups. Families and kindergartens in the intervention group were provided with antibacterial products for hand hygiene and surface cleaning or disinfection for one year. Each child＇s illness symptoms and sick leave were recorded every day. Results A total of 393 children completed the study, with similar baseline demographics in each of the 2 groups. Except for abdominal pain, the odds of symptoms （fever, cough and expectoration, runny nose and nasal congestion, diarrhea）, illness （acute respiratory illness and gastrointestinal illness）, and sick leave per person each month were significantly reduced by interventions. The rates of fever, diarrhea, acute respiratory illness, gastrointestinal illness and sick leave per person per year were significantly decreased as well. Conclusion Not only the acute respiratory children were significantly reduced by multiple and gastrointestinal illness but the sick leave rate in interventions.

关键词： Communicable disease control child daycare centers Sick leave Antibacterial agents Hand hygiene Domestic hygiene Surface cleaning Surface disinfection

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