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Lesser celandine(pilewort) induced acute toxic liver injury: The first case report worldwide

World Journal of Hepatology 2015年第2期7卷 285-288页

作者： Bulent Yilmaz Bar?? Yilmaz Bora Akta? Ozan Unlu Emir Charles Roach Department of Gastroenterology School of Medicine Hacettepe University Department of Gastroenterology Diskapi Yildirim Beyazit Education and Research Hospital

Lesser celandine, also known as Ranunculus ficaria, is a herbaceous perennial plant that commonly utilizes piles and is taken either internally or used *** causality assessment of several reports provided evidence for the existence of Greater celandine hepatotoxicity. However, there hasn't been any case report published thus far, about lesser celandine induced liver injury. Here, we present a case of 36-year-old woman admitted to the hospital with acute hepatitis and jaundice on her sclera with no history of drug abuse or alcohol consumption. However, the patient had a recent history of lesser celandine extract consumption for hemorrhoids, for about 10 d, prior to the admission. Viral hepatitis, autoimmune hepatitis, and drug induced toxic hepatitis were ruled out by further imaging studies and laboratory analysis. Using the Council for International Organizations of Medical Sciences scale, the type of liver injury was assumed as hepatocellular and was scored as 7 which shows probable causality. Immediate discontinuation of lesser celandine extract resulted in rapid decrease of the elevated enzymes. Herbs have been reported to cause liver injury and therefore should be suspected in the case of acute hepatitis with an unknown etiology. This case is important to be the first to explain hepatotoxicity caused by lesser celandine. Physicians should consider lesser celandine as a causative agent for hepatotoxicity.

关键词： celandine Acute liver toxicity Hepatitis Pilewort Herb

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Seasonal Distribution of Manganese in the Soil-Water-Plant in the Zone of Burshtyn Thermal Power Station

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Journal of Physical Science and Application 2014年第5期4卷 317-322页

作者： Ivan V. Mazepa Natalia V. Dovganich Maria A. Mazepa Vasyl Stefanyk Precarpathian National University lvano-Frankivsk 76025 Ukraine

This study deals with the impact of Burshtyn thermal power station on the amount of manganese in soil, water and celandine tissue. The research of manganese amount and form in the system： water-plant is of great importance due to active influence of thermal power station on the chemical structure of the polluted area. The changes in the amount and form of manganese in soil, water and plant are interrelated and depend on the season, the distance from the polluter and morph-functional plant structure, the cleaning system possibilities of the industrial enterprise and some meteorological factors.

关键词： Soil water celandine gross and changeable manganese amount Burshtyn thermal power station.

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