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carbon nanoparticle Exerts Positive Growth Effects with Increase in Productivity by Down-Regulating Phytochrome B and Enhancing Internal Temperature in Rice

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Rice science 2021年第3期28卷 289-300,I0026,I0028页

作者： Madhusmita PANIGRAHY Subhashree DAS Yugandhar POLI Pratap Kumar SAHOO Khushbu KUMARI Kishore C.S.PANIGRAHI School of Biological Sciences National Institute of Science Education and Research(Homi Bhabha National Institute)Odisha 752050India Biofuel&Bioprocessing Research Center Institute of Technical Education and ResearchSiksha‘O’Anusandhan Deemed to be UniversityOdisha 751001India Indian Institute of Rice Research Rajendra NagarHyderabad 500030India School of Physical Science National Institute of Science Education and Research(Homi Bhabha National Institute)Odisha 752050India Center for Interdisciplinary Science National Institute of Science Education and Research(Homi Bhabha National Institute)Odisha 752050India Faculty of Biology and Biotechnology Ruhr University BochumBochum 44780Germany

The effects of carbon nanoparticle(CNP)on rice variety Swarna(MTU7029)were *** induced effects similar to shade avoidance response(SAR)of Arabidopsis,with increase in shoot length,root length,root number,cotyledon area,chlorophyll content and total sugar content in rice *** mature plants,CNP treatment resulted increase in plant height,number of productive tillers per plant,normalized difference vegetation index,quantum yield and root growth.A total of 320 mg of CNP per plant administered in four doses resulted in improved grain traits such as filled grain rate,100-grain weight,grain length/width ratio,hulling rate,milling rate and head rice *** from the CNP-treated plants showed increase in amylose,starch and soluble sugar contents compared to ***,CNP treatment showed an average of 17.5%increase in yield per *** investigation to the molecular mechanism behind CNP induction of SAR,a significant downregulation of phytochrome B transcript was *** in perception of red wavelengths led to responses similar to *** in plant’s internal temperature by 0.5ºC±0.1ºC was recorded after CNP *** suggest that the internalized CNP aggregates may serve to absorb extra photons thereby increasing the internal temperature of *** B accounts the hike in internal temperature and initiates a feed-back reduction of its own *** suggest that moderate SAR is beneficial for rice plants to improve agronomic traits and *** presents a potential non-transgenic method for improving rice yield by CNP treatment.

关键词： agronomic trait carbon nanoparticle flowering time rice grain quality phytochrome B yield shade avoidance response temperature sensing

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A green synthesis of carbon nanoparticles from honey and their use in real-time photoacoustic imaging

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Nano Research 2013年第5期6卷 312-325页

作者： Lina Wu Xin Cai Kate Nelson Wenxin Xing Jun Xia Ruiying Zhang Allen J. Stacy Micah Luderer Gregory M. Lanza Lihong V. Wang Baozhong Shen Dipanjan Pan C-TRAIN and Division of Cardiology Washington University School of Medicine 4320 Forest Park Avenue Saint Louis MO 63108 USA Key Laboratory of Molecular Imaging in College of Heilongjiang Province Department of Radiology the 4th Affiliated Hospital of Harbin Medical University Harbin 1S0001 China Optical Imaging Laboratory Department of Biomedical Engineering Washington University in St. Louis Campus Box 1097 One Brookings Drive St. Louis MO 63130 USA Nano Research Facility (NNIN-NSF) Washington University in St. Louis St. Louis MO 63130 USA

Imaging sentinel lymph nodes （SLN） could provide us with critical information about the progression of a cancerous disease. Real-time high-resolution intrao- perative photoacoustic imaging （PAI） in conjunction with a near-infrared （NIR） probe may offer opportunities for the immediate imaging for direct identification and resection of SLN or collecting tissue samples. In this work a commercially amenable synthetic methodology is revealed for fabricating luminescent carbon nanoparticles with rapid clearance properties. A one-pot ＂green＂ technique is pursued, which involved rapid surface passivation of carbon nanopartides with organic macromolecules （e.g., polysorbate, polyethyleneglycol） in solvent-free conditions. Interestingly, the naked carbon nanoparticles are derived for the first time, from commercial food grade honey. Surface coated particles are markedly smaller （-7 nm） than previously explored particles （gold, single-walled carbon nanotubes, copper） for SLN imaging. The results indicate an exceptionally rapid signal enhancement （-2 min） of the SLN. Owing to their strong optical absorption in the NIR region, tiny size and rapid lymphatic transport, this platform offers great potential for faster resection of SLN and may lower complications caused in axillary investigation by mismarking with dyes or low-resolution imaging techniques.

关键词： carbon nanoparticle honey,contrast agents photoacoustictomography real-time imaging

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Recent advances in photothermal and RNA interfering synergistic therapy

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Chinese Chemical Letters 2021年第3期32卷 1010-1016页

作者： Kun Li Mei Lu Xinhua Xia Yuanyu Huang School of Life Science Advanced Research Institute of Multidisciplinary ScienceInstitute of Engineering MedicineKey Laboratory of Molecular Medicine and BiotherapyBeijing Institute of TechnologyBeijing 100081China School of Pharmacy Hunan University of Chinese MedicineChangsha 410208China

As a new treatment technique,photothermal therapy(PTT)has aroused worldwide attention in cancer treatment,mainly due to its excellent absorption ability,easy regulation,and *** conversion materials with enhanced permeability and retention effect can be targeted easily to tumor *** can accumulate efficiently to tumor tissues and allow normal tissues and organs not to be affected by temperature,thus significantly helping to reduce the systemic toxicity and improve the antitumor ***,PTT alo ne often suffers from the rapeutic resistance and reduced therapeutic efficacy,due to photothermal nanomaterial-mediated fundamental cellular defense mechanism of heat shock response,which could be inhibited by small interfering RNA(siRNA).Nevertheless,photothermal conversion materials as an excellent siRNA delivery carrier may conside rably enhance the delivery efficiency of ***,photothermal and RNA interfering(RNAi)synergistic therapy has recently aroused extensive attention in tumor *** this review,we mainly summarize the recent advances of photothermal and RNAi synergistic therapy,including some synergistic therapeutic nanoplatforms of inorganic and organic photothermal materials and other combined therapies such as combining with small molecular antitumor agents or PDT/*** combination of various treatment techniques may considerably improve the synergistic therapeutic effect of PTT and RNAi in the treatment of cancers.

关键词： Photothermal therapy RNAi RNA interference siRNA Small interfering RNA Gold nanoparticle carbon nanoparticle

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Molecular dynamics study of the infiltration of lipid-wrapping C60 and polyhydroxylated single-walled nanotubes into lipid bilayers

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Frontiers of physics 2015年第2期10卷 57-66页

作者： Quan-Xing Guo Lei Zhang Yong Zhang School of Physics and Engineering Sun Yat-Sen University Guangzhou 510275 China

Because of the many potential medical applications of nanoparticles, considerable research has been conducted on the interactions between nanoparticles and biomembranes. We employed coarse- grained molecular dynamics simulations to study the infiltration of lipid-wrapping C60 and polyhy- droxylated single-walled nanotubes. Diffusion coefficients and scaling factors are adopted to quantify the diffusivity of the biomembranes, and the rupture tension is used to measure the lateral strength of the lipid bilayer. According to our simulations, all wrapped nanoparticles, except those wrapped by dipalmitoyl-glycero-phosphoglycerol, can be inserted into the bilayers. Our simulations also re- veal that the bilayers remain in free diffusion after the nanoparticle insertions while their diffusion coefficient can be altered significantly. The polyhydroxylated single-walled nanotubes lead to signif- icant changes to the lateral strength of biomembranes and this effect depends on the quantity of the inserted nanoparticles. The simulations demonstrate the feasibility of using these methods to deliver nanopartieles while some suggestions are given for choosing the appropriate lipids for wrappiug. The results also suggest that the functionalized nanopartieles could be applied in strengthening or weakening the lateral strength of biomembranes for specific purposes.

关键词： lipid bilayer carbon nanoparticle molecular dynamics

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