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Exposure to Hyaluronan and Radon-Containing Water during the Treatment of Periodontal Pockets

Journal of Biosciences and Medicines 2023年第12期11卷 203-217页

作者： Ani Gibishvili Mamuka Gogiberidze Marina Nikolaishvili Beritashvili Biomedicine Center Ivane Javakhishvili Tbilisi State University Tbilisi Georgia

Hyaluronic acid (HA) preparations have emerged as pivotal components in contemporary dentistry, gaining widespread recognition for their multifaceted roles in various biological functions. Extensive literature underscores the significance of HA in maintaining tissue water balance, fostering cell proliferation, promoting rapid cell migration, influencing cell differentiation during organism development, and facilitating tissue regeneration. Notably, HA’s interactions with cell surface receptors contribute to the viscosity of synovial fluid, activate the immune system, and enhance cartilage elasticity. Beyond these established functions, HA has also been investigated for its potential involvement in determining and studying the hormetic effects of radon water, adding a novel dimension to its applications in dental research. A thorough exploration of existing studies reveals a nuanced understanding of how HA interventions impact the outcomes of dental procedures. The comprehensive scope of these investigations allows for a more accurate assessment of the potential effectiveness of specific interventions and provides valuable insights into post-procedural prognoses for individual patients. This synthesis of literature serves as the foundation for elucidating the intricate interplay between HA, radon exposure, and their relevance in modern dental practices.

关键词： Hyaluronic Acid Dental Practice Biological Functions Tissue Water Balance Cell Proliferation Cell Migration Cell Differentiation Tissue Regeneration Synovial Fluid Viscosity Immune System Activation cartilage elasticity Radon Water Hormetic Effects Dental Research Intervention Effectiveness Post-Procedural Prognosis Risk Factors Inflammatory Periodontal Diseases Chronic Somatic Diseases Gastrointestinal Tract Disorders Respiratory Susceptibility Hereditary Predisposition Lifestyle Factors Smoking Dietary Preferences

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