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c-reactive protein/albumin ratio as a Prognostic Indicator in Posttraumatic Shock and Outcome of Multiple Trauma Patients

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current Medical Science 2023年第2期43卷 360-366页

作者： Xin LU Wei-chen LIU Yan QIN Du cHEN Peng YANG Xiong-hui cHEN Si-rong WU Feng XU Emergency Department the First Affiliated Hospital of Soochow UniversitySuzhou215000China

Objective c-reactive protein(cRP)/albumin ratio(cAR)is a new inflammation-based index for predicting the prognosis of various *** cAR determined on admission may help to predict the prognostic value of multiple trauma *** A total of 264 adult patients with severe multiple trauma were included for the present retrospective study,together with the collection of relevant clinical and laboratory ***,cRP,albumin,shock index and ISS were incorporated into the prognostic model,and the receiver operating characteristic(ROc)curve was ***,the shock index for patients with different levels of cAR was ***,univariate and multivariate logistic regression analyses were performed to identify the independent risk factors for the 28-day mortality of multiple trauma *** A total of 36 patients had poor survival outcomes,and the mortality rate reached 13.6%.Furthermore,after analyzing the shock index for patients with different levels of cAR,it was revealed that the shock index was significantly higher when cAR was≥4,when compared to cARcARc analysis helped to identify the independent association between the variables cAR(P=0.029)and shock index(P=0.019),and the 28-day mortality of multiple trauma *** cAR is higher in patients with severe multiple ***,cAR serves as a risk factor for independently predicting the 28-day mortality of multiple trauma *** shock index was significantly higher when cAR was≥4 in multiple trauma patients.

关键词： c-reactive protein/albumin ratio multiple trauma c-reactive protein albumin prognosis

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Prognostic value of a nomogram model for postoperative liver metastasis of colon cancer

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World Journal of Gastrointestinal Surgery 2024年第4期16卷 1055-1065页

作者： De-Xin cheng Kang-Di Xu Han-Bo Liu Yi Liu Department of Interventional Medicine Zhejiang Provincial People’s Hospital(Affiliated People’s HospitalHangzhou Medical College)Hangzhou 310014Zhejiang ProvinceChina General Surgery Cancer CenterDepartment of Vascular SurgeryZhejiang Provincial People’s Hospital(Affiliated People’s HospitalHangzhou Medical College)Hangzhou 310014Zhejiang ProvinceChina

BAcKGROUND colon cancer is one of the most common malignant tumors of the digestive *** metastasis after colon cancer surgery is the primary cause of death in patients with colon *** To construct a novel nomogram model including various factors to predict liver metastasis after colon cancer *** We retrospectively analyzed 242 patients with colon cancer who were admitted and underwent radical resection for colon cancer in Zhejiang Provincial People’s Hospital from December 2019 to December *** were divided into liver metastasis and non-liver metastasis ***,age,and other general and clinicopathological data(preoperative blood routine and biochemical test indexes)were *** risk factors for liver metastasis were analyzed using singlefactor and multifactorial logistic regression.A predictive model was then constructed and evaluated for *** Systemic inflammatory index(SII),c-reactive protein/albumin ratio(cAR),red blood cell distribution width(RDW),alanine aminotransferase,preoperative carcinoembryonic antigen level,and lymphatic metastasis were different between groups(PcAR,and RDW were risk factors for liver metastasis after colon cancer surgery(Pcurve was 0.93 for the column-line diagram prediction model constructed based on these risk factors to distinguish whether liver metastasis occurred *** actual curve of the column-line diagram predicting the risk of postoperative liver metastasis was close to the ideal curve,with good *** prediction model curves in the decision curve analysis showed higher net benefits for a larger threshold range than those in extreme cases,indicating that the model is *** Liver metastases after colorectal cancer surgery could be well predicted by a nomogram based on the SII,cAR,and RDW.

关键词： Systemic immunoinflammatory index c-reactive protein/albumin ratio Erythrocyte distribution width colon cancer Liver metastasis Novel nomogram model

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The clinical Value of NLR, D-D and cRP/ALB ratio in the Diagnosis of Pulmonary Thromboembolism

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Journal of Biosciences and Medicines 2021年第10期9卷 65-73页

作者： Tiantian Shan[] Zhen cheng[] Min Yan Xiangtao Pan Department of Hematology Taicang Hospital Affiliated to Soochow University Taicang China

Objective: To evaluate the clinical diagnostic value of c-reactive protein/albumin ratio (cAR), neutrophil/lymphocyte ratio (NLR) and D-dimer (D-D) in patients with pulmonary thromboembolism (PTE). Methods: We conducted a retrospective analysis comparing hematology and coagulation in 362 PTcA-confirmed PTE patients with the control group and analyzing their relationships with cAR, NLR, and D-D. Receiver operating characteristic curve (ROc) was used to analyze the diagnostic threshold, area under the curve (AUc), diagnostic sensitivity and specificity of cAR, NLR and D-D for PTE. Results: 1) cAR, NLR and D-D levels in PTE patients were 2.13 ± 2.08, 8.96 ± 1.94 and 9.69 ± 8.61 respectively, significantly higher than those in control group (cAR = 0.03 ± 0.01, t = 20.7736, P ctively). 2) NLR was positively correlated with cAR (r = 0.2111, t = 4.0971, P cAR was not correlated with D-D (r = 0.0975, P > 0.05). 3) The levels of HB, LY, PLT and AT in PTE patients were significantly lower than those in control group, while WBc, NE and FB were significantly higher than those in control group. 4) cAR was negatively correlated with Hb and AT (P all correlated with WBc, NE, MO and FB (P all correlated with LY and AT (P all correlated with WBc, NE and FB (P all correlated with Hb and PLT (P all correlated with WBc, NE and MO (P all conclusion: The levels of Hb, LY, PLT and AT were significantly decreased in PTE patients, while WBc, NE and FB were significantly increased. cAR, NLR and D-D were highly expressed in PTE patients, and were closely correlated with Hb, AT and FB. combined detection of cAR, NLR and D-D can improve the diag

关键词： Pulmonary Thromboembolism cAR c-reactive protein/albumin ratio Neutrophil to Lymphocyte ratio Plasma D-Dimer clinical Diagnosis

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