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calcium phosphate conversion technique:A versatile route to develop corrosion resistant hydroxyapatite coating over Mg/Mg alloys based implants

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Journal of Magnesium and Alloys 2022年第7期10卷 1821-1845页

作者： G.S.Hikku C.Arthi R.B.Jeen Robert K.Jeyasubramanian R.Murugesan Medical Bionanotechnology Faculty of Allied Health SciencesChettinad Hospital and Research InstituteChettinad Academy of Research and EducationKelambakkamTamilnadu 603103India Nanobiotechnology Amirta Centre for Nanoscience and Molecular MedicineAmirtha Vishwa VidhyapeethamErnakulamKerala 682041India Department of Mechanical Engineering AAA College of Engineering and TechnologySivakasiTamilnadu 626005India Department of Chemistry Mepco Schlenk Engineering CollegeSivakasiTamilnadu 626005India Karpaga Vinayaga Institute of Medical Sciences and Research Centre PalayanoorTamilnadu 603308India

Globally,vast research interest is emerging towards the development of biodegradable orthopedic implants as it overcomes the toxicity exerted by non-degradable implants when fixed in the human body for a longer *** this context,magnesium(Mg)plays a major role in the production of biodegradable implants owing to their characteristic degradation nature under the influence of body ***,Mg is one of the essential nutrients required to perform various metabolic activities by the human cells,and therefore,the degraded Mg products will be readily absorbed by the nearby ***,the higher corrosion rate in the biological environment is the primary downside of using Mg implants that liberate H2gas resulting in the formation of ***,in certain cases,Mg undergoes complete degradation before the healing of damaged bone tissue and cannot serve the purpose of providing mechanical ***,many studies have been focused on the development of different strategies to improve the corrosion-resistant behavior of Mg according to the *** this regard,the present review focused on the limitations of using pure Mg and Mg alloys for the fabrication of medical implants and how the calcium phosphate conversion coating alters the corrosive tendency through the formation of hydroxyapatite protective films for enhanced performance in medical implant applications.

关键词： Biodegradable implants Magnesium Controlled corrosion Alloying Hydroxyapatite calcium phosphate conversion coating

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