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Primary localized gastric amyloidosis:A scoping review of the literature from clinical presentations to prognosis

World Journal of Gastroenterology 2021年第12期27卷 1132-1148页

作者： Xin-Yu Lin Dan Pan Li-Xuan Sang Bing Chang Department of Neurology The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Geriatrics The First Affiliated Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Gastroenterology The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina

Localized gastric amyloidosis(LGA)is a rare disease characterized by abnormal extracellular deposition of amyloid protein restricted to the stomach and it is confirmed by positive results of Congo red *** decades,only a few cases have been reported and studies or research focusing on it are *** LGA has a low incidence,patients may suffer a lot from it and require proper diagnosis and ***,the pathology of LGA remains unknown and no overall review of LGA from its presentations to its prognosis has been *** with LGA are often asymptomatic or manifest atypical symptoms,making it difficult to differentiate from other gastrointestinal ***,we report the case of a 70-year-old woman with LGA and provide an overview of case reports of LGA available to *** on that,we conclude current concepts of clinical manifestations,diagnosis,treatment,and prognosis of LGA,aiming at providing a detailed diagnostic procedure for clinicians and promoting the guidelines of *** addition,a few advanced technologies applied in amyloidosis are also discussed in this review,aiming at providing clinicians with a reference of diagnostic *** this review,we hope to raise awareness of LGA among the public and clinicians.

关键词： Gastroscopy changes of gastric mucosa Primary localized gastric amyloidosis Clinical presentations Prognosis

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