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Robust restoration of low-dose cerebral perfusion ct images using NCS-Unet

Nuclear Science and Techniques 2022年第3期33卷 62-76页

作者： Kai Chen Li-Bo Zhang Jia-Shun Liu Yuan Gao Zhan Wu Hai-Chen Zhu Chang-Ping Du Xiao-Li Mai Chun-Feng Yang Yang Chen Southeast University Nanjing 210096China School of Cyber Science and Engineering Southeast UniversityNanjing 210096China Key Laboratory of Computer Network and Information Integration(Southeast University) Ministry of EducationNanjing 210096China Department of Radiology General Hospital of the Northern Theater of the Chinese People’s Liberation ArmyShenyang 110016China Laboratory of Image Science and Technology The School of Computer Science and EngineeringSoutheast UniversityNanjing 210096China Department of Radiology Nanjing Drum Tower HospitalThe Affiliated Hospital of Nanjing University Medical SchoolNanjing 210008China Jiangsu Key Laboratory of Molecular and Functional Imaging Department of RadiologyZhongda HospitalSoutheast UniversityNanjing 210009China Jiangsu Provincial Joint International Research Laboratory of Medical Information Processing School of Computer Science and EngineeringSoutheast UniversityNanjing 210096China

cerebral perfusion computed tomography(Pct)is an important imaging modality for evaluating cerebrovascular diseases and stroke *** widespread public concern about the potential cancer risks and health hazards associated with cumulative radiation exposure in Pct imaging,considerable research has been conducted to reduce the radiation dose in X-ray-based brain perfusion *** the dose of X-rays causes severe noise and artifacts in Pct *** solve this problem,we propose a deep learning method called *** exceptional characteristics of non-subsampled contourlet transform(NSct)and the Sobel filter are introduced into *** decomposes the convolved features into high-and low-frequency *** decomposed high-frequency component retains image edges,contrast imaging traces,and noise,whereas the low-frequency component retains the main image *** Sobel filter extracts the contours of the original image and the imaging traces caused by the contrast agent *** extracted information is added to NCS-Unet to improve its performance in noise reduction and artifact *** and quantitative analyses demonstrated that the proposed NCS-Unet can improve the quality of low-dose cone-beam ct perfusion reconstruction images and the accuracy of perfusion parameter calculations.

关键词： cerebral perfusion ct Low-dose Image denoising perfusion parameters

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