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Quantification of carpaine and Antioxidant Properties of Extracts from Carica Papaya Plant Leaves and Stalks

Journal of Bioresources and Bioproducts 2021年第4期6卷 350-358页

作者： Jing Ying Yap Ching Lik Hii Sze Pheng Ong Kuan Hon Lim Faridah Abas Kar Yong Pin Future Food Malaysia Department of Chemical and Environmental EngineeringFaculty of Science and EngineeringUniversity of Nottingham MalaysiaJalan Broga43500 SemenyihSelangor Darul EhsanMalaysia School of Pharmacy Faculty of Science and Engineering University of Nottingham MalaysiaJalan Broga43500 SemenyihSelangor Darul EhsanMalaysia Department of Food Science Universiti Putra Malaysia43400 SerdangSelangor Darul EhsanMalaysia Forest Research Institute Malaysia 52109 Kuala LumpurSelangor Darul EhsanMalaysia

Significance increase in dengue cases have been recorded worldwide every year and South East Asian countries have been badly affected.Currently,antiviral drug to treat dengue is still not available but papaya leaves extract(PLE)have been successfully used in treating dengue patients.carpaine in PLE is the major active compounds that contributes to the anti-thrombocytopenic activity(raising platelet count in patient’s blood).The PLE also contains polyphenols that contribute to antioxidant properties.Studies were carried out to extract and quantify carpaine from young leaves,old leaves and stalks of papaya plant.carpaine crystalline powders were successfully purified and confirmed by ^(1)H and ^(13)C NMR(Nuclear Magnetic Resonance).Young papaya leaves recorded significantly higher amount of carpaine(Pcarpaine extracted from the young and old leaves and blended young leaves showed significantly much higher amount of carpaine as compared with the unblended samples(Pcarpaine for future development of drug in dengue treatment.

关键词： Antioxidants Carica papaya carpaine Dengue Total polyphenols

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