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Approach to cardiac masses: Thinking inside and outside the box

World Journal of Clinical Cases 2024年第28期12卷 6132-6136页

作者： Elia De Maria Chief of Arrhythmology Lab Cardiology UnitRamazzini HospitalCarpi 41012ModenaItaly

In this editorial we comment on the article by Huffaker et al,published in the current issue of the World Journal of Clinical *** masses encompass a broad range of lesions,potentially involving any cardiac structure,and they can be either neoplastic or *** cardiac tumors are rare,while metastases and pseudotumors are relatively *** masses frequently pose significant diagnostic and therapeutic *** imaging is fundamental for differential diagnosis,treatment,and surgical *** particular cardiac magnetic resonance(CMR)is currently the gold standard for noninvasive tissue *** allows evaluation of the relationship between the tumor and adjacent structures,detection of the degree of infiltration or expansion of the mass,and prediction of the possible malignancy of a mass with a high *** flow charts of diagnostic work-up have been proposed,based on clinical,laboratory and imaging findings,with the aim of helping physicians approach the problem in a pragmatic way(“thinking inside the box”).However,the clinical complexity of cancer patients,in particular those with rare syndromes,requires a multidisciplinary approach and an open mind to go beyond flow charts and diagnostic algorithms,in other words the ability to“think outside the box”.

关键词： cardiac masses cardiac tumors Cardio-oncology cardiac magnetic resonance Primitive cardiac tumors

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Diagnostic Dilemma of Intracardiac Mass: Tumor versus Thrombus-Case Series and Systematic Review

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Journal of Biosciences and Medicines 2024年第7期12卷 141-150页

作者： Indira Acharya Ashik Pokharel Raktim Ghosh Christopher J. Haas Department of Internal Medicine Internal Medicine Residency Program Medstar Health Baltimore MD USA Department of Cardiology MedStar Union Memorial Hospital MedStar Health Baltimore MD USA School of Medicine Georgetown University Washington D.C. USA

Background: The differential diagnosis for intracavitary cardiac masses is limited, typically including vegetations, tumors, or thrombi. cardiac thrombi can often mimic cardiac tumors on imaging, creating a diagnostic challenge. Primary cardiac tumors are rare and usually benign, whereas most cardiac tumors result from metastases, commonly originating from malignancies in the breast, lung, or melanoma. Aim: This report highlights the importance of distinguishing various cardiac masses based on clinical presentations, clinical courses, and radiological features. Case Presentation: We describe two cases of cardiac masses with unique and diverse clinical features. Each case posed significant diagnostic challenges due to their distinct presentations and clinical progressions. Conclusion: These cases underscore the importance of considering both benign and metastatic origins in the differential diagnosis of intracavitary cardiac masses. Accurate differentiation between thrombi and tumors is crucial for appropriate management and treatment.

关键词： Echocardiography cardiac masses Arrhythmias cardiac Magnetic Resonance Imaging cardiac Thrombi

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Bridging the gap in cardiac mass diagnosis:Advanced imaging,genetic associations,and biomarkers

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World Journal of Clinical Cases 2024年第22期12卷 4859-4864页

作者： Yi-Hao Loh Xu-Lin Hong School of Medicine School of MedicineZhejiang UniversityChinaHangzhou 310000Zhejiang ProvinceChina Department of Cardiology Sir Run Run Shaw HospitalCollege of MedicineZhejiang UniversityHangzhou 310000Zhejiang ProvinceChina

In this editorial we comment on the article by Huffaker et al published in a recent issue of the World Journal of Clinical *** focus on cardiac tumors linked to genetic syndromes and the differential diagnosis of cardiac *** cardiomyocytes lack the ability to actively divide,primary cardiac tumors are extremely rare across all ethnicities and age *** they occur,these tumors are often associated with genetic mutations and,occasionally,genetic *** underscores the importance of considering genetic mutations and syndromes when encountering these *** more common growths in the heart are thrombi and vegetations,which can mimic tumors,further making the differential diagnosis *** the imaging techniques,contrast-enhanced cardiac magnetic resonance imaging has the highest sensitivity for differential *** aid in the differential diagnosis of cardiac masses,especially thrombi,appropriate utilization of biomarkers(i.e.D-dimer level)may provide pivotal clinical *** a multidisciplinary approach that integrates personal history,epidemiological insights,imaging findings,genetic markers,and biomarkers is therefore critical in the diagnostic process of cardiac masses.

关键词： cardiac masses Genetic syndromes Thrombi Imaging D-dimer

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Case Report: Intracardiac Mass, the Importance of Early Diagnosis and Surgical Intervention

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Case Reports in Clinical Medicine 2021年第9期10卷 240-245页

作者： Samir Rafla Tarek Bishay Emeritus Professor of Cardiology Department Alexandria University Alexandria Egypt Cardiology Department National Heart Institute Cairo Egypt

Background: cardiac masses are not rare findings;they can be primary or secondary. The differential diagnosis may need surgical intervention in most cases. Case summary: A 42-year female presented with complaints of dyspnea, palpitations, ventricular premature beats, attacks of non-sustained ventricular tachycardia. Echocardiography revealed a myocardial septal mass on both sides in the right and left ventricles. The decision to operate was taken and the masses were removed. It was proved by histopathologic examination to be metastatic from her skin melanoma. Clinically, arrhythmias subsided. Conclusion: The decision of surgery proved unavoidable. Early diagnosis by surgical intervention is important for effective treatment.

关键词： Melanoma Case Report cardiac masses Echocardiography Surgical Intervention

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