检索结果-南通市图书馆

Functions and mechanisms of protein lysine butyrylation(Kbu):Therapeutic implications in human diseases

Genes & Diseases 2023年第6期10卷 2479-2490页

作者： Qianqian Xue Yanyan Yang Hong Li Xiaoxin Li Lu Zou Tianxiang Li Huibo Ma Hongzhao Qi Jianxun Wang Tao Yu Institute for Translational Medicine The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266000China Department of Immunology School of Basic MedicineQingdao UniversityQingdaoShandong 266021China Clinical Laboratory Central Laboratory.The Affiliated Qingdao Hiser Hospital of Qingdao UniversityQingdaoShandong 266000China Department of Vascular Surgery The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266000China Department of Cardiac Ultrasound The Affiliated Hospital of Qingdao UniversityQingdaoShandong 266000China

Post-translational modifications(PTM)are covalent modifications of proteins or peptides caused by proteolytic cleavage or the attachment of moieties to one or more amino *** play essential roles in biological function and regulation and have been linked with several *** of protein acylation(Kac),a type of PTM,are known to induce epigenetic regulatory processes that promote various ***,an increasing number of studies focusing on acylation modifications are being ***(Kbu)is a new acylation process found in animals and *** has been recently linked to the onset and progression of several diseases,such as cancer,cardiovascular diseases,diabetes,and vascular ***,the mode of action of certain drugs used in the treatment of lymphoma and colon cancer is based on the regulation of butyrylation levels,suggesting that butyrylation may play a therapeutic role in these *** addition,butyrylation is also commonly involved in rice gene expression and thus plays an important role in the growth,development,and metabolism of *** tools and analytical methods that could be utilized for the prediction and detection of lysine butyrylation have also been *** study reviews the potential role of histone Kbu,as well as the mechanisms underlying this *** also summarizes various enzymes and analytical methods associated with Kbu,with the goal of providing new insights into the role of Kbu in gene regulation and diseases.

关键词： butyrylation Gene regulation Histone Post-translational modification Target treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：