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RISK FActORS OF ct-guided percutaneous lung biopsy COMPLICATIONS

Medical Bulletin of Shanghai Jiaotong University 2012年第2期24卷 33-41页

作者：倪颖梦时国朝万欢英陈克敏吴达明 Department of Pulmonary Medicine Ruijin HospitalShanghai Jiaotong University School of Medicine Department of Radiology Ruijin HospitalShanghai Jiaotong University School of Medicine

Objective To evaluate the complication rate of ct-guided percutaneous lung biopsy and determine the risk factors for complications. MethodsA retrospective investigation of ct-guided percutaneous lung biopsy carried out between 2002 and 2009 was performed. The risk factors for complications were determined by multivariate analysis of variables related to patient demographics, lung lesions, and biopsy procedures. ResultsA total of 281 biopsy procedures were enrolled. The total complication rate was 55.9% with pneumothorax 32.4% (91/281) and bleeding 34.5% (97/281). The risk factors affecting pneumothorax rate were lesion location, lesion depth, and time of pleural pierce; and the risk factors affecting bleeding complications were lesion depth, lesion size, and age. predictive models for pneumothorax and bleeding were established by logistic regression. The pneumothorax model had a sensitivity of 80.0% with a specificity of 62.4%,and the bleeding model had a sensitivity of 67.4% with a specificity of 88.8%. ConclusionLesion location, lesion depth, and number of pleural passes were independent risk factors for pneumothorax. Lesion size, lesion depth, and age were independent risk factor for bleeding. The predictive models for pneumothorax and bleeding will helpfully reduce the complication of ct-guided lung biopsy.

关键词： ct-guided percutaneous lung biopsy pneumothorax bleeding predictive model

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